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Theramid DERMA-PEPTIDES for oily acne-prone skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Theramid DERMA-PEPTIDES

Low

  • AverageOily Skin Fit
  • AverageEffectiveness
  • HighSafety

A weak match for oily acne-prone skin; the moisturizers alongside fit it better.

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate moisturizing for your oily skin due to glycerin and propanediol, but lacks specialized ingredients to effectively target acne, blemishes, and breakouts.
  • Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 provide collagen stimulation and barrier repair, though stronger seboregulating ingredients would better address oiliness.
  • The formula is safe for your oily skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

How to apply

  • Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
  • Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
  • Gently press a small amount into your skin and avoid rubbing to keep pores clear.
  • Apply on clean, slightly damp skin to help the product absorb better and control oil.
  • Avoid the sensitive eye area and do a simple patch test before your first use.

People Say

★4.7Overall rating based on 300+ reviews

Users frequently praise this serum for its lightweight, non-sticky texture and its effectiveness in delivering visible anti-aging results, such as increased skin plumpness and reduced fine lines. It is also noted for its gentle, fragrance-free formulation, making it suitable for sensitive skin and compatible with other active ingredients.

Highlights

  • Visible anti-aging Mostly Mentioned
    • “Fine lines are less visible”
    • “Skin looks plumper”
    • “More youthful skin”
  • Gentle formulation Often Mentioned
    • “Suitable for sensitive skin”
    • “No strong scent”
    • “No sensitising occurring”
  • Lightweight texture Often Mentioned
    • “Absorbs quickly”
    • “Doesn't leave stickiness”
    • “Lotion-like texture”
  • Good value Sometimes Noted
    • “Price is unbeatable”
    • “Affordable serums”
    • “Quality for price”
  • Practical packaging Sometimes Noted
    • “Love the pump”
    • “Pipettes are annoying”
    • “Packaging pleases senses”
  • High expectations Rarely Noted
    • “Overhyped by influencers”
    • “Waiting for results”
    • “Not a miracle”
  • Limited availability Rarely Noted
    • “Hard to find in stores”
    • “Only online”
    • “Shipping delays”
  • Packaging preference Rarely Noted
    • “Prefer glass bottles”
    • “Pump can clog”
    • “Hard to see level”

Sources: lovi.care, nichebeautylab.com, skintskincare.com, reddit.com, youtube.com, and more

Questions and answers

Why is Theramid Derma-Peptides a weak match for oily acne-prone skin?

Theramid Derma-Peptides is a weak match for oily acne-prone skin because it lacks specialized ingredients to effectively target blemishes and breakouts, and it needs ingredients like Niacinamide, ceramides, or lightweight hyaluronic acid to manage oil and balance this skin type.

International Journal of Cosmetic Science, 2024Journal of Cosmetic Dermatology, 2015

Which ingredients make this cream a poor fit for oily acne-prone skin?

This cream is a weak match for oily acne-prone skin because it lacks targeted ingredients for breakouts and excess oil. A product of this type needs acne-fighting ingredients like Niacinamide, lightweight hydrators such as hyaluronic acid, and balancing components that do not clog pores.

What does Palmitoyl Tripeptide-1 do for oily acne-prone skin?

Palmitoyl tripeptide-1 helps firm the skin and smooth out fine lines, but it is not specifically designed to treat oily or acne-prone skin. To care for oily and acne-prone skin while targeting aging, this type of product needs lightweight hydrators and pore-clearing ingredients that keep the skin clear without feeling heavy.

Journal of Cosmetic Dermatology, 2026International Journal of Cosmetic Science, 2026

What does EGF do for oily acne-prone skin?

EGF helps calm redness and breakouts, and it may improve the look of acne scars on oily skin. It also supports the skin barrier while increasing skin water and oil balance.

Clinical, Cosmetic and Investigational Dermatology, 2023International Journal of Dermatology, 2014

Where does this cream go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after cleansing and before moisturizing, though an oily acne-prone skin of this type needs a product with specialized blemish-fighting and oil-controlling ingredients rather than just basic moisturizers and peptides.

Can I use it with retinol, and in what order?

You can use this treatment with retinol by applying the retinol first and following it with this moisturizing treatment. While this product is safe and unlikely to irritate your skin, it lacks specialized ingredients to target breakouts. Oily acne-prone skin needs balancing ingredients that control excess oil and clear blemishes.

Cutis, 2006

How often should I use this cream?

THERAMID DERMA-PEPTIDES can be applied daily as part of your evening routine to support skin barrier repair and collagen stimulation. However, because this moisturizing treatment is a weak match for oily acne-prone skin, it lacks specialized ingredients to target breakouts and needs ingredients that control oil.

Health Science Reports, 2021Journal of Cosmetic Dermatology, 2015

Can it clog pores, cause breakouts or purging for oily acne-prone skin?

This product is unlikely to clog pores or cause breakouts on oily skin, as it contains no harsh or irritating ingredients. However, because it lacks targeted ingredients for breakouts, this skin type needs a treatment featuring blemish-fighting ingredients and oil-balancing agents.

Can I use this cream around the eyes or on my body?

This cream is safe to use around the eyes and on your body, as it has a very gentle formula that is unlikely to cause irritation. However, because it is a weak match for oily acne-prone skin, this skin type needs specialized ingredients to effectively target acne, blemishes, and breakouts, along with stronger seboregulating ingredients to better address oiliness.

What the research says

  • Topical application of 1,3-propanediol at various concentrations, alone or combined with butylene glycol and/or glycerol, increased skin hydration and reduced trans epidermal water loss in 30 healthy female subjects over an 8-hour period, with the 15% concentration and the addition of glycerol providing greater benefits.

    International Journal of Cosmetic Science, 2024

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017

  • A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.

    Journal of Cosmetic Dermatology, 2015

  • Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.

    Journal of Cosmetic Dermatology, 2026

  • Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.

    International Journal of Cosmetic Science, 2026

  • Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone.

    The New England Journal of Medicine, 1989

  • Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba.

    Lasers in Surgery and Medicine, 2020

  • Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars.

    The Journal of Clinical and Aesthetic Dermatology, 2022

Why other moisturizers fit oily acne-prone skin better

Ingredients

Water, Glycerin, Propanediol, Caprylic Capric Triglyceride, Palmitoyl Tripeptide-1, Sh-Oligopeptide-1, Palmitoyl Tetrapeptide-7

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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How does it fit your skin?

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