Theramid DERMA-PEPTIDES for acne-prone skin
Palmitoyl Tripeptide-1
Sh-Oligopeptide-1
Palmitoyl Tetrapeptide-7
Average
- HighCombination Skin Fit
- AverageEffectiveness
- HighSafety
Works for acne-prone skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate moisturizing for your combination skin due to glycerin and propanediol, while Palmitoyl Tripeptide-1 and Sh-Oligopeptide-1 support collagen stimulation. This product provides general hydration but lacks specific ingredients to target your acne, blemishes, and breakouts.
- The formulation is highly suitable for combination skin and is safe with no risks of irritation, as it avoids harsh or prohibited ingredients.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
People Say
★4.7Overall rating based on 300+ reviewsUsers frequently praise this serum for its lightweight, non-sticky texture and its effectiveness in delivering visible anti-aging results, such as increased skin plumpness and reduced fine lines. It is also noted for its gentle, fragrance-free formulation, making it suitable for sensitive skin and compatible with other active ingredients.
Highlights
Visible anti-aging Mostly Mentioned
- “Fine lines are less visible”
- “Skin looks plumper”
- “More youthful skin”
Gentle formulation Often Mentioned
- “Suitable for sensitive skin”
- “No strong scent”
- “No sensitising occurring”
Lightweight texture Often Mentioned
- “Absorbs quickly”
- “Doesn't leave stickiness”
- “Lotion-like texture”
Good value Sometimes Noted
- “Price is unbeatable”
- “Affordable serums”
- “Quality for price”
Practical packaging Sometimes Noted
- “Love the pump”
- “Pipettes are annoying”
- “Packaging pleases senses”
High expectations Rarely Noted
- “Overhyped by influencers”
- “Waiting for results”
- “Not a miracle”
Limited availability Rarely Noted
- “Hard to find in stores”
- “Only online”
- “Shipping delays”
Packaging preference Rarely Noted
- “Prefer glass bottles”
- “Pump can clog”
- “Hard to see level”
Sources: lovi.care, nichebeautylab.com, skintskincare.com, reddit.com, youtube.com, and more
Questions and answers
How well does Theramid Derma-Peptides work for acne-prone skin?
THERAMID DERMA-PEPTIDES works moderately well for acne-prone skin, providing general hydration with glycerin and propanediol while peptides support firmness, though it lacks specific ingredients to target breakouts. A product of this type needs acne-fighting and hydrating ingredients like niacinamide, hyaluronic acid, or centella asiatica to care for acne-prone skin effectively.
Which ingredients make this treatment a good fit for acne-prone skin?
Glycerin and propanediol provide moderate moisture, while Palmitoyl Tripeptide-1 and Sh-Oligopeptide-1 support collagen, though this treatment lacks specific ingredients to target breakouts. A product of this type needs ingredients like Niacinamide, Hydrolyzed Hyaluronic Acid, and Centella Asiatica to address acne and hydrate acne-prone skin without causing excess oiliness.
What does Palmitoyl Tripeptide-1 do for acne-prone skin?
Palmitoyl tripeptide-1 may help support collagen and improve skin firmness, though it is not a direct treatment for acne. Acne-prone skin requires ingredients that calm redness, clear pores, and balance oil production.
Journal of Cosmetic Dermatology, 2026International Journal of Cosmetic Science, 2026
What does EGF do for acne-prone skin?
EGF helps calm acne-prone skin by reducing both inflamed and non-inflamed breakouts. It supports skin healing and barrier repair, making it a useful option for improving overall skin texture.
Where does this treatment go in a skincare routine for acne-prone skin?
This treatment goes in the evening routine after cleansing and before moisturizing, following Lovi's simple steps for extra safety around sun exposure. It is safe for acne-prone skin with no risks of irritation, though a product for this skin type also needs specific ingredients to target blemishes and breakouts.
Can I use this treatment with retinol, and in what order?
You can use this treatment with retinol by applying the treatment first and following it with your retinol, as the gentle formula helps keep skin comfortable without irritation. A product of this type for acne-prone skin needs ingredients that help clear blemishes and breakouts alongside soothing hydration.
How often should I use this treatment?
Use this treatment in your evening routine, applying it daily to keep your skin soft and hydrated while supporting collagen. This product is safe and unlikely to cause irritation, but because it lacks ingredients to target breakouts, acne-prone skin needs a product that includes clarifying acids or soothing ingredients to clear blemishes.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this treatment clog pores, cause breakouts or purging for acne-prone skin?
This treatment is unlikely to clog pores or cause breakouts because it avoids harsh ingredients and has a very safe profile, though it also lacks specific ingredients to target acne. A product for acne-prone skin needs ingredients that help clear blemishes and control breakouts alongside gentle hydration.
Can I use this treatment around the eyes or on my body?
You can safely use this moisturizing treatment around the eyes and on the body because its formulation is very gentle and avoids harsh ingredients. However, to effectively care for acne-prone skin, a product of this type needs targeted blemish-fighting ingredients alongside lightweight hydration.
What the research says
Topical application of 1,3-propanediol at various concentrations, alone or combined with butylene glycol and/or glycerol, increased skin hydration and reduced trans epidermal water loss in 30 healthy female subjects over an 8-hour period, with the 15% concentration and the addition of glycerol providing greater benefits.
International Journal of Cosmetic Science, 2024A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.
Journal of Cosmetic Dermatology, 2015Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.
Journal of Cosmetic Dermatology, 2026Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.
International Journal of Cosmetic Science, 2026Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone.
The New England Journal of Medicine, 1989Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba.
Lasers in Surgery and Medicine, 2020Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars.
The Journal of Clinical and Aesthetic Dermatology, 2022
Why other moisturizers fit acne-prone skin better
Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients.
The Australasian Journal of Dermatology, 1992Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.
Molecules, 2023
Ingredients
Water, Glycerin, Propanediol, Caprylic Capric Triglyceride, Palmitoyl Tripeptide-1, Sh-Oligopeptide-1, Palmitoyl Tetrapeptide-7
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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