Revision Skincare Revox™ Line Relaxer for mature skin
High
- HighNormal Skin Fit
- HighEffectiveness
- ExcellentSafety
One of the best serums for mature skin.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent wrinkle reduction for your normal skin, as Acetyl Hexapeptide-8 and Acetyl Octapeptide-3 promote line relaxation and Sodium Hyaluronate provides essential hydration.
- The inclusion of Arnica Montana Flower Extract and Tocopherol further supports skin health and resilience.
- The product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients.
How to apply
- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
People Say
★4.6Overall rating based on 200+ reviewsThe product is highly regarded for its ability to soften expression lines and enhance the effects of professional treatments. Most users experience smoother, refreshed skin. Some users with dry skin or specific makeup routines find the texture difficult to apply, and a small number report irritation or no visible improvement.
Highlights
Softens lines Mostly Mentioned
- “Visible softening of fine lines”
- “softened forehead lines”
- “improvement in crow's feet”
Extends Botox Often Mentioned
- “Boosts neurotoxin results”
- “works synergistically with neuromodulator”
- “great Botox alternative”
Expensive product Often Mentioned
- “This stuff is not cheap”
- “expensive for the results”
Lightweight, absorbs fast Sometimes Noted
- “Lightweight formula absorbs quickly”
- “sinks in quickly”
- “doesn't sit on skin”
Plumps and hydrates Sometimes Noted
- “Great at plumping up”
- “gives healthy glow”
- “skin looks refreshed”
Layering issues Sometimes Noted
- “Doesn't go on amazing under makeup”
- “concealer gets flaky”
- “hard to layer moisturizer”
Causes irritation Rarely Noted
- “First night I used it irritated my eyes”
- “forehead a little bit itchy”
No results Rarely Noted
- “Highlight the lines”
- “just ok”
- “didn't see improvement”
Sources: lovi.care, blairskincare.com, dermstore.com, rajanimd.com, revisionskincare.com, bluegraygal.com, and more
Questions and answers
What makes Revox Line Relaxer a great fit for mature skin?
This treatment is a great fit because it offers excellent wrinkle reduction for mature skin by using peptides like Acetyl Hexapeptide-8 and Acetyl Octapeptide-3 to help relax lines while Sodium Hyaluronate provides essential hydration. It is also very safe and unlikely to cause irritation since it lacks harsh ingredients, and it supports overall skin health with arnica flower extract and vitamin E.
American Journal of Clinical Dermatology, 2013Journal of Cosmetic Dermatology, 2017
Which ingredients make this serum a good fit for mature skin?
Acetyl Hexapeptide-8 and Acetyl Octapeptide-3 help smooth out lines, while Sodium Hyaluronate keeps dry areas hydrated. Additionally, Arnica Montana Flower Extract and Tocopherol support overall skin health without causing irritation.
American Journal of Clinical Dermatology, 2013Journal of Cosmetic Dermatology, 2017
What do Peptides do for mature skin?
Peptides help mature skin by triggering signals that encourage collagen production, which supports firmness and smooths the look of fine lines. They may improve skin elasticity and help repair signs of aging, though their effectiveness depends heavily on how well they penetrate the skin surface.
International Journal of Cosmetic Science, 2009Biomolecules, 2025
What does Hyaluronic Acid do for mature skin?
Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Journal of Drugs in Dermatology, 2011Skin Research and Technology, 2024
Where does this serum go in a skincare routine for mature skin?
This treatment goes in the evening routine after cleansing and before moisturizing, which keeps it simple and safe around sun exposure. It is unlikely to cause irritation because it lacks harsh ingredients, and it helps smooth lines and keep skin hydrated.
Can I use this serum with retinol, and in what order?
You can use this treatment alongside retinol by applying the serum first and letting it absorb before putting on your retinol. This pairing is unlikely to irritate your skin, as the formula is gentle and focuses on smoothing lines and providing hydration.
American Journal of Clinical Dermatology, 2013Journal of Cosmetic Dermatology, 2017
How often should I use this serum?
This treatment is applied in the evening as part of your routine for mature skin. It helps smooth lines and hydrate your normal skin safely without irritation, and it is unlikely to cause any adverse effects.
American Journal of Clinical Dermatology, 2013Journal of Cosmetic Dermatology, 2017
Can this serum clog pores, cause breakouts or purging for mature skin?
This treatment is unlikely to clog pores or cause breakouts for mature skin, as it has a very low risk of irritation and lacks harsh ingredients.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group.
American Journal of Clinical Dermatology, 2013Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear.
Journal of Cosmetic Dermatology, 2017Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects.
Journal of Cosmetic and Laser Therapy, 2013A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.
Journal of Cosmetic Dermatology, 2020Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine.
Journal of Pharmacy & Pharmaceutical Sciences, 2015Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Gels containing 1% Arnica montana L. flower extract successfully enhanced the volume of the lips and face with a reduction of wrinkles in humans.
International Journal of Cosmetic Science, 2023Topical application of Arnica montana ointment reduced the inflammatory response and oxidative damage in mice exposed to UVB radiation compared to untreated UVB-exposed skin.
Cutaneous and Ocular Toxicology, 2020The protocol combining microcurrent with topical Arnica montana reduces inflammation, increases myofibroblast proliferation, and decreases macrophage presence in rats with skin lesions compared to controls.
International Journal of Experimental Pathology, 2023Gamma-aminobutyric acid treatment accelerated the cutaneous wound healing process by suppressing inflammation and stimulating reepithelialization in rats compared with epidermal growth factor treatment.
Journal of Microbiology and Biotechnology, 2007Topical application of gamma-aminobutyric acid and GABA(A) receptor-specific agonists accelerated cutaneous barrier recovery and prevented epidermal hyperplasia induced by barrier disruption in hairless mice compared to untreated controls.
The Journal of Investigative Dermatology, 2002Water-soluble hydrolysate and active constituents GABA and GABA-Alanine from Rhodosorus marinus significantly inhibited the release of IL-1α and NGF and decreased TRPV1 over-expression under PMA-induced inflammatory conditions in in vitro models of normal human keratinocytes and astrocytes.
Marine Drugs, 2018
Ingredients
Water, Glycerin, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Palmitoyl Tripeptide-28, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Aminobutyric Acid, Palmitoyl Tetrapeptide-7, Acetyl Hexapeptide-1, Palmitoyl Hexapeptide-19, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Sodium Hyaluronate, Inulin, Arnica Montana Flower Extract, Celery Extract Callus Extract, Anigozanthos Flavidus Extract, Steareth-20, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Pentylene Glycol, Caprylyl Glycol, Disodium Edta, Ethylhexylglycerin, Potassium Sorbate, Aminomethyl Propanol, Phenoxyethanol, Chlorhexidine Digluconate, Tocopherol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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