Goldfaden MD Radical Difference for oily skin
Sodium Hyaluronate
Aspalathus Linearis Extract
Lactobacillus Acerola Cherry Ferment
Saccharomyces Zinc Ferment
Saccharomyces Magnesium Ferment
Average
- HighOily Skin Fit
- AverageEffectiveness
- HighSafety
Works for oily skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate hydration for your oily skin due to sodium hyaluronate, which provides plumping effects, while Saccharomyces Zinc Ferment and Saccharomyces Magnesium Ferment support seboregulation and barrier repair.
- While beneficial for general skincare, the formula does not directly target the reduction of oily shine as a primary concern.
- The product is safe for your oily skin, with no risks of irritation from harsh or prohibited ingredients.
How to apply
- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
Questions and answers
How well does Radical Difference work for oily skin?
Goldfaden MD Radical Difference works decently for your oily skin by offering moderate hydration and supporting your skin barrier, though it does not directly target the reduction of oily shine. A treatment for this skin needs ingredients like niacinamide, ferulic acid, or zinc PCA to control sebum production and manage excess oil while keeping the skin comfortable.
Dermatologic Therapy, 2022Journal of Pharmacy & Pharmaceutical Sciences, 2015
Which ingredients make this serum a good fit for oily skin?
Sodium hyaluronate provides moderate hydration, while Saccharomyces zinc ferment and Saccharomyces magnesium ferment help support seboregulation and barrier repair for your oily skin. To be a better fit for oily skin, a treatment of this type needs ingredients like niacinamide, ferulic acid, and zinc PCA to control sebum production and manage oily shine.
Dermatologic Therapy, 2022Journal of Pharmacy & Pharmaceutical Sciences, 2015
What does Hyaluronic Acid do for oily skin?
Hyaluronic acid helps oily skin by reducing extra oil and sebum production without causing irritation. Clinical studies show it successfully balances oil levels while keeping the skin comfortable.
What does Roobos Extract do for oily skin?
Rooibos extract helps calm redness and balances excess oil so your skin feels fresh and clean. Its soothing properties help keep pores clear and are unlikely to cause irritation.
Where does this serum go in a skincare routine for oily skin?
This treatment goes in the evening routine, after cleansing and before moisturizing, for simplicity and extra safety around sun exposure. While this product is safe and offers moderate hydration, oily skin needs ingredients that directly target and reduce oily shine.
Can I use this serum with retinol, and in what order?
You can use this treatment with retinol by applying the treatment first and following with your retinol. It is unlikely to cause irritation on oily skin, but an ideal product for this skin type should also actively help reduce oily shine.
How often should I use this serum?
You can use this treatment in the evening as part of your routine. Oily skin also needs ingredients that directly control excess shine and balance oil production.
Can this serum clog pores, cause breakouts or purging for oily skin?
This treatment is unlikely to clog pores or cause breakouts on oily skin, as it is safe and free of harsh ingredients. However, because it does not directly target oily shine, oily skin often needs a product with ingredients that actively control excess oil.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.
Dermatologic Therapy, 2022Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine.
Journal of Pharmacy & Pharmaceutical Sciences, 2015Optimized transfersomes loaded with epigallocatechin-3-gallate and hyaluronic acid increased cell viability while reducing lipid peroxidation, intracellular ROS, and MMP expression in HaCaT cells, and exhibited higher skin permeation and deposition compared to plain EGCG.
Drug Delivery, 2017Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Ginkgo formulation increased skin moisturization by 27.88% and smoothness by 4.32% while reducing roughness by 0.4% and wrinkles by 4.63%, and significantly improved skin moisturization compared to the tea and rooibos formula.
International Journal of Cosmetic Science, 2010The addition of Aspalathus linearis extracts to topical sunscreen formulas containing OMC and BMDBM increased protection factors by up to 50% and protected the filters against photodegradation under radiation doses up to 14.4 standard erythemal doses.
Photochemical & Photobiological Sciences, 2026The combination of fermented and unfermented Aspalathus linearis extracts showed a synergistic photoprotective effect on Normal Human Dermal Fibroblast survival after UVB radiation, which further improved when combined with Polypodium leucotomos extract.
International Journal of Molecular Sciences, 2025Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline.
Experimental Dermatology, 2008
Why other serums fit oily skin better
A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.
Journal of Cosmetic Dermatology, 2024Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo.
BioMed Research International, 2022
Ingredients
Water, Sodium Hyaluronate, Aspalathus Linearis Extract, Lactobacillus Acerola Cherry Ferment, Saccharomyces Zinc Ferment, Saccharomyces Magnesium Ferment, Saccharomyces Iron Ferment, Saccharomyces Silicon Ferment, Phenoxyethanol, Ethylhexylglycerin
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Dr. Sofía Perea Pérez, MD, MSc
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Specialist dermatologist, MBBS, MD, IFAAD
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Elina Nazarenko, MD
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Victoria Derkova, MS
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