Eucerin UreaRepair Plus 10% Urea Lotion for skin with dark spots

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical 40% urea cream achieved improvement in less time and showed superiority over 12% ammonium lactate lotion in skin roughness, fissure reduction, thickness, and dryness at day 14 in patients treated for moderate to severe xerosis.

  American Journal of Clinical Dermatology, 2002

• Topical treatment with K101 achieved a significantly higher mycological cure rate compared to placebo in patients with ≤50% nail involvement (27.2% vs 10.4%), while showing early visible improvements in nail appearance and no safety issues.

  Mycoses, 2012

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

  Journal of Drugs in Dermatology, 2012

• Specially neutralized 12% lactate lotion provided significantly greater reductions in xerosis severity scores compared with a nonlactated emollient lotion and a 5% lactic acid lotion during the post-treatment regression period in sixty patients with moderate to severe xerosis.

  Archives of Dermatology, 1983

• Long-pulsed alexandrite laser achieved a significantly greater mean percent reduction in pigmentation area compared to topical tretinoin-ammonium lactate (25.7% versus 18.3%) in 15 patients with bilateral axillary acanthosis nigricans over 14 weeks.

  Caspian Journal of Internal Medicine, 2016

• Topical application of 5% aqueous lactate lotion twice a day for 1 year achieved a 90-100% reduction in inflammatory lesions in 40.9% of patients and in non-inflammatory lesions in 22.7% of patients, with most patients showing significant reduction in lesion counts.

  Indian Journal of Dermatology, Venereology and Leprology, 2002

Why other products fit skin with dark spots better

• Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.

  The British Journal of Dermatology, 2002

• Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2014

• Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers.

  International Journal of Medical Sciences, 2021

Ingredients

Water, Urea, Glycerin, Isopropyl Stearate, Dicaprylyl Ether, Glyceryl Glucoside, Sodium Lactate, Butyrospermum Parkii Butter, Tapioca, Polyglyceryl-4 Diisostearate-Polyhydroxystearate-Sebacate, Carnitine, Cetearyl Alcohol, Ceramide Np, Arginine Hcl, Sodium Pca, Histidine, Alanine, Citrulline, Lysine, Serine, Lactic Acid, Sodium Chloride, Mannitol, Sucrose, Glutamic Acid, Threonine, Glycogen, 1-2-Hexanediol, Phenoxyethanol, Potassium Sorbate, Arginine, Pca

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.