Glycolic acid and palmitoyl tripeptide-1
Keep them apart
Use them at different times of day, applying glycolic acid in the morning and the peptide in the evening, because the acid cancels out the peptide. The strong acid breaks down the peptide and stops it from firming your skin. You can use the acid in the morning and the peptide at night to get the benefits of both.
Glycolic acid products
- The Ordinary Glycolic Acid 7% Toning Solution
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RoC
Retinol Correxion Deep Wrinkle Night Cream
S$35.46
- First Aid Beauty KP Bump Eraser Body Scrub
- First Aid Beauty Facial Radiance Pads
- Murad Rapid Dark Spot Correcting Serum
- Skinbetter Science AlphaRet Overnight Cream
- St. Ives Apricot Scrub
-
COSRX
AHA/BHA Clarifying Treatment Toner
S$16.86
-
Dr. Dennis Gross
Alpha Beta Universal Daily Peel
S$141.06
- Pixi Glow Tonic
-
Good Molecules
Overnight Exfoliating Treatment
S$43.99
-
CeraVe
Skin Renewing Nightly Exfoliating Treatment
S$35.46
Palmitoyl tripeptide-1 products
- The Ordinary Multi-Peptide + Copper Peptides 1% Serum
- The Ordinary Multi-Peptide + HA Serum
- Medik8 Liquid Peptides
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Shiseido
Benefiance Wrinkle Smoothing Eye Cream
S$55.43
- Clinique Smart Clinical Repair Wrinkle Correcting Serum
- Alastin Skincare Regenerating Skin Nectar
- The Ordinary Matrixyl 10% + HA
- ZO Skin Health Daily Power Defense
- The INKEY List Collagen Peptide Serum
- Alastin Ultra Nourishing Moisturizer
-
DRMTLGY
Needle-less Serum
S$94.18
- Valmont Prime Renewing Pack
Questions and answers
Can you use glycolic acid and palmitoyl tripeptide-1 together?
Keep glycolic acid and palmitoyl tripeptide-1 apart in your routine because the low pH of the acid may destabilize the peptide bonds and reduce their bioactivity. Use them in separate steps or routines, such as AM and PM, to protect your skin.
Which goes first, glycolic acid or palmitoyl tripeptide-1?
Keep glycolic acid and palmitoyl tripeptide-1 apart in your routine because the low pH of glycolic acid destabilizes the peptide bonds and reduces bioactivity.
Are glycolic acid and palmitoyl tripeptide-1 good for sensitive skin?
No, you should keep glycolic acid and palmitoyl tripeptide-1 apart because the low pH of the acid can destabilize the peptide bonds and reduce its effectiveness. For sensitive skin, it is best to use them in separate steps or routines, such as using one in the morning and the other at night.
Research on glycolic acid and palmitoyl tripeptide-1
Behind this pairing advice
Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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