Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation
Niacinamide · Antioxidants, 2021Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress
Camellia sinensis extract, Camellia sinensis · Carcinogenesis, 2001Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence
Curcuma longa, Curcuma longa root powder · Phytotherapy Research, 2016Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
Alcohol · International Journal of Toxicology, 2001Formation and stability of oil-in-water nanoemulsions containing rice bran oil: in vitro and in vivo assessments
Rice bran oil, Japanese rice · Journal of Nanobiotechnology, 2011Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence
Sodium hyaluronate, Hyaluronic acid, 8-types hyaluronic acid · Dermatologic Therapy, 2022Topical use of dexpanthenol in skin disorders
Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review
Aloe barbadensis leaf juice · Iranian Journal of Medical Sciences, 2019Collagen Hydrolysates for Skin Protection: Oral Administration and Topical Formulation
Water collagen · Antioxidants, 2020Bifidobacterium longum lysate, a new ingredient for reactive skin
1 · Experimental Dermatology, 2010Cutaneous photoprotection from ultraviolet injury by green tea polyphenols
Camellia sinensis extract · Journal of the American Academy of Dermatology, 2001Improvement of naturally aged skin with vitamin A (retinol)
Retinol · Archives of Dermatology, 2007Regulatory effects of Lactobacillus plantarum-GMNL6 on human skin health by improving skin microbiome
Lactobacillus, Probiotics · International Journal of Medical Sciences, 2021The skin protective effects of compound K, a metabolite of ginsenoside Rb1 from Panax ginseng
Red ginseng extract · Journal of Ginseng Research, 2018Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo
Ascorbic acid sodium ascorbyl phosphate · Experimental Dermatology, 2003Nicotinic acid/niacinamide and the skin
Niacin · Journal of Cosmetic Dermatology, 2004Lactobacillus reuteri DSM 17938-A comparative study on the effect of probiotics and lysates on human skin
Probiotics · Experimental Dermatology, 2019Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial
Tocopherol, Tocopherol vitamin e plant, Ascorbic acid, Vitamins e, Violet c ascorbic acid · Journal of Cosmetic Dermatology, 2020A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation
Ferulic acid · Journal of the American Academy of Dermatology, 2008Geraniol attenuates 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced oxidative stress and inflammation in mouse skin: possible role of p38 MAP Kinase and NF-κB
Rosa damascena oil flower · Experimental and Molecular Pathology, 2013Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin
Ferulic acid · Journal of Cosmetic Dermatology, 2008The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study
Melaleuca alternifolia tree oil leaf, Tree · Indian Journal of Dermatology, Venereology and Leprology, 2007Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics
Collagen, Water-soluble collagen · Dermatology Practical & Conceptual, 2022Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Retinol · International Journal of Cosmetic Science, 2017Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
Palmitoyl pentapeptide-4 · International Journal of Cosmetic Science, 2005Psychophysical study of the effects of topical application of menthol in healthy volunteers
Menthol · Pain, 2006Acne Treatment Based on Selective Photothermolysis of Sebaceous Follicles with Topically Delivered Light-Absorbing Gold Microparticles
24k gold · The Journal of Investigative Dermatology, 2015Combination of microneedling and glycolic acid peels for the treatment of acne scars in dark skin
Saccharum officinarum extract · Journal of Cosmetic Dermatology, 2011Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent
Opuntia ficus-indica stem extract, Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015Protecting skin photoaging by NF-kappaB inhibitor
Magnolia officinalis bark extract · Current Drug Metabolism, 2010Aging skin is functionally anaerobic: importance of coenzyme Q10 for anti aging skin care
Ubiquinone · BioFactors, 2008Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica
Opuntia ficus-indica stem extract, Hydrolyzed opuntia ficus-indica flower extract, Cactus extract · BioMed Research International, 2015The Effect of Lactobacillus plantarum Extracellular Vesicles from Korean Women in Their 20s on Skin Aging
Probiotics, Lactobacillus · Current Issues in Molecular Biology, 2022Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Ascorbic acid sodium ascorbyl phosphate, Ascorbyl glucoside · Journal of Periodontology, 2009Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing
Retinol · The British Journal of Dermatology, 2019Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin
Scutellaria baicalensis root extract · Journal of Drugs in Dermatology, 2014Antioxidant, Wound Healing Potential and In Silico Assessment of Naringin, Eicosane and Octacosane
Grapefruit seed oil · Molecules, 2023Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skin
Panax ginseng root extract, Panax ginseng extract · Journal of Ginseng Research, 2017Bog blueberry anthocyanins alleviate photoaging in ultraviolet-B irradiation-induced human dermal fibroblasts
Blueberry fruit extract · Molecular Nutrition & Food Research, 2009Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study
Pronalen fruit acids · Journal of the American Academy of Dermatology, 1996Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women
Glutathione · Clinical, Cosmetic and Investigational Dermatology, 2014Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Chamomilla recutita flower extract matricaria flower extract, Chamomilla recutita flower extract, Chamomile extract, Chamomilla recutita extract matricaria extract · International Journal of Molecular Medicine, 2016Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract
Madecassoside, Centella asiatica extract, Centella asiatica meristem cell culture, Centella asiatica leaf water, Asiaticoside, Madecassic acid · Indian Journal of Pharmaceutical Sciences, 2016Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling
Panax ginseng root extract, Panax ginseng extract · Journal of Ethnopharmacology, 2007Ginsenosides repair UVB-induced skin barrier damage in BALB/c hairless mice and HaCaT keratinocytes
Hydrolyzed ginseng saponins · Journal of Ginseng Research, 2022Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter
Titanium dioxide · International Journal of Cosmetic Science, 2000The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction
Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy
Centella asiatica extract · Pharmaceutics, 2024Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
Phyto squalane extract, Squalane · Scientific Reports, 2020Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects
Ubiquinone · BioFactors, 2015Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations
Melaleuca alternifolia tree oil leaf, Aloe barbadensis leaf juice, Aloe barbadensis, Aloe barbadensis polysaccharides leaf, Propolis extract, Aloe barbadensis juice, Aloe barbadensis leaf water, Aloe barbadensis leaf extract, Aloe barbadensis powder, Tree, Aloe barbadensis leaf juice powder · Clinical Pharmacology, 2018Use of Collagen in Cosmetic Products
Collagen, Water-soluble collagen · Current Issues in Molecular Biology, 2024Antioxidant properties evaluation of topical astaxanthin formulations as anti-aging products
Algae extract · Journal of Cosmetic Dermatology, 2019Urea: a comprehensive review of the clinical literature
Urea · Dermatology Online Journal, 2013Anti-aging efficacy of topical formulations containing niosomes entrapped with rice bran bioactive compounds
Japanese rice, Rice essence · Pharmaceutical Biology, 2012The use of sulfur in dermatology
Sulfur · Journal of Drugs in Dermatology, 2004Effect of Camellia japonica oil on human type I procollagen production and skin barrier function
Camellia japonica seed oil, Camellia japonica leaf extract, Camellia japonica flower extract · Journal of Ethnopharmacology, 2007Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin
Ceramides, Ceramide · Scientific Reports, 2022Topical benzoyl peroxide for acne
Benzoyl peroxide · The Cochrane Database of Systematic Reviews, 2020Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes
Opuntia ficus-indica stem extract, Cactus extract · Journal of Medicinal Food, 2015The polysaccharide and low molecular weight components of Opuntia ficus indica cladodes: Structure and skin repairing properties
Opuntia ficus-indica stem extract, Hydrolyzed opuntia ficus-indica flower extract · Carbohydrate Polymers, 2017Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin
Glyceryl glucoside · Skin Pharmacology and Physiology, 2012Hyperoside and Quercitrin in Houttuynia cordata Extract Attenuate UVB-Induced Human Keratinocyte Cell Damage and Oxidative Stress via Modulation of MAPKs and Akt Signaling Pathway
Houttuynia cordata extract · Antioxidants, 2022Calendula extract: effects on mechanical parameters of human skin
Calendula officinalis oil · Acta Poloniae Pharmaceutica, 2011Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study
Ascorbic acid · Clinical Oral Investigations, 2021Depositing α-mangostin nanoparticles to sebaceous gland area for acne treatment
Garcinia mangostana peel extract · Journal of Pharmacological Sciences, 2015Sacha Inchi Oil (Plukenetia volubilis L.), effect on adherence of Staphylococus aureus to human skin explant and keratinocytes in vitro
Plukenetia volubilis seed oil · Journal of Ethnopharmacology, 2015Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin
Ceramide np, Ceramide eop · International Journal of Dermatology, 2008Effects of Locally Applied Glycerol and Xylitol on the Hydration, Barrier Function and Morphological Parameters of the Skin
Xylitol, Aquaxyl, Xylitylglucoside · Acta Dermato-venereologica, 2017Niosomal Nanocarriers for Enhanced Dermal Delivery of Epigallocatechin Gallate for Protection against Oxidative Stress of the Skin
Green tea water · Pharmaceutics, 2022Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation
Tocopherol, Tocopherol vitamin e, Ascorbic acid, Vitamins e · Journal of Cosmetic Dermatology, 2020Antioxidant Artemisia princeps Extract Enhances the Expression of Filaggrin and Loricrin via the AHR/OVOL1 Pathway
Artemisia princeps leaf powder, Artemisia princeps extract · International Journal of Molecular Sciences, 2017Licochalcone A activates Nrf2 in vitro and contributes to licorice extract-induced lowered cutaneous oxidative stress in vivo
Licorice root extract, Glycyrrhiza glabra root extract licorice root extract · Experimental Dermatology, 2015Injectable thermo-sensitive and wide-crack self-healing hydrogel loaded with antibacterial anti-inflammatory dipotassium glycyrrhizate for full-thickness skin wound repair
Dipotassium glycyrrhizate · Acta Biomaterialia, 2022Efficacy of probiotic-derived lotion from Lactobacillus paracasei MSMC 39-1 in mild to moderate acne vulgaris, randomized controlled trial
Lactobacillus · Journal of Cosmetic Dermatology, 2022Epilobium angustifolium extract demonstrates multiple effects on dermal fibroblasts in vitro and skin photo-protection in vivo
Epilobium angustifolium stem extract flower leaf · General Physiology and Biophysics, 2013Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study
Retinyl palmitate · International Journal of Nanomedicine, 2021Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris
Azelaic acid · Pharmaceutics, 2021Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin
Centella asiatica leaf extract, Cicaliao · Experimental Dermatology, 2008Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls
Camellia sinensis leaf extract · Experimental Dermatology, 2009A review of topical high-concentration L-menthol as a translational model of cold allodynia and hyperalgesia
Menthol · European Journal of Pain, 2014Mechanistic Wound Healing and Antioxidant Potential of Moringa oleifera Seeds Extract Supported by Metabolic Profiling, In Silico Network Design, Molecular Docking, and In Vivo Studies
Moringa oleifera seed extract · Antioxidants, 2022Comparison of clinical and histological effects between lactobacillus-fermented Chamaecyparis obtusa and tea tree oil for the treatment of acne: an eight-week double-blind randomized controlled split-face study
Melaleuca alternifolia tree oil leaf · Dermatology, 2014A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin
Myristyl nicotinate · Experimental Dermatology, 2007Rose Petal Extract (Rosa gallica) Exerts Skin Whitening and Anti-Skin Wrinkle Effects
Rosa gallica flower extract · Journal of Medicinal Food, 2020The clinical effect of glutathione on skin color and other related skin conditions: A systematic review
Glutathione · Journal of Cosmetic Dermatology, 2019The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study
Glycerin, Madecassoside, Madecassic acid · Clinical, Cosmetic and Investigational Dermatology, 2017The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial
Madecassoside, Centella asiatica meristem cell culture, Centella asiatica leaf water, Asiaticoside · Journal of Alternative and Complementary Medicine, 2020Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy
Niacinamide · Journal of Cosmetic Dermatology, 2021Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure
Benzoyl peroxide · Journal of Shoulder and Elbow Surgery, 2021Effects of cosmetics containing purified honeybee (Apis mellifera L.) venom on acne vulgaris
Bee venom · Journal of Integrative Medicine, 2013The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide
Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug
Benzoyl peroxide · American Journal of Clinical Dermatology, 2022Bioactive Glycyrrhizic Acid Ionic Liquid Self-Assembled Nanomicelles for Enhanced Transdermal Delivery of Anti-Photoaging Signal Peptides
Peptides, Palmitoyl pentapeptide-4 · Advanced Science, 2025Cytotoxicity of lecithin-based nanoemulsions on human skin cells and ex vivo skin permeation: Comparison to conventional surfactant types
Hydrogenated lecithin · International Journal of Pharmaceutics, 2019Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging
Montmorillonite, Bentonite, Bentonite clay, Clay, Pink clay, Volcanic clay · Carbohydrate Polymers, 2017Human skin penetration and local effects of topical nano zinc oxide after occlusion and barrier impairment
Calamine · European Journal of Pharmaceutics and Biopharmaceutics, 2016The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study
Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013Treatment of human skin with an extract of Fucus vesiculosus changes its thickness and mechanical properties
Algae extract · Journal of Cosmetic Science, 2002Protective effects of Camellia japonica flower extract against urban air pollutants
Camellia japonica flower extract · BMC Complementary and Alternative Medicine, 2019Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy
Oleanolic acid · Nanoscale Research Letters, 2020Effect of São Pedro do Sul thermal water on skin irritation
Water hungarian thermal water · International Journal of Cosmetic Science, 2010A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora
Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study
Saccharum officinarum extract, Glycolic acid · Journal of Cosmetic Dermatology, 2019Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging
Niacinamide · Scientific Reports, 2024A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population
Salicylic acid, Bha salicylic acid · BioMed Research International, 2020Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation
Tocopheryl acetate · Urologia Internationalis, 2019Magnolia ovovata extract and its active component magnolol prevent skin photoaging via inhibition of nuclear factor kappaB
Magnolia officinalis bark extract · European Journal of Pharmacology, 2007Formulation and evaluation on human skin of a water-in-oil emulsion containing Muscat hamburg black grape seed extract
Grape seed oil · International Journal of Cosmetic Science, 2015A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial
Melaleuca alternifolia tree oil leaf, Tree · Archives of Dermatological Research, 2022Exploring the Synergistic Effect of Bergamot Essential Oil with Spironolactone Loaded Nano-Phytosomes for Treatment of Acne Vulgaris: In Vitro Optimization, In Silico Studies, and Clinical Evaluation
Bergamot · Pharmaceuticals, 2023Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration
Adenosine · International Journal of Cosmetic Science, 2018Effects of lecithin-based nanoemulsions on skin: Short-time cytotoxicity MTT and BrdU studies, skin penetration of surfactants and additives and the delivery of curcumin
Lecithin, Hydrogenated lecithin · International Journal of Pharmaceutics, 2020Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris
Mandelic acid · Journal of Cosmetic Dermatology, 2020Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide
Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012Topical beta-carotene protects against infra-red-light-induced free radicals
Beta-carotene · Experimental Dermatology, 2011Structural characterization and in vivo evaluation of retinyl palmitate in non-ionic lamellar liquid crystalline system
Retinyl palmitate · Colloids and Surfaces. B, Biointerfaces, 2011Fermented pomegranate extracts protect against oxidative stress and aging of skin
Punica granatum extract · Journal of Cosmetic Dermatology, 2022Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial
Allantoin, Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020Evaluation of anti-acne properties of phloretin in vitro and in vivo
Phloretin · International Journal of Cosmetic Science, 2016A pilot randomized double-blind placebo-controlled trial on topical chamomile (Matricaria chamomilla L.) oil for severe carpal tunnel syndrome
Chamomilla recutita flower extract matricaria flower extract, Chamomilla recutita extract matricaria extract · Complementary Therapies in Clinical Practice, 2015High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin
Witch hazel extract, Witch hazel leaf extract, Witch hazel leaf water, Witch hazel bark extract · Phytochemistry, 2001Efficacy of Oxybrasion in the Treatment of Acne Vulgaris: A Preliminary Report
Sea salt · Journal of Clinical Medicine, 2022Self-Assembled Cubic Liquid Crystalline Nanoparticles for Transdermal Delivery of Paeonol
Paeonia suffruticosa root extract · Medical Science Monitor, 2015The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study
Glycolic acid, Gluconolactone, Aha blend glycolic and citric acids · Clinical, Cosmetic and Investigational Dermatology, 2019Anti-melanogenic property of ginsenoside Rf from Panax ginseng via inhibition of CREB/MITF pathway in melanocytes and ex vivo human skin
Panax ginseng extract · Journal of Ginseng Research, 2021Topical glutathione amino acid precursors protect skin against environmental and oxidative stress
Glutathione · Journal of the European Academy of Dermatology and Venereology, 2024Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study
Ascorbyl tetraisopalmitate, Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days
Ascorbyl tetraisopalmitate · Journal of Cosmetic Dermatology, 2019Snail Slime Extracted by a Cruelty Free Method Preserves Viability and Controls Inflammation Occurrence: A Focus on Fibroblasts
Snail secretion filtrate · Molecules, 2023Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy
Madecassoside, Centella asiatica extract, Centella asiatica leaf extract, Centella asiatica meristem cell culture, Centella asiatica leaf water · Molecules, 2023Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin
Acetyl hexapeptide-8, Argireline hexapeptide · Annals of Dermatology, 2019In vivo anti-ageing activity of cream containing niosomes loaded with purple glutinous rice (Oryza sativa Linn.) extract
Rice extract, Japanese rice · International Journal of Cosmetic Science, 2020A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Gluconolactone, Pha · The Australasian Journal of Dermatology, 1992Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula
Saccharomyces rice ferment filtrate, Pitera essence, Saccharomyces ferment filtrate, Galactomyces ferment filtrate, Saccharomyces rice bran ferment, Rice ferment filtrate sake ferment filtrate · Journal of Clinical Medicine, 2021Korean Red Ginseng extract ameliorates melanogenesis in humans and induces antiphotoaging effects in ultraviolet B-irradiated hairless mice
Red ginseng extract · Journal of Ginseng Research, 2020Allergy to oxidized limonene and linalool is frequent in the U.K
Citrus aurantium dulcis peel oil, Limonene · The British Journal of Dermatology, 2014Hesperidin Suppresses Melanosome Transport by Blocking the Interaction of Rab27A-Melanophilin
Glucosyl hesperidin · Biomolecules & Therapeutics, 2013Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach
Zinc oxide, Zinc, Calamine · Journal of Controlled Release, 2025Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study
Salicylic acid, Bha salicylic acid · Journal of Cosmetic Dermatology, 2024Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects
Vitamin e · Journal of Cosmetic Dermatology, 2020High-Payload Nanosuspension of Centella asiatica Extract for Improved Skin Delivery with No Irritation
Asiaticoside · International Journal of Nanomedicine, 2021Rosmarinic Acid, as an NHE1 Activator, Decreases Skin Surface pH and Improves the Skin Barrier Function
Rosmarinus officinalis leaf extract · International Journal of Molecular Sciences, 2022Inhibition of TRPV1 prevented skin irritancy induced by phenoxyethanol. A preliminary in vitro and in vivo study
Phenoxyethanol · International Journal of Cosmetic Science, 2017An oil-soluble extract of Rubus idaeus cells enhances hydration and water homeostasis in skin cells
Rubus idaeus fruit extract raspberry fruit extract · International Journal of Cosmetic Science, 2015Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment
Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study
Clay, Jojoba seed oil, Argilla · Forschende Komplementarmedizin, 2012A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid
Ceramide np · Skin Pharmacology and Physiology, 2022A Novel Biocompatible Herbal Extract-Loaded Hydrogel for Acne Treatment and Repair
Extracts · Oxidative Medicine and Cellular Longevity, 2021Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil
Avocado oil, Crocus sativus · Journal of Cosmetic Dermatology, 2020Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications
Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2015Effect of Cirsium japonicum Flower Extract on Skin Aging Induced by Glycation
Floral extracts · Molecules, 2022Hormesis-based anti-aging products: a case study of a novel cosmetic
Hydrolyzed ginseng saponins · Dose-response, 2013Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris
Azelaic acid · Dermatology and Therapy, 2024A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide
Salicylic acid, Bha salicylic acid · Journal of Drugs in Dermatology, 2023Chemical peels for acne vulgaris: a systematic review of randomised controlled trials
Mandelic acid · BMJ Open, 2018Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs
Vitamin e · Journal of Cosmetic Dermatology, 2022Comparison of skin calming effects of cosmetic products containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on capsaicin-induced facial stinging in volunteers with sensitive skin
Acetyl dipeptide-1 cetyl ester · Journal of the European Academy of Dermatology and Venereology, 2016Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial
Centella asiatica leaf extract, Cicaliao · Journal of Cosmetic Dermatology, 2019NAD-Driven Sirtuin Activation by Cordyceps sinensis Extract: Exploring the Adaptogenic Potential to Promote Skin Longevity
Cordyceps sinensis extract · International Journal of Molecular Sciences, 2024Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies
Benzoyl peroxide · Journal of the American Academy of Dermatology, 2023A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial
Ginkgo biloba leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2015Effects of a lotion containing probiotic ferment lysate as the main functional ingredient on enhancing skin barrier: a randomized, self-control study
1 · Scientific Reports, 2023The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols
2-hexanediol · International Journal of Cosmetic Science, 2011Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques
Ascorbyl tetraisopalmitate · European Journal of Pharmaceutics and Biopharmaceutics, 2017Nanogel Containing Gamma-Oryzanol-Loaded Nanostructured Lipid Carriers and TiO2/MBBT: A Synergistic Nanotechnological Approach of Potent Natural Antioxidants and Nanosized UV Filters for Skin Protection
Rice extract · Pharmaceuticals, 2023Microwave-assisted and chemically tailored chlorogenic acid-functionalized silver nanoparticles of Citrus sinensis in gel matrix aiding QbD design for the treatment of acne
Lonicera japonica flower extract honeysuckle flower extract, Colloidal silver · Journal of Cosmetic Dermatology, 2023Oxidized citrus oil (R-limonene): a frequent skin sensitizer in Europe
Citrus aurantium dulcis peel oil · Journal of the American Academy of Dermatology, 2002Topical application of superoxide dismutase mediated by HIV-TAT peptide attenuates UVB-induced damages in human skin
Superoxide dismutase · European Journal of Pharmaceutics and Biopharmaceutics, 2016Safety and efficacy of Sclerocarya birrea (A.Rich.) Hochst (Marula) oil: A clinical perspective
Sclerocarya birrea seed oil · Journal of Ethnopharmacology, 2015Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations
Vitamin e · Journal of Cosmetic Dermatology, 2022Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial
Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022Efficacy of cosmetic formulations containing dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin
Magnesium ascorbyl phosphate · Photochemistry and Photobiology, 2012Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study
Zinc gluconate · Clinical, Cosmetic and Investigational Dermatology, 2023Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model
Jojoba seed oil · Frontiers in Pharmacology, 2024Challenging the safety and efficacy of topically applied chlorogenic acid, apigenin, kaempferol, and naringenin by HET-CAM, HPLC-TBARS-EVSC, and laser Doppler flowmetry
Grapefruit peel extract · Frontiers in Chemistry, 2024Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function
Propanediol · International Journal of Cosmetic Science, 2024A Rose Extract Protects the Skin against Stress Mediators: A Potential Role of Olfactory Receptors
Rose extract, Black rose extract, Rosa centifolia flower extract · Molecules, 2020Camellioside A, isolated from Camellia japonica flowers, attenuates UVA-induced production of MMP-1 in HaCaT keratinocytes via suppression of MAPK activation
Camellia japonica flower extract · Experimental and Therapeutic Medicine, 2021Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial
Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020Effect of inhaler and topical lavender oil on pain management of arteriovenous fistula cannulation
Lavender oil · The Journal of Vascular Access, 2023Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release
Oenothera biennis flower extract · Biomaterials Advances, 2022A new dermocosmetic containing retinaldehyde, delta-tocopherol glucoside and glycylglycine oleamide for managing naturally aged skin: results from in vitro to clinical studies
Tocopheryl glucoside · Clinical, Cosmetic and Investigational Dermatology, 2017The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study
Acetyl hexapeptide-8, Argireline hexapeptide · Journal of Cosmetic Dermatology, 2017The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study
Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris
Capryloyl salicylic acid, Citric acid · Journal of Cosmetic Dermatology, 2021Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract
Camellia sinensis leaf extract, Matcha green tea, Black tea extract, Aloe barbadensis flower extract, Camellia sinensis leaf water, Garcinia mangostana peel extract · Clinical, Cosmetic and Investigational Dermatology, 2019Amino acid complex (AAComplex) benefits in cosmetic products: In vitro and in vivo clinical studies
Aacomplex · Journal of Cosmetic Dermatology, 2022Whitening effect of alpha-bisabolol in Asian women subjects
Bisabolol · International Journal of Cosmetic Science, 2010Reversing UVB-induced photoaging with Hibiscus sabdariffa calyx aqueous extract
Hibiscus sabdariffa flower extract · Journal of the Science of Food and Agriculture, 2020Evaluation of moisturizing and irritation potential of sacha inchi oil
Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison
Willow bark extract, Salix nigra bark extract willow bark extract · Journal of Cosmetic Dermatology, 2019Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract
Willow bark extract, Salix nigra bark extract willow bark extract · Planta Medica, 2019Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers
Sodium ascorbyl phosphate · Drug Research, 2017An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging
Salix nigra bark extract willow bark extract, Willow bark extract · Journal of Cosmetic Dermatology, 2010Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study
Beta-glucan · Journal of Cosmetic Dermatology, 2021Comparative benefit of two thermal spring waters after photodynamic therapy procedure
Avene thermal spring water avene aqua · Journal of Cosmetic Dermatology, 2007Assessment of Cosmetic and Dermatological Properties and Safety of Use of Model Skin Tonics with Kombucha-Fermented Red Berry Extracts
Saccharomyces xylinum black tea ferment · International Journal of Molecular Sciences, 2022Whitening effect of Sophora flavescens extract
Sophora angustifolia root extract · Pharmaceutical Biology, 2013Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin
Capryloyl salicylic acid · Journal of Cosmetic Dermatology, 2008Partially purified paeoniflorin exerts protective effects on UV-induced DNA damage and reduces facial wrinkles in human skin
Paeonia albiflora root extract · Journal of Cosmetic Science, 2006Topical microemulsion containing Punica granatum extract: its control over skin erythema and melanin in healthy Asian subjects
Punica granatum extract, Punica granatum extract fruit ferment · Postepy Dermatologii I Alergologii, 2014Understanding Solar Skin Elastosis-Cause and Treatment
Witch hazel leaf water · Journal of Cosmetic Science, 2018Pilot Study of Topical Copper Chlorophyllin Complex in Subjects With Facial Acne and Large Pores
Chlorophyll · Journal of Drugs in Dermatology, 2015A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris
Terminalia ferdinandiana fruit extract · Dermatologic Therapy, 2020In vivo spectrophotometric evaluation of skin barrier recovery after topical application of soybean phytosterols
Phytosterols · Journal of Cosmetic Science, 2008'All-natural' anti-wrinkle emulsion serum with Acmella oleracea extract: A design of experiments (DoE) formulation approach, rheology and in vivo skin performance/efficacy evaluation
Acmella oleracea extract · International Journal of Cosmetic Science, 2021Spirulina, Palmaria Palmata, Cichorium Intybus, and Medicago Sativa extracts in cosmetic formulations: an integrated approach of in vitro toxicity and in vivo acceptability studies
Red seaweed · Cutaneous and Ocular Toxicology, 2019Use of the synthetic superoxide dismutase/catalase mimetic EUK-134 to compensate for seasonal antioxidant deficiency by reducing pre-existing lipid peroxides at the human skin surface
Superoxide dismutase · International Journal of Cosmetic Science, 2004Antiaging, Brightening, and Antioxidant Efficacy of Fermented Bilberry Extract (Vaccinium myrtillus): A Randomized, Double-Blind, Placebo-Controlled Trial
Vaccinium myrtillus fruit extract · Nutrients, 2024Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration
Betaine, Aloe barbadensis flower extract · Molecules, 2024Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial
Ferulic acid · The Journal of Dermatological Treatment, 2025Comprehensive assessment of the efficacy and safety of a clay mask in oily and acne skin
Clay, Argilla · Skin Research and Technology, 2023Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast
Squalane, Phyto squalane extract · Molecules, 2025Effects of lactobionic acid peel, aluminum oxide crystal microdermabrasion, and both procedures on skin hydration, elasticity, and transepidermal water loss
Lactobionic acid · Journal of Cosmetic Dermatology, 2019Effect of facial application of essence containing royal jelly extract on stratum corneum moisture content: A placebo-controlled, double-blind, parallel-group study
Royal jelly extract, Royal jelly · Journal of Cosmetic Dermatology, 2022Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement
Adenosine · Journal of Cosmetic Dermatology, 2019Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders
3-o-ethyl ascorbic acid · Polymers, 2023Grifolin derivatives from Albatrellus ovinus as TRPV1 receptor blockers for cosmetic applications
Albatrellus ovinus extract · International Journal of Cosmetic Science, 2017Repair of acetone- and sodium lauryl sulphate-damaged human skin barrier function using topically applied emulsions containing barrier lipids
Phytosphingosine · Journal of the European Academy of Dermatology and Venereology, 2002Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment
Asiatic acid, Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024Preparation, characterization, and application of polysaccharide-based emulsions incorporated with lavender essential oil for skin-friendly cellulosic support
Lavender essential oil · International Journal of Biological Macromolecules, 2021Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol
Sorbitol · Journal of Cosmetic Science, 2013A clinical evaluation of the efficacy and tolerability of a novel topical antioxidant formulation featuring vitamin C, astaxanthin, and fermented turmeric
Red algae extract · Journal of Cosmetic Dermatology, 2023Chemical Profile and Promising Applications of Cucurbita pepo L. Flowers
Pumpkin fruit extract · Antioxidants, 2024Morinda citrifolia Linn. (Rubiaceae) leaf extracts mitigate UVB-induced erythema
Morinda citrifolia extract · Journal of Natural Medicines, 2009Betula alba Bark Extract and Empetrum nigrum Fruit Juice, a Natural Alternative to Niacinamide for Skin Barrier Benefits
Betula alba juice · International Journal of Molecular Sciences, 2022Enzyme-Treated Caviar Prevents UVB Irradiation-Induced Skin Photoaging
Caviar extract · Marine Drugs, 2022Stability, antioxidant activity, in vivo safety and efficacy of creams with standardized wild apple fruit extract: a comparison of conventional and biodegradable emulsifiers
Pyrus malus fruit extract · International Journal of Cosmetic Science, 2019Development of grape seed extract based formulations by using non-invasive biophysical technique and its impact on skin aging
Grape seed oil · Pakistan Journal of Pharmaceutical Sciences, 2021Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis
Borago officinalis oil, Borago officinalis seed oil · Lipids, 2020Research on antioxidant performance of diglucosyl gallic acid and its application in emulsion cosmetics
Diglucosyl gallic acid · International Journal of Cosmetic Science, 2022Design and in vivo evaluation of emulgel formulations including green tea extract and rose oil
Rosa damascena oil flower, Rosa damascena oil flower rose oil flower · Acta Pharmaceutica, 2013Effects of Hydroxydecine(®) (10-hydroxy-2-decenoic acid) on skin barrier structure and function in vitro and clinical efficacy in the treatment of UV-induced xerosis
Royal jelly extract, Royal jelly · European Journal of Dermatology, 2011A study of anti-wrinkle functions and improvement of cream with Phaseolus angularis
Phaseolus angularis seed powder · International Journal of Cosmetic Science, 2024Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis
Yeast extract · Journal of Clinical Medicine, 2023Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres
Papain, Carica papaya extract, Carica papaya fruit extract, Carica papaya · Giornale Italiano Di Dermatologia E Venereologia, 2015Randomized prospective study of low-dose isotretinoin alone and combination with salicylic acid and mandelic peel against acne tarda
Mandelic acid · Journal of Cosmetic Dermatology, 2022Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin
Copper tripeptide-1 · Archives of Facial Plastic Surgery, 2006Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025Lipid ingredients in moisturizers can modulate skin responses to UV in barrier-disrupted human skin in vivo
Phytosphingosine · Journal of Dermatological Science, 2012Treatment of Postinflammatory Hyperpigmentation Following Acne With Microneedling and Panax Ginseng-Derived Exosomes
Panax ginseng extract, Panax ginseng root extract · Plastic and Reconstructive Surgery. Global Open, 2025Gene expression profile of human follicle dermal papilla cells in response to Camellia japonica phytoplacenta extract
Camellia japonica flower extract · FEBS Open Bio, 2021Safety evaluation of traces of nickel and chrome in cosmetics: The case of Dead Sea mud
Sea silt · Regulatory Toxicology and Pharmacology, 2015Unique natural exopolysaccharides for biomimetic protective effect against urban pollution
Algae exopolysaccharides · Journal of Cosmetic Science, 2017Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception
N.m.f · Skin Research and Technology, 2022Investigating the Anti-Aging Effects of Caviar Oil on Human Skin
Caviar extract · In Vivo, 2023Comparative Analysis of Water Extracts from Roselle (Hibiscus sabdariffa L.) Plants and Callus Cells: Constituents, Effects on Human Skin Cells, and Transcriptome Profiles
Hibiscus sabdariffa flower extract · International Journal of Molecular Sciences, 2023Permeation, metabolism and site of action concentration of nicotinic acid derivatives in human skin. Correlation with topical pharmacological effect
Hexyl nicotinate · European Journal of Pharmaceutical Sciences, 2003Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid
Betaine · Pharmaceutics, 2024Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence
Zinc oxide, Calamine · Biomedicines, 2025The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively
Betaine · Skin Research and Technology, 2003A novel water-in-oil emulsion with a lecithin-modified bentonite prevents skin damage from urban dust and cedar pollen
Clay, Lecithin · International Journal of Cosmetic Science, 2020Starch- and carboxymethyl cellulose-based films as active beauty masks with papain incorporation
Carica papaya fruit extract · International Journal of Biological Macromolecules, 2023Skin recovery by Lavandula angustifolia leaf callus extract: Redox control of Nrf2 signaling
Lavandula angustifolia oil lavender oil · Free Radical Biology & Medicine, 2025Algae extract protection effect on oxidized protein level in human stratum corneum
Algae extract · Annals of the New York Academy of Sciences, 2004Nanowire-based squalene oleogel repairs skin photoaging
Squalane · Journal of Nanobiotechnology, 2025Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid
Lactobionic acid, Phas polyhydroxy acids · Journal of Cosmetic Dermatology, 2010Investigation of antiaging and skin rejuvenation potential of phyto-constituents from Pyrus communis loaded topical emulgel
Pyrus communis fruit extract · Pakistan Journal of Pharmaceutical Sciences, 2019Lipid nanocarriers containing Passiflora edulis seeds oil intended for skin application
Passiflora edulis seed oil · Colloids and Surfaces. B, Biointerfaces, 2020Comparison of topical purslane & topical 0.1% triamcinolone acetonide in the management of oral lichen planus - a double blinded clinical trial
Portulaca oleracea extract · BMC Oral Health, 2023Effect of myristyl nicotinate on retinoic acid therapy for facial photodamage
Myristyl nicotinate · Experimental Dermatology, 2007Influence of vitamin E acetate on stratum corneum hydration
Tocopheryl acetate, Tocopheryl acetate vitamin e · Arzneimittel-Forschung, 1998Rosa gallica and its active compound, cyanidin-3,5-O-diglucoside, improve skin hydration via the GLK signaling pathway
Rosa gallica flower extract · BioFactors, 2023Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles
Phenylethyl resorcinol · Journal of Cosmetic Dermatology, 2021Clinical study of Asian skin changes after application of a sunscreen formulation containing grape seed extract
Palmitoyl grape seed extract · Journal of Cosmetic Dermatology, 2022HYVIA™: A novel, topical chia seed extract that improves skin hydration
Salvia hispanica seed extract · Journal of Cosmetic Dermatology, 2020Topical lycopene emulgel significantly improves biophysical parameters of human skin
Tomato extract · European Journal of Pharmaceutics and Biopharmaceutics, 2022A randomized controlled study to evaluate the depigmenting activity of L-ascorbic acid plus phytic acid-serum vs. placebo on solar lentigines
Phytic acid · Journal of Cosmetic Dermatology, 2011Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment
Moringa oleifera seed extract · Polymers, 2022Development of a cream formulation containing bee venom and other bee products
Royal jelly · Journal of Cosmetic Dermatology, 2022A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo
Shea butter · Journal of Cosmetic Dermatology, 2022Anti-inflammatory and skin-hydrating properties of a dietary supplement and topical formulations containing oligomeric proanthocyanidins
Grape seed oil · Skin Pharmacology and Physiology, 2007Modulation of lipid fluidity likely contributes to the fructose/xylitol-induced acceleration of epidermal permeability barrier recovery
Xylitylglucoside · Archives of Dermatological Research, 2019Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study
Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects
Sodium ascorbyl phosphate · Experimental Dermatology, 2012Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects
Cucumis sativus extract, Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024Salicin and Hederacoside C-Based Extracts and UV-Absorbers Co-Loaded into Bioactive Lipid Nanocarriers with Promoted Skin Antiaging and Hydrating Efficacy
Salix nigra bark extract willow bark extract · Nanomaterials, 2022A 10% Lactobionic acid-containing moisturizer reduces skin surface pH without irritation-An in vivo/in vitro study
Lactobionic acid · Journal of Cosmetic Dermatology, 2019Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study
Hydrolyzed hyaluronic acid, Hydrolyzed sodium hyaluronate · Aesthetic Plastic Surgery, 2026Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin
Vitamin e · Journal of Cosmetic Dermatology, 2024Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer
Saccharomyces rice ferment filtrate, Pitera essence, Saccharomyces ferment filtrate, Galactomyces ferment filtrate, Saccharomyces rice bran ferment, Rice ferment filtrate sake ferment filtrate · Journal of Clinical Medicine, 2022Three clinical studies showing the anti-aging benefits of sodium salicylate in human skin
Sodium salicylate · Journal of Cosmetic Dermatology, 2010Efficacy and Safety of a New Cosmeceutical Regimen Based on the Combination of Snail Secretion Filtrate and Snail Egg Extract to Improve Signs of Skin Aging
Snail secretion filtrate · The Journal of Clinical and Aesthetic Dermatology, 2020Cranberry Oil: A Potent Natural Intimate Care Ingredient Displaying Antioxidant and Anti-Inflammatory Effects and Promoting Beneficial Vaginal Lactobacillus
Cranberry · International Journal of Molecular Sciences, 2025Anti-Photoaging Effects of Upcycled Citrus junos Seed Anionic Peptides on Ultraviolet-Radiation-Induced Skin Aging in a Reconstructed Skin Model
Citrus junos · International Journal of Molecular Sciences, 2024Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes
3-o-ethyl ascorbic acid, Ethyl ascorbic acid · Free Radical Biology & Medicine, 2025Formulation and evaluation of exotic fat based cosmeceuticals for skin repair
Mangifera indica seed butter · Indian Journal of Pharmaceutical Sciences, 2008Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
2-hexanediol, Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum
Diglycerin · Journal of Oleo Science, 2016Magnolia biondii flower extract attenuates UVB-induced skin damage through high-mobility group box protein B1
Floral extracts · International Journal of Cosmetic Science, 2024Development of topical drug delivery system with Sphaeranthus indicus flower extract and its investigation on skin as a cosmeceutical product
Floral extracts · Journal of Cosmetic Dermatology, 2020Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays
Propanediol, Xylitol · Molecules, 2021Evaluation of the anti-aging effects of Zinc-α2-glycoprotein peptide in clinical and in vitro study
Glycoproteins · Skin Research and Technology, 2024Standardized wild apple fruit extract as a bioactive agent in dermocosmetic products for efficacy skin hydration-In vitro and in vivo evaluation
Pyrus malus fruit extract · Journal of Cosmetic Dermatology, 2022The effect of a vitamin A palmitate and antioxidant-containing oil-based moisturizer on photodamaged skin of several body sites
Retinyl palmitate · Journal of Cosmetic Dermatology, 2013A dermocosmetic product containing the sap of oat plantlets and Garcinia mangostana extract improves the clinical signs of acne
Garcinia mangostana peel extract · Journal of the European Academy of Dermatology and Venereology, 2024Combining Topical and Oral Botanicals for Skin Redness, Pigmentation, Sleep, and Mood: A Randomized Controlled Study
Crocus sativus · Journal of Clinical Medicine, 2022New targets in the battle against dandruff
Epilobium angustifolium stem extract flower leaf · Journal of Cosmetic Science, 2017Hexyl-nicotinate-induced vasodilation in normal human skin
Hexyl nicotinate · Dermatologica, 1987Functional properties and skin care effects of sodium trehalose sulfate
Trehalose · Skin Research and Technology, 2024Hippophae rhamnoides oil-in-water (O/W) emulsion improves barrier function in healthy human subjects
Hippophae rhamnoides extract, Hippophae rhamnoides oil · Pakistan Journal of Pharmaceutical Sciences, 2014Protective effects of Paeonia suffruticosa callus extract in skin through anti-inflammation and repair UVB-induced damage
Paeonia suffruticosa root extract · International Journal of Cosmetic Science, 2025Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence
Adenosine · International Journal of Molecular Sciences, 2026Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Hydrolyzed hyaluronic acid, Hydrolyzed sodium hyaluronate, Low molecular weight hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients
3-o-ethyl ascorbic acid, Ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026Liposomal formulation of a vitamin C derivative: a promising strategy to increase skin permeability
3-o-ethyl ascorbic acid · Journal of Liposome Research, 2025Development and efficacy assessments of tea seed oil makeup remover
Camellia oleifera seed oil · Annales Pharmaceutiques Francaises, 2017A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females
Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris
Capryloyl salicylic acid · Journal of Drugs in Dermatology, 2013Glycerol crosslinked vitamin E loaded xanthan gum and gellan gum nanoemulgels for topical management of dry skin
Xanthan gum · International Journal of Biological Macromolecules, 2025Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum
Caprylic capric triglyceride · Life, 2023Clinical efficacy of facial masks containing yoghurt and Opuntia humifusa Raf. (F-YOP)
Yogurt · Journal of Cosmetic Science, 2011Green Synthesis of Copper Oxide Nanoparticles using Cucumis Sativus (Cucumber) Extracts and their Bio-Physical and Biochemical Characterization for Cosmetic and Dermatologic Applications
Cucumis sativus juice · Endocrine, Metabolic & Immune Disorders Drug Targets, 2021Effect of isosecotanapartholide isolated from Artemisia princeps Pampanini on IL‑33 production and STAT‑1 activation in HaCaT keratinocytes
Artemisia princeps leaf powder, Artemisia princeps leaf extract · Molecular Medicine Reports, 2017Genotoxicity of micro- and nano-particles of kaolin in human primary dermal keratinocytes and fibroblasts
Purifying clay, Kaolin · Genes and Environment, 2020Poly-γ-Glutamic Acid from a Novel Bacillus subtilis Strain: Strengthening the Skin Barrier and Improving Moisture Retention in Keratinocytes and a Reconstructed Skin Model
Polyglutamic acid · International Journal of Molecular Sciences, 2025Evaluation of additive effects of hydrolyzed jojoba (Simmondsia chinensis) esters and glycerol: a preliminary study
Jojoba esters · Journal of Cosmetic Dermatology, 2008Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy
Tocopheryl acetate, Tocopheryl acetate vitamin e, Vitamin e tocopheryl acetate · Scientific Reports, 2025Photoprotective, Antioxidant and Anti-Inflammatory Effects of Aged Punica granatum Extract: In Vitro and In Vivo Insights
Punica granatum extract, Punica granatum extract fruit ferment · Food Science & Nutrition, 2025In vitro, ex vivo and clinical approaches to evaluate the potential effect of Gentiana lutea extract on skin
Gentiana lutea root extract · International Journal of Cosmetic Science, 2023Improving the outcome of treating striae gravidarum by combined therapies using topical β-glucan and 1565-nm non-ablative fractional laser: A prospective randomized vehicle-controlled parallel group study
Beta-glucan · The Journal of Dermatology, 2022Clinical study of a spray containing birch juice for repairing sensitive skin
Betula alba juice · Archives of Dermatological Research, 2023Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging
Ascorbyl tetraisopalmitate, Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024Treatment of Stretch Marks Using a New Formulation Combining Nanofractional Radiofrequency Plus Magnetic Nanofractional Radiofrequency
Beta-glucan · Dermatology and Therapy, 2023Preliminary safety and in vivo efficacy of Acmella oleracea extract-loaded glycolipid emulsion serum-Effects on ocular irritation, dermal absorption, and facial skin biophysical and microrelief properties
Acmella oleracea extract · International Journal of Cosmetic Science, 2025Beneficial modulation from a high-purity caviar-derived homogenate on chronological skin aging
Caviar extract · Rejuvenation Research, 2012Antioxidant activities and skin hydration effects of rice bran bioactive compounds entrapped in niosomes
Rice essence · Journal of Nanoscience and Nanotechnology, 2011Protective properties of Avène Thermal Spring Water on biomechanical, ultrastructural and clinical parameters of human skin
Water hungarian thermal water · Journal of the European Academy of Dermatology and Venereology, 2020κ-Carrageenan tetrasaccharide ameliorates particulate matter-induced defects in skin hydration of human keratinocytes cells and skin barrier disorders
Chondrus crispus extract · International Journal of Biological Macromolecules, 2025Development of nanofiber facial mask inspired by the multi-function of dried ginger (Zingiberis Rhizoma) essential oil
Zingiber officinale oil root · Scientific Reports, 2025Sodium hydroxide-induced subclinical irritation. A test for evaluating stratum corneum barrier function
Sodium hydroxide · Acta Dermato-venereologica, 1990Sustained effect of two antioxidants (oxothiazolidine and δ-tocopheryl glucoside) for immediate and long-term sun protection in a sunscreen emulsion based on their different penetrating properties
Tocopheryl glucoside · International Journal of Cosmetic Science, 2021Safety assessment and toxicological profiling of a novel combinational sunprotective dermal formulation containing melatonin and pumpkin seed oil
Pumpkin seed oil · Regulatory Toxicology and Pharmacology, 2017Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling
Portulaca oleracea extract, Lactobacillus portulaca oleracea extract ferment · Cutaneous and Ocular Toxicology, 2022Impact of Hydrocolloid Dressing and Moisturizing Cream as Facial Skin Protectants Among Health Care Workers
Dimethicone · Military Medicine, 2024Investigating the Effects of a Manuka Honey, Royal Jelly, and Bee Venom-Derived Face Serum on Skin Health and Signs of Aging
Royal jelly extract, Royal jelly · Cureus, 2025Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin
Camellia oleifera seed oil, Camellia sinensis seed oil · International Journal of Cosmetic Science, 2026Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
Ascorbyl glucoside · International Journal of Molecular Sciences, 2024Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study
Saccharomyces rice ferment filtrate, Pitera essence, Saccharomyces ferment filtrate, Saccharomyces rice bran ferment, Rice ferment filtrate sake ferment filtrate, Galactomyces ferment filtrate · Journal of Clinical Medicine, 2023Rapid and Visible Efficacy of a Dermocosmetic in Acne Patients With Fair Skin Phototypes: Results of a Randomized Split-Face Study
Zinc gluconate · Journal of Cosmetic Dermatology, 2026Effects of Malaysian thermal spring water as adjunct therapy for mild to moderate acne vulgaris - a prospective, randomised, controlled, split face study
Avene thermal spring water avene aqua, Water hungarian thermal water · The Medical Journal of Malaysia, 2024Pleiotropic effects of a Camellia sinensis leaf extract on in vitro and in vivo skin health characteristics
Camellia sinensis leaf water, Hadasei-3 complex, Black tea extract · International Journal of Cosmetic Science, 2025Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial
Tocopheryl acetate, Vitamin e tocopheryl acetate, Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021Efficacy and safety of a facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glaba root extract in the treatment of maskne: A randomized placebo-controlled study
Snail secretion filtrate · Journal of Cosmetic Dermatology, 2022Arginine-fructose-glucose from red ginseng extract reduces stiffness of keratin fiber in corneocyte of skin
Red ginseng extract · Skin Research and Technology, 2023Sterol-standardized phytopharmaceutical from ground cherry: Corticoid-like properties on human keratinocytes and fibroblasts and its effects in a randomized double-blind placebo-controlled clinical trial
Physalis angulata extract · Journal of Cosmetic Dermatology, 2019A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
Phas polyhydroxy acids · Cutis, 2004Mechanism and inhibitory effects of cactus (Opuntia dillenii) extract on melanocytes and its potential application for whitening cosmetics
Cactus extract · Scientific Reports, 2023The cutaneous effects of long-term use of Dead Sea mud on healthy skin: a 4-week study
Sea silt, Dead sea minerals · International Journal of Dermatology, 2021Anti-Aging Efficacy of Low-Molecular-Weight Polydeoxyribonucleotide Derived from Paeonia lactiflora
Sodium dna, Paeonia albiflora root extract · International Journal of Molecular Sciences, 2025Polydeoxyribonucleotide-spermidine nanoparticles: Preparation, characterization, and verification of skin anti-aging efficacy
Sodium dna · International Journal of Biological Macromolecules, 2025Potassium 4-Methoxysalicylate (4MSK) Exerts a Skin Lightening Effect by Acting on Melanocytes and Keratinocytes
Potassium methoxysalicylate · Journal of Cosmetic Dermatology, 2025Human Stem Cell-Derived Skin Progenitors Produce Alpha 2-HS Glycoprotein (Fetuin): A Revolutionary Cosmetic Ingredient
Glycoproteins · Journal of Drugs in Dermatology, 2016The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study
Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial
Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial
Montmorillonite, Bentonite, Volcanic clay, Moroccan lava clay, Bentonite clay, Super volcanic clay, Calcium bentonite clay · Journal of Cosmetic Dermatology, 2025Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial
Butyrospermum parkii butter shea butter, Oil tree, Shea butter, Saccharide isomerate · Lasers in Medical Science, 2025Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin
Portulaca oleracea extract, Lactobacillus portulaca oleracea extract ferment · Cutaneous and Ocular Toxicology, 2025Fruit acids and sodium hydroxide in the food industry and their combined effect with sodium lauryl sulphate: controlled in vivo tandem irritation study
Pronalen fruit acids, Sodium hydroxide · The British Journal of Dermatology, 2004Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters
Gluconolactone · Skin Research and Technology, 2023The harnessing potential of carboxymethyl beta glucan: A driver of skin repair
Magnesium carboxymethyl beta-glucan · International Journal of Cosmetic Science, 2026Effects of a Greek Yoghurt-based Complex on the Human Facial Skin Microbiome
Yogurt · In Vivo, 2026Augmented Skin Beneficial Effects of Thermus Thermophilus and Bacillus Subtilis Mixed-Culture Ferment Extract by Tripeptide GHK-Cu
Copper tripeptide-1 · Skin Research and Technology, 2026Anti-ageing activities of nanovesicles derived from Artemisia princeps in human dermal cells and human skin model
Artemisia princeps leaf powder, Artemisia princeps extract · Journal of Extracellular Biology, 2025Amaranth Oil for Dermatologic Conditions: Inflammation Control and Cytotoxicity Assessment in Skin-Related Cell Models-Preliminary Study
Rose oil flower · Molecules, 2026A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study
Saccharide isomerate · The Journal of Dermatological Treatment, 2025From Plant to Nano-Clinic: Advancing Wound Healing with Nano- Encapsulated Rosa damascena Callus Extract
Rosa damascena flower extract · Pharmaceutical Nanotechnology, 2026Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking
Palmitoyl tetrapeptide-7 · International Journal of Cosmetic Science, 2026Development of a nanotechnological hydrogel containing desonide nanocapsules in association with acai oil: design and in vivo evaluation
Euterpe oleracea fruit extract · Pharmaceutical Development and Technology, 2022Acai Oil-Based Organogel Containing Hyaluronic Acid for Topical Cosmetic: In Vitro and Ex Vivo Assessment
Euterpe oleracea fruit extract · Pharmaceutics, 2024Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial
Ascorbyl glucoside · Cureus, 2026Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population
Saccharide isomerate · Journal of Cosmetic Dermatology, 2023Skin Tolerance of Three Types of Dead Sea Mud on Healthy Skin: A Short-Term Study
Sea silt · Journal of Cosmetic Science, 2018Iontophoretic Delivery of Hyaluronic Acid Nanogel-Loaded Fermented Rice Extract Mitigates Skin Glycation
Lactobacillus rice ferment · International Journal of Nanomedicine, 2025The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color
Saccharomyces rice ferment filtrate, Galactomyces ferment filtrate · Skinmed, 2021Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study
Sodium laureth sulfate · International Journal of Pharmaceutics, 2026Structure/property comparisons of chemistries based on renewable 1,3-propanediol and petroleum-derived alkylene oxides
Propanediol · Journal of Cosmetic Science, 2017Simmondsia chinensis (jojoba) cake fermentation: A new, sustainable technology for advanced skin and scalp care ingredients
Lactobacillus ferment · International Journal of Cosmetic Science, 2026Hyaluronic Acid-like Skin Plumping and Radiance Benefits of a Porphyridium Sulfated Exopolysaccharide- and Natural PDRN-Rich Extract
Algae exopolysaccharides · Marine Drugs, 2026Dermatological Effects of a Beeswax-Pine Resin Mixture on Abdominal Skin: A Proof-of-Concept Study Supporting the Development of an Affordable Investigational Ostomy Pouching System in Low-Income Regions
Beeswax · Journal of Wound, Ostomy, and Continence Nursing, 2026A Promising Ultra-Small Unilamellar Carrier System for Enhanced Skin Delivery of α-Mangostin as an Anti-Age-Spot Serum
Garcinia mangostana peel extract · Pharmaceutics, 2022Biophysical effects of a natural peloid on normal skin
Sea silt hungarian mud · International Journal of Biometeorology, 2024Use of a Serum With the Infinite Glow® Device Improves Signs of Facial Aging: A Split-Face Case Report Using VISIA Analysis
Palmitoyl pentapeptide-4 · Cureus, 2026Two new lipoaminoacids with complementary modes of action: new prospects to fight out against skin aging
Palmitoyl glycine · International Journal of Cosmetic Science, 2010