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Perricone MD Rejuvenating Moisturizer for sensitive skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Perricone MD Rejuvenating Moisturizer

Average

  • AverageNormal Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for sensitive skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate suitability for normal skin, as glycerin and macadamia ternifolia seed oil provide hydration and enhance barrier resilience, though it lacks targeted ingredients for your specific concerns of redness and irritation.
  • While Tetrahexyldecyl Ascorbate offers antioxidant activity, the absence of ingredients like niacinamide or centella asiatica means the product primarily offers general skincare benefits rather than addressing your primary goals.
  • The product is safe for your sensitive skin, containing soothing rosemary leaf extract and avoiding harsh or prohibited ingredients.

How to apply

  • Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
  • Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
  • Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
  • You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
  • Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .

People Say

★4.6Overall rating based on 1.0k+ reviews

This moisturizer is praised for its rich texture that plumps, firms, and smooths aging or dry skin without greasiness. Many users report reduced fine lines and improved radiance. Some users experienced product pilling or sensitivity to the fragrance.

Highlights

  • Deeply hydrating Often Mentioned
    • “Keeps my skin moist without the acne.”
    • “Very rich and nourishing.”
    • “Replenishes fragile skin.”
  • Improves texture Often Mentioned
    • “Skin looks smoother, with no discoloration.”
    • “Visibly plumper, firmer, and smoother.”
    • “Skin feels better, smoother and brighter.”
  • Non-greasy formula Sometimes Noted
    • “It's non greasy, absorbs right in.”
    • “Absorbs quickly without any residual grease.”
    • “Not greasy or sticky.”
  • Reduces lines Sometimes Noted
    • “Plumps my skin to reduce the look of fine lines.”
    • “Targets deep wrinkles and creases.”
    • “Saw a reduction in the appearance of fine lines.”
  • Product pilling Sometimes Noted
    • “When I try to apply my liquid makeup over it it rolls up.”
    • “It all pealed away. It looked like a snow storm.”
    • “I do not really experience pilling unless I use too much.”
  • Fragrance sensitivity Rarely Noted
    • “A few reviewers found the fragrance too strong.”
    • “Unfortunately had an allergic reaction.”
    • “Experienced minor irritation.”
  • White cast Rarely Noted
    • “Leaves this white flaky texture on my face.”
    • “Had to really blend so it didn't appear to leave a white cast.”
    • “Doesn't leave a whitecast (after 7 days).”

Sources: lovi.care, perriconemd.com, lovelyskin.com, walmart.com, ipsy.com, nordstrom.com, and more

Questions and answers

How well does Perricone MD Rejuvenating Moisturizer work for sensitive skin?

Perricone MD Rejuvenating Moisturizer works as an average fit for sensitive skin because it provides basic hydration while lacking targeted ingredients for redness and irritation. A product of this type needs soothing ingredients like fermented centella asiatica, cica ceramide, and nourishing oils to effectively calm and protect sensitive skin.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this cream a good fit for sensitive skin?

Glycerin and macadamia seed oil help hydrate and keep your skin resilient, while rosemary leaf extract safely soothes. However, because this cream lacks ingredients that target redness and irritation, a product of this type needs soothing ingredients like fermented centella asiatica and cica ceramide to truly fit sensitive skin.

Clinical, Cosmetic and Investigational Dermatology, 2017

What does Acyl-Glutathione do for sensitive skin?

Acyl-glutathione helps protect sensitive skin by reducing oxidative stress and fighting environmental damage, though a product for this skin type also needs soothing ingredients to calm irritation and strengthen the skin barrier.

Journal of the European Academy of Dermatology and Venereology, 2024Journal of Cosmetic Dermatology, 2026

What does Vitamin C do for sensitive skin?

For sensitive skin, Vitamin C helps calm redness and evens out dark spots while improving overall skin quality and radiance. Daily use is generally well-tolerated and may help protect against environmental stress.

Journal of Cosmetic Dermatology, 2019Journal of Cosmetic Dermatology, 2024

Where does it go in a skincare routine for sensitive skin?

This moisturizing treatment goes in the evening routine after your toner and before your moisturizer. It is safe for sensitive skin, though a product of this type needs calming ingredients like niacinamide or centella asiatica to better handle redness and irritation.

Can I use this cream with retinol, and in what order?

This cream is safe to use with retinol, applying it after your retinol treatment in your evening routine. A product of this type needs calming ingredients like niacinamide or centella asiatica to properly soothe redness and irritation on sensitive skin.

How often should I use it?

This moisturizer works well on your sensitive skin, though a product of this type needs calming ingredients like niacinamide or centella asiatica to better handle redness and irritation.

Can this cream clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to clog pores or cause breakouts for sensitive skin, as it has a safe profile and avoids harsh ingredients. However, because it is an average fit for your skin, a product of this type needs soothing and calming ingredients like niacinamide or centella asiatica to properly comfort redness and irritation.

Can I use it around the eyes or on my body?

You can use this moisturizer on your face and body, though it is not specifically formulated for the delicate skin around the eyes. While the product is safe for sensitive skin and provides good general hydration, sensitive skin prone to redness and irritation needs targeted ingredients like niacinamide or centella asiatica to properly calm and soothe those specific concerns.

Surgical and Radiologic Anatomy, 2002

Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, citronellol, limonene, and linalool). Cetearyl alcohol is a fatty alcohol, which soften the skin.

What the research says

Why other moisturizers fit sensitive skin better

  • A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.

    Journal of Cosmetic Dermatology, 2024

  • Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

    American Journal of Clinical Dermatology, 2002

  • A dexpanthenol-containing cream accelerated skin barrier repair, increased stratum corneum hydration, reduced skin roughness, and decreased skin redness compared to vehicle and untreated controls in sodium lauryl sulphate-irritated skin.

    The Journal of Dermatological Treatment, 2002

Ingredients

Water, Ethylhexyl Palmitate, Glycerin, Dimethicone, Cetearyl Alcohol, Glyceryl Stearate, Polysorbate 60, Palmitoyl Glycine, S-Palmitoylglutathione, Tetrahexyldecyl Ascorbate, Peg-100 Stearate, Ribose, Lactic Acid, Linum Usitatissimum Seed Oil, Macadamia Ternifolia Seed Oil, Polyglyceryl-10 Stearate, Ethylhexylglycerin, Salvia Hispanica Seed Oil, Tocopherol, Helianthus Annuus Seed Oil Sunflower Seed Oil, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Polyacrylamide, Sodium Acrylates Copolymer, Polysilicone-11, Hydrogenated Polyisobutene, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Parfum, Citronellol, Hydroxycitronellal, Limonene, Linalool

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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How does it fit your skin?

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