Perricone MD Rebalancing Elixir for dry sensitive skin
Cannabidiol
Mushroom Complex
Cherimoya Fruit Extract
Capryloyl Glycine
Sodium Pca
High
- HighDry Skin Fit
- HighEffectiveness
- ExcellentSafety
A great choice for dry sensitive skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Excellent suitability for your dry and sensitive skin as the combination of Sodium PCA and Glycerin provides essential hydration and supports your skin barrier function, while Cannabidiol and Annona Cherimola Fruit Extract soothe irritation.
- The inclusion of Cannabis Sativa Seed Oil offers emollient benefits, further enhancing nourishment for your dry skin.
- The product is safe for your skin, featuring a gentle formulation free from harsh ingredients and enriched with soothing components like mushroom extracts.
How to apply
- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
People Say
★4.5Overall rating based on 800+ reviewsMost users find it provides lightweight hydration that absorbs quickly without feeling heavy, leading to improved skin balance and texture. A moderate number of users feel the product is too expensive for the results, and a low number dislike the natural scent or do not see dramatic anti-aging effects.
Highlights
Soothes sensitive skin Mostly Mentioned
- “soothed irritation instantly”
- “no stinging on application”
- “relief was real”
Lightweight hydration Often Mentioned
- “absorbs super quickly”
- “skin feels hydrated not oily”
- “lightweight moisture boost”
- “perfect for oily/combo skin”
Good for layering Sometimes Noted
- “makeup went right over it”
- “great base for serums”
- “didn't pill under moisturizer”
- “compatible with hyaluronic acid”
Improves skin texture Sometimes Noted
- “softening effect overall”
- “skin shines bright”
- “balanced my pH”
- “smooths texture perfectly”
Expensive for results Sometimes Noted
- “doesn't justify the price”
- “very expensive for a toner”
- “expected more for the cost”
- “pricey investment”
Not a miracle worker Rarely Noted
- “didn't do miracles”
- “just okay hydration”
- “didn't see major changes”
- “good but not amazing”
Product availability issues Rarely Noted
- “hard to find stock”
- “range has been discontinued”
- “replaced by new line”
- “out of stock everywhere”
Unpleasant natural scent Rarely Noted
- “organic almost gamey scent”
- “smells like mushrooms”
- “scent lingers slightly”
- “weird natural smell”
Sources: lovi.care, perriconemd.com, macys.com, influenster.com, lookfantastic.com, menstylefashion.com, and more
Questions and answers
What makes Perricone MD Rebalancing Elixir a great fit for dry sensitive skin?
Perricone MD Rebalancing Elixir is a great fit because ingredients like sodium PCA and glycerin deliver essential hydration and support your skin barrier, while cannabidiol and cherimoya fruit extract help soothe irritation. Additionally, cannabis sativa seed oil nourishes dry skin, and the gentle formula is free from harsh ingredients.
Clinical, Cosmetic and Investigational Dermatology, 2017Journal of Cosmetic Dermatology, 2023
Which ingredients make this elixir a good fit for dry sensitive skin?
This elixir is a great fit because Sodium PCA and glycerin provide essential hydration and support your skin barrier, while cannabidiol and cherimoya fruit extract help calm irritation. Cannabis Sativa seed oil also offers soothing nourishment to keep dry skin soft and comfortable.
What does Cannabidiol do for dry sensitive skin?
Cannabidiol helps soothe dry sensitive skin by calming irritation and improving hydration and skin barrier function. It is unlikely to cause irritation and may help reduce redness and discomfort.
Journal of Cosmetic Dermatology, 2023International Journal of Dermatology, 2015
What does Mushroom Complex do for dry sensitive skin?
Mushroom Complex helps calm dry and sensitive skin while easing irritation because of its anti-inflammatory properties. It also protects skin with antioxidants, though a product for this skin type needs extra rich, soothing ingredients to lock in moisture.
Where does this elixir go in a skincare routine for dry sensitive skin?
This treatment goes in the evening routine after cleansing and a soothing toner, and before your moisturizer. It is also used in the evening in weekly routines after a nourishing mask.
Can I use this elixir with retinol, and in what order?
You can use this treatment with retinol by applying the elixir first to hydrate and calm your dry skin before layering your retinol on top. This gentle formula helps reduce potential irritation while keeping your skin soft and nourished.
How often should I use this elixir?
You can use this treatment in the evening as part of your routine. It is a great fit for your dry sensitive skin because it provides essential hydration and helps calm irritation.
Can this elixir clog pores, cause breakouts or purging for dry sensitive skin?
This elixir is unlikely to clog pores or cause breakouts on dry sensitive skin, as it features a gentle formula free from heavy, pore-blocking ingredients. Its hydrating components help keep skin balanced without overwhelming it.
Is this elixir fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical application of an anti-aging gel containing EPA and CBD reduced inflammatory agents, decreased crow's feet and fine line wrinkle volume, reduced the subepidermal low-echogenic band by 8.8%, and increased skin hydration by 31.2% and elasticity by 25.6% in 33 participants over 56 days compared to baseline.
Journal of Cosmetic Dermatology, 2023Topical nano-cannabidiol cream reduced UV-A-induced epidermal hyperplasia, nuclear DNA base lesions, and mitochondrial DNA deletions compared with vehicle in nineteen participants.
Journal of the American Academy of Dermatology, 2024Daily application of a novel retinol and cannabidiol combination topical improved global skin quality across 13 domains, including visible pores, dehydration, surface roughness, and static and dynamic wrinkles, in 10 patients with facial skin imperfections.
Aesthetic Surgery Journal. Open Forum, 2022Topical application of carboxymethylcellulose/chitosan hydrogel loaded with cannabidiol reduced inflammation and increased collagen production in radiation-combined wound skin injury in mice.
Phytomedicine, 2025Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy.
Journal of Cosmetic Dermatology, 2021Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups.
Dermatology and Therapy, 2023Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment.
The Journal of Dermatology, 2022Topical application of a formulation containing capryloyl glycine 4% significantly decreased hair density, median hair length, and terminal hair density on the forearms compared to placebo in female patients with hypertrichosis after 120 days.
Journal of Cosmetic Dermatology, 2021A novel natural carrier-free assembled gel composed of sodium pyrrolidone carboxylate and baicalin alleviates UVB-induced skin photodamage by scavenging reactive oxygen species, protecting mitochondria, restoring oxidative homeostasis, inhibiting inflammatory responses, and regulating collagen-related proteins.
Biomaterials Advances, 2026
Ingredients
Water, 1,2-Hexanediol, Sodium Pca, Triethyl Citrate, Propanediol, Capryloyl Glycine, Glycerin, Annona Cherimola Fruit Extract, Cannabidiol, Ganoderma Lucidum Stem Extract Mushroom Stem Extract, Grifola Frondosa Fruiting Body Extract, Sodium Bicarbonate, Caprylhydroxamic Acid, Sodium Hydroxide, Citric Acid, Cannabis Sativa Glycereth-8 Esters Seed Oil, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sodium Citrate, Lentinus Edodes Mycelium Extract, Sodium Dehydroacetate, Phenylpropanol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-
Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-
Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-
Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-
Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-
Medical Board
Cosmetic chemist, SCS, IFSCC member
-
Medical Board, Medical Advisor
Dermatology MD
-
Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-
Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.