MEDIHEAL Collagen Ampoule Pad for acne-prone skin
Collagen Extract
Adenosine
Ceramide Np
Betaine
Lactobacillus FermentHigh
- HighCombination Skin Fit
- AverageEffectiveness
- HighSafety
A great choice for acne-prone skin; a few moisturizers fit it even better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- This formulation offers high suitability for your combination skin, with glycerin and hydroxyethyl urea providing excellent humectant action to hydrate the skin.
- While collagen extract and multiple peptides work to improve skin elasticity and offer general soothing benefits, the absence of ingredients like salicylic acid means it does not directly target your acne, blemishes, and breakouts.
- The safety profile is excellent, with no risks of irritation due to the absence of prohibited or harsh ingredients for your skin.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
People Say
★4.8Overall rating based on 1.0k+ reviewsBased on a very large amount of data, users consistently praise these pads for their ability to deeply hydrate and plump the skin, often describing a "glass skin" effect that serves as an excellent base for makeup. They are highly effective for soothing redness and improving texture on sensitive skin. Some users note a sticky finish and a fragrance that may not suit everyone.
Highlights
Deep hydration & plumping Mostly Mentioned
- “Skin feels plump and hydrated”
- “fills loose skin with elasticity”
- “fine lines look less noticeable”
Generous essence Often Mentioned
- “Pads are saturated”
- “soaked in potent serum”
- “holds so much product”
Versatile & convenient Often Mentioned
- “Great prep before makeup”
- “use as mini sheet masks”
- “super convenient for quick skincare”
High-quality pad Sometimes Noted
- “Thin and weightless”
- “sticks really well”
- “super soft cotton pads”
Soothing & cooling Sometimes Noted
- “Calms redness”
- “cools off my face”
- “soothing to sensitive skin”
Noticeable fragrance Sometimes Noted
- “Scent is kind of overpowering”
- “faintly floral or soapy”
- “smell is average”
Lack of immediate glow Rarely Noted
- “Not as glowy as I thought”
- “didn't notice any improvement”
- “just average”
Price and value Rarely Noted
- “Feels extortionate per pad”
- “wasteful to throw out”
- “price point is the only downside”
Sticky residue Rarely Noted
- “Super sticky”
- “dried down in a way I wasn't expecting”
- “feels a little sticky”
Sources: lovi.care, iherb.com, global.oliveyoung.com, stylevana.com, reddit.com, youtube.com, and more
Questions and answers
What makes MEDIHEAL Collagen Ampoule Pad a great fit for acne-prone skin?
This product is a great fit for your acne-prone skin because it hydrates deeply with ingredients like glycerin while offering soothing benefits, and it has an excellent safety profile without harsh or irritating ingredients.
Which ingredients make this treatment a good fit for acne-prone skin?
What does Collagen Extract do for acne-prone skin?
Collagen Extract is unlikely to clog pores and may help soothe redness and keep acne-prone skin calm. Because this type of product is a poor fit for oily skin, acne-prone skin needs lightweight formulas with soothing ingredients and gentle acne-fighting extracts to stay clear and smooth.
What does Adenosine do for acne-prone skin?
Adenosine helps calm acne-prone skin by reducing redness and swelling. It is unlikely to clear breakouts on its own, so acne-prone skin needs ingredients that clear pores and balance oil, like salicylic acid.
Where does this treatment go in a skincare routine for acne-prone skin?
This treatment goes in your evening routine as a step after cleansing and toning, and before moisturizing. Lovi routines put treatments in the evening for simplicity and extra safety around sun exposure.
Can I use this treatment with retinol, and in what order?
Yes, you can use this treatment with retinol by applying it right before your retinol step to help keep your skin calm and hydrated. This approach is unlikely to cause irritation because the product has a very gentle safety profile and lacks harsh ingredients.
How often should I use this treatment?
You can use this treatment in your evening routine, applying it once a day or a few times a week as your skin adjusts. The formula has an excellent safety profile with no harsh ingredients, so it is unlikely to cause irritation.
Health Science Reports, 2021Journal of Drugs in Dermatology, 2015
Can this treatment clog pores, cause breakouts or purging for acne-prone skin?
This treatment is unlikely to clog pores or cause breakouts on acne-prone skin because it has an excellent safety profile with no harsh ingredients. While it hydrates and soothes, it lacks ingredients like salicylic acid, so it does not directly target active breakouts.
Can I use this treatment around the eyes or on my body?
You can safely use this moisturizing treatment around the eyes and on the body because it features a very safe formula with no harsh ingredients. The thin skin around the eyes and various body areas readily tolerate its hydrating ingredients, such as glycerin and betaine, which help keep skin soft and smooth without irritation.
Surgical and Radiologic Anatomy, 2002Clinical, Cosmetic and Investigational Dermatology, 2017
Is this treatment fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Soaps containing betaine caused the least skin irritation compared to other tested soaps in twenty-eight healthy subjects, though irritation did not decrease with increasing concentrations of betaine.
Skin Research and Technology, 2003Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris.
Journal of Cosmetic Dermatology, 2022Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks.
International Journal of Molecular Sciences, 2022Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers.
Marine Drugs, 2023Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months.
The Journal of Dermatology, 2008Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants.
International Journal of Molecular Sciences, 2026Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts.
International Journal of Molecular Sciences, 2021Topical dry mouth products containing olive oil, betaine, and xylitol significantly increased unstimulated whole salivary flow rates, reduced xerostomia complaints, and improved quality of life in adults with polypharmacy-induced xerostomia compared to their normal routine care, with no clinically significant adverse events.
Journal of Oral Rehabilitation, 2007A combination of Aloe barbadensis leaf extract and trimethylglycine in a 1:1 mass ratio synergistically increased aquaporin 3 expression by up to 380% in keratinocytes and safely improved skin hydration in healthy volunteers.
Molecules, 2024Mixed surfactant systems of sodium dodecyl sulfate and dimethyl dodecyl amido betaine significantly reduce acute skin irritation potential in human volunteers compared with the individual surfactants, demonstrating that irritation potential cannot be predicted by simple summation.
Food and Chemical Toxicology, 1998Probiotic-derived lotion successfully reduced inflammatory acne lesion counts and erythema index comparably to 2.5% benzoyl peroxide in patients with mild-to-moderate acne vulgaris, while causing fewer side effects.
Journal of Cosmetic Dermatology, 2022Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers.
International Journal of Medical Sciences, 2021Lactobacillus plantarum extracellular vesicles modulated extracellular matrix related gene expression in vitro and suppressed wrinkle formation and pigmentation in clinical trials.
Current Issues in Molecular Biology, 2022
Ingredients
Water, Glycerin, Glycereth-26, 1,2-Hexanediol, Diphenyl Dimethicone, Triethylhexanoin, Betaine, Hydroxyacetophenone, Hydrogenated Lecithin, Polyglyceryl-10 Oleate, Hydroxyethyl Urea, Dipotassium Glycyrrhizate, Sodium Citrate, Allantoin, Octyldodeceth-16, Xanthan Gum, Hydroxyethylcellulose, Collagen Extract, Adenosine, Citric Acid, Disodium Edta, Olea Europaea Oil Fruit Olive Oil Fruit, Butylene Glycol, Pelargonium Graveolens Oil Flower, Lavandula Angustifolia Oil Lavender Oil, Anthemis Nobilis Oil Flower, Citrus Aurantium Dulcis Peel Oil, Juniperus Mexicana Oil, Mangifera Indica Fruit Extract, Lactobacillus Ferment, Ceramide Np, Extract Milk Protein, Caprylyl Glycol, Tripeptide-1, Acetyl Hexapeptide-8, Copper Tripeptide-1, Palmitoyl Tripeptide-1, Palmitoyl Pentapeptide-4
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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