MEDI-PEEL Red Lacto Collagen Cleansing Oil for acne-prone skin

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Questions and answers

What the research says

• Topical application of an emollient emulsion containing 15.0% caprylic/capric triglyceride doubled the amount of urocanic acid isomers and increased skin hydration with reduced transepidermal water loss in healthy subjects, though it did not prevent ultraviolet-induced urocanic acid isomerization.

  Life, 2023

• Asiatic acid-loaded solid lipid microparticles stabilized with poloxamer-188 reduced porphyrin intensity, enhanced skin barriers, and improved skin hydration and brightness in fifteen participants with mild-to-moderate acne.

  International Journal of Pharmaceutics, 2024

• Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers.

  International Journal of Medical Sciences, 2021

• Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.

  Molecules, 2023

• Novel beads of alpha-cyclodextrin and soybean oil achieved high adapalene encapsulation (>96%), demonstrated good skin tolerance without adverse reactions in human volunteers, and provided stratum corneum penetration in pig skin comparable to commercial gel and cream formulations.

  Pharmaceutical Research, 2008

• Probiotic-derived lotion successfully reduced inflammatory acne lesion counts and erythema index comparably to 2.5% benzoyl peroxide in patients with mild-to-moderate acne vulgaris, while causing fewer side effects.

  Journal of Cosmetic Dermatology, 2022

• Lactobacillus plantarum extracellular vesicles modulated extracellular matrix related gene expression in vitro and suppressed wrinkle formation and pigmentation in clinical trials.

  Current Issues in Molecular Biology, 2022

• Topical application of a postbiotic Saccharomyces and Lactobacillus ferment complex for 28 days significantly modulated the scalp microbiome and achieved a 100% sensitive scalp syndrome alleviation effect in Chinese women with sensitive scalp syndrome.

  Clinical, Cosmetic and Investigational Dermatology, 2023

• Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris.

  Journal of Cosmetic Dermatology, 2022

• Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks.

  International Journal of Molecular Sciences, 2022

• Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers.

  Marine Drugs, 2023

• Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.

  Journal of Alternative and Complementary Medicine, 2020

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

Why other pre-cleansers fit acne-prone skin better

• Mentha arvensis oil in this pre-cleanser

  Topical menthol induced significant pain, cold sensations, punctate and cold hyperalgesia, and increased cutaneous perfusion in 10 subjects compared to ethanol control, acting as a human model for cold pain by sensitizing peripheral cold C nociceptors and activating cold-specific A delta fibres.

  Brain, 2004

Ingredients

Glycine Soja Oil Soybean Oil, Sorbeth-30 Tetraoleate, Caprylic Capric Triglyceride, Jojoba Seed Oil, Olea Europaea Oil Fruit Olive Oil Fruit, Candida Bombicola Glucose Methyl Rapeseedate Ferment, Mentha Arvensis Oil Leaf, Prunus Armeniaca Kernel Oil Apricot Kernel Oil, Tocopheryl Acetate, Oenothera Biennis Oil, Barosma Betulina Leaf Extract, Rice Germ Oil, Rosa Damascena Flower Water, Vitis Vinifera Seed Oil Grape Seed Oil, Limnanthes Alba Seed Oil, Argania Spinosa Kernel Oil, Centella Asiatica Leaf Extract, Camellia Sinensis Leaf Extract, Gardenia Florida Fruit Extract, Schisandra Chinensis Fruit Extract, Curcuma Longa Root Extract, Lithospermum Erythrorhizon Root Extract, Helianthus Annuus Seed Oil Sunflower Seed Oil, Carapa Guaianensis Seed Oil, Water, Lactobacillus Ferment, Butylene Glycol, Xylitylglucoside, Anhydroxylitol, Xylitol, Diospyros Kaki Leaf Extract, Vitis Vinifera Fruit Extract Grape Fruit Extract, 1,2-Hexanediol, Coffea Arabica Seed Extract Coffee Seed Extract, Carthamus Tinctorius Flower Extract, Polygonum Cuspidatum Root Extract, Zanthoxylum Piperitum Fruit Extract, Chestnut Shell Extract, Glucose, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Proline, Valine, Threonine, Isoleucine, Pinus Palustris Leaf Extract, Ulmus Davidiana Root Extract, Pueraria Lobata Root Extract, Oenothera Biennis Flower Extract, Histidine, Methionine, Cysteine, Ethylhexylglycerin, Hydrolyzed Collagen

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.