Medi-Peel Hyal Kombucha Tea-Tox Toner for sensitive skin

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Questions and answers

What the research says

• Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.

  Molecules, 2023

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.

  Journal of Alternative and Complementary Medicine, 2020

• Optimized transfersomes loaded with epigallocatechin-3-gallate and hyaluronic acid increased cell viability while reducing lipid peroxidation, intracellular ROS, and MMP expression in HaCaT cells, and exhibited higher skin permeation and deposition compared to plain EGCG.

  Drug Delivery, 2017

• Kombucha Yerba Mate ferments after 14 and 21 days of fermentation showed about a 40% inhibition of lipoxygenase, collagenase, and elastase enzymes, long-lasting skin hydration, and increased cell viability on keratinocyte and fibroblast cell lines compared to unfermented extracts.

  Scientific Reports, 2021

• Fermentation of grape stems extract using a Scoby consortium for 10 and 20 days increases phenolic content and antioxidant activity, and when added to model cosmetic creams, improves skin hydration and reduces transepidermal water loss.

  International Journal of Cosmetic Science, 2023

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline.

  Experimental Dermatology, 2008

• Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream.

  International Journal of Cosmetic Science, 2008

Ingredients

Saccharomyces Xylinum Black Tea Ferment, Water, Cetylethylhexanoate, Hydrogenated Poly C6-14 Olefin, 1,2-Hexanediol, Niacinamide, Propanediol, Glycerin, Butylen Glycol, Caprylic Capric Triglyceride, Decyl Glucoside, Carbomer, Saccharomyces Rice Bran Ferment, Adansonia Digitata Seed Oil, Hydrogenated Lecithin, Camellia Flower Extract, Citrus Unshiu Peel Extract, Madecassoside, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Ceramide Np, Ceramide Ns, Ceramide, Ceramide Op, Ceramide Ap, Sodium Hyaluronate, Hydrolyzed Glycosaminoglycan, Sodium Hyaluronate Crosspolymer, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Sodium Acetylated Hyaluronate, Rosa Damascena Flower Water, Pyrus Communis Fruit Extract, Prunus Persica Fruit Extract, Jasmine Flower Water, Hedera Helix Stem Extract Leaf, Cucumis Melo Fruit Extract, Tocopheryl Acetate, Cyanocobalamin, Caprylyl Glycol, Magnesium Chloride, Benzyl Glycol, Polysorbate 60, Ethylhexylglycerin, Adenosine, Caramel, Pentylene Glycol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.