LANEIGE Radian-C Vitamin Spot Serum 15.2% for acne-prone skin
Ascorbic Acid
Niacinamide
Tranexamic Acid
Glutathione
Licorice Root ExtractSuperior
- SuperiorCombination Skin Fit
- SuperiorEffectiveness
- ExcellentSafety
One of the best serums for acne-prone skin.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Excellent suitability for your combination skin and acne concerns is provided by the high concentrations of Ascorbic Acid and 3-O-Ethyl Ascorbic Acid, which effectively brighten and even your skin tone while offering antioxidant and anti-inflammatory benefits. Niacinamide and Tranexamic Acid further support these actions by regulating melanogenesis and reducing inflammation, contributing to clearer, more radiant skin.
- The inclusion of Tocopherol and Centella Asiatica Stem Extract Flower Leaf ensures a soothing experience, minimizing any potential irritation for your combination skin.
- This formula is safe for your skin, with no harsh ingredients and a focus on soothing components.
How to apply
- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
People Say
★4.0Overall rating based on 100+ reviewsBased on limited data, users frequently praise this serum for effectively fading dark spots and brightening skin tone, noting it is gentle enough for sensitive skin. A significant number of reviewers report issues with the product oxidizing quickly, and some find the scent unpleasant or the finish sticky. There are also moderate reports of packaging issues and the product quantity being small for the price.
Highlights
Brightens skin tone Often Mentioned
- “brightens skin tone”
- “gives radiance”
- “skin looks even toned”
Fades dark spots Often Mentioned
- “fades acne scars”
- “lightens pigmentation”
- “helps with blemishes”
Rapid oxidation Often Mentioned
- “oxidizes quickly”
- “turns yellow/brown”
- “short shelf life”
Fast absorption Sometimes Noted
- “absorbs quickly”
- “lightweight texture”
- “watery consistency”
Gentle formula Sometimes Noted
- “good for sensitive skin”
- “no tingling”
- “gentle formula”
Packaging issues Sometimes Noted
- “leaked in transit”
- “messy dropper”
- “exploded in box”
Small quantity Sometimes Noted
- “tiny bottle”
- “expensive for size”
- “finished quickly”
Sticky/oily finish Sometimes Noted
- “sticky finish”
- “oily residue”
- “feels greasy”
Unpleasant scent Sometimes Noted
- “salty/sour scent”
- “smells like broth”
- “weird vitamin smell”
Sources: lovi.care, sephora.co.th, sephora.sg, femaledaily.com, projectvanity.com, ohmystellar.com, and more
Questions and answers
What makes LANEIGE Radian-C Vitamin Spot Serum one of the best fits for acne-prone skin?
This serum is one of the best fits for acne-prone skin because high concentrations of Ascorbic Acid and 3-O-Ethyl Ascorbic Acid brighten uneven skin tone while offering antioxidant and anti-inflammatory benefits. Niacinamide and Tranexamic Acid further support this by reducing inflammation for clearer skin, while soothing ingredients like Centella Asiatica Stem Extract minimize any potential irritation.
Which ingredients make this serum a good fit for acne-prone skin?
This serum is a great fit because of Ascorbic Acid, 3-O-Ethyl Ascorbic Acid, Niacinamide, and Tranexamic Acid, which help brighten skin and reduce inflammation. Tocopherol and Centella Asiatica Stem Extract Flower Leaf are also included to calm acne-prone skin and minimize irritation.
What does Vitamin C do for acne-prone skin?
Vitamin C helps brighten skin, smooth out uneven tones, and fade dark spots left behind by breakouts. It is also packed with antioxidants that may help protect acne-prone skin from everyday environmental stress.
Journal of Cosmetic Dermatology, 2023Journal of Drugs in Dermatology, 2024
What does Niacinamide do for acne-prone skin?
Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Where does this serum go in a skincare routine for acne-prone skin?
This treatment serum goes in the evening routine after cleansing and before moisturizing, though some can also be used in the morning or twice a day. It is very well suited for acne-prone skin because it combines powerful brightening vitamins with soothing ingredients that help keep your skin clear while minimizing irritation.
Can I use this serum with retinol, and in what order?
You can use this treatment in your routine with retinol by applying the retinol first and following with this serum, or by using retinol at night and this serum in the morning. This formula has a very good safety profile with soothing ingredients that are unlikely to cause irritation when combined thoughtfully.
How often should I use this serum?
This treatment serum works best in your evening routine, applied once a day. Lovi routines place treatments in the evening for simplicity and extra safety around sun exposure.
Can this serum clog pores, cause breakouts or purging for acne-prone skin?
This serum is unlikely to clog pores or cause breakouts for acne-prone skin because it relies on soothing and brightening ingredients like vitamin C, niacinamide, and centella extract that help calm redness and clear uneven tone. It also has a safe profile with no harsh components that typically trigger irritation or congestion.
The British Journal of Dermatology, 2002Journal of Cosmetic Dermatology, 2020
Is this serum fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (limonene, parfum, linalool, and citral).
What the research says
Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.
The British Journal of Dermatology, 2002A multi-component dissolving microneedle patch loaded with glabridin, 3-O-ethyl-L-ascorbic acid, and tranexamic acid effectively reduced chloasma and age spots while demonstrating safety in clinical evaluation, alongside significant antioxidant, anti-tyrosinase, and melanin-reduction effects in vitro and in vivo.
Polymers, 2023A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.
Journal of Cosmetic Dermatology, 2020Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.
Indian Journal of Pharmaceutical Sciences, 2016Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.
Journal of Cosmetic Dermatology, 2022Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls.
Journal of the European Academy of Dermatology and Venereology, 2024Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2014Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity.
The Journal of Clinical and Aesthetic Dermatology, 2025Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism.
Evidence-based Complementary and Alternative Medicine, 2015Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo.
Experimental Dermatology, 2015Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide.
Advanced Science, 2025
Ingredients
Water, Ascorbic Acid, Propanediol, Dimethicone, Dipropylene Glycol, Tromethamine, 3-O-Ethyl Ascorbic Acid, Squalane, Panthenol, Sodium Chloride, Acetyl Glucosamine, Limonene, Caffeine, Sodium Hyaluronate, Sodium Sulfite, Disodium Edta, Glutathione, Parfum, Gardenia Florida Fruit Extract, Dextrin, Linalool, Citral, Butylene Glycol, Arginine, Xanthan Gum, Niacinamide, Tranexamic Acid, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Tocopherol, Methyl Trimethicone, Carthamus Tinctorius Seed Oil, 1,2-Hexanediol, Ethylhexylglycerin, Centella Asiatica Stem Extract Flower Leaf
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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