Goldfaden MD Radical Difference for combination skin
Sodium Hyaluronate
Aspalathus Linearis Extract
Lactobacillus Acerola Cherry Ferment
Saccharomyces Zinc Ferment
Saccharomyces Magnesium Ferment
Average
- HighCombination Skin Fit
- AverageEffectiveness
- HighSafety
Works for combination skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate hydration and antioxidant benefits for your combination skin, as sodium hyaluronate plumps and aspalathus linearis extract provides antioxidant support, though it is not specifically targeted for oily shine.
- The inclusion of saccharomyces ferments aids in barrier repair, which is beneficial for maintaining overall skin balance on your combination skin.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
Questions and answers
How well does Radical Difference work for combination skin?
Goldfaden MD Radical Difference works decently for combination skin by offering moderate hydration and antioxidant support, though other products fit it better because they manage oily shine more effectively. Treatments that work best for this skin need ingredients like niacinamide, propolis, or zinc PCA to regulate oiliness and provide optimal hydration without causing excess shine.
Which ingredients make this treatment a good fit for combination skin?
Sodium hyaluronate and aspalathus linearis extract make this treatment a good fit by offering moderate hydration and antioxidant support, while saccharomyces ferments help keep your skin balanced. Treatments that fit combination skin even better need ingredients like niacinamide, propolis, or zinc PCA to help control oily shine while keeping dry areas comfortable.
What does Hyaluronic Acid do for combination skin?
Hyaluronic acid is a great fit for combination skin because it quenches dry areas with a boost of hydration while keeping oily zones balanced. Regular use helps smooth out fine lines and makes your skin feel soft and plump without causing irritation.
Dermatology and Therapy, 2021Journal of Drugs in Dermatology, 2011
What does Roobos Extract do for combination skin?
Rooibos extract helps calm combination skin and protects it against sun stress. It acts as an antioxidant to keep your skin feeling smooth and balanced.
Where does this treatment go in a skincare routine for combination skin?
This treatment goes in the evening routine after cleansing and before moisturizing, and can also be used during the weekly routine. A product of this type needs moderate hydration, antioxidant support, and ingredients that help maintain skin balance without adding oily shine for combination skin.
Can I use it with retinol, and in what order?
You can use this treatment with retinol by applying the retinol first and following with this product, or by using your retinol at night and this treatment in the morning. This product helps maintain skin balance and is unlikely to cause irritation, making it generally compatible with a retinol routine. A product for combination skin used alongside retinol also needs ingredients that target oily shine while keeping the skin calm and hydrated.
How often should I use this treatment?
Use this treatment in your evening routine, applying it after your cleansing toner and before your moisturizer. Combination skin needs products that provide balanced hydration and antioxidant support while also helping control oily shine.
Can it clog pores, cause breakouts or purging for combination skin?
Goldfaden MD Radical Difference is unlikely to clog pores or cause breakouts on combination skin because it is free of harsh, heavy ingredients. However, a product for this skin type also needs ingredients that help control oily shine, which this treatment does not specifically target.
Is this treatment fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.
Dermatologic Therapy, 2022Optimized transfersomes loaded with epigallocatechin-3-gallate and hyaluronic acid increased cell viability while reducing lipid peroxidation, intracellular ROS, and MMP expression in HaCaT cells, and exhibited higher skin permeation and deposition compared to plain EGCG.
Drug Delivery, 2017Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine.
Journal of Pharmacy & Pharmaceutical Sciences, 2015Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Ginkgo formulation increased skin moisturization by 27.88% and smoothness by 4.32% while reducing roughness by 0.4% and wrinkles by 4.63%, and significantly improved skin moisturization compared to the tea and rooibos formula.
International Journal of Cosmetic Science, 2010The addition of Aspalathus linearis extracts to topical sunscreen formulas containing OMC and BMDBM increased protection factors by up to 50% and protected the filters against photodegradation under radiation doses up to 14.4 standard erythemal doses.
Photochemical & Photobiological Sciences, 2026The combination of fermented and unfermented Aspalathus linearis extracts showed a synergistic photoprotective effect on Normal Human Dermal Fibroblast survival after UVB radiation, which further improved when combined with Polypodium leucotomos extract.
International Journal of Molecular Sciences, 2025Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline.
Experimental Dermatology, 2008
Why other serums fit combination skin better
Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo.
BioMed Research International, 2022A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.
Journal of Cosmetic Dermatology, 2024
Ingredients
Water, Sodium Hyaluronate, Aspalathus Linearis Extract, Lactobacillus Acerola Cherry Ferment, Saccharomyces Zinc Ferment, Saccharomyces Magnesium Ferment, Saccharomyces Iron Ferment, Saccharomyces Silicon Ferment, Phenoxyethanol, Ethylhexylglycerin
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Dr. Sofía Perea Pérez, MD, MSc
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Elina Nazarenko, MD
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Victoria Derkova, MS
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