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glymed+ Oxygen Cream for dry sensitive skin

Rated by Lovi 路 Unbiased, science-based skincare AI trained on real user outcomes

glymed+ Oxygen Cream

Average

  • HighDry Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for dry sensitive skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate suitability for your dry and sensitive skin as glycerin and sorbitol provide excellent hydration, while tocopheryl acetate offers antioxidant protection. Tropaeolum majus stem extract and hydrolyzed candida saitoana extract offer general skincare benefits that support hydration but are not specialized for your dry or flaky skin concerns.
  • The formula is safe for your dry and sensitive skin, containing no harsh or irritating ingredients.
  • It provides good moisturizing benefits, making it a generally suitable option for maintaining skin hydration.

How to apply

  • Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
  • Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
  • Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
  • Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
  • Do a patch test before your first use. Avoid the eye area to prevent any irritation.

Questions and answers

How well does GlyMed Plus Oxygen Cream work for dry sensitive skin?

GlyMed Plus Oxygen Cream works reasonably well for dry sensitive skin, providing moderate hydration and antioxidant protection without harsh ingredients. A moisturizer for this skin type needs deep-nourishing ingredients and soothing agents that directly target flakiness and support the skin barrier.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this cream a good fit for dry sensitive skin?

Glycerin and sorbitol make this cream a good fit for dry sensitive skin by providing very good hydration and helping maintain moisture. To fit this skin type best, a product of this type needs highly effective soothing ingredients, deep nourishment, and strong support for the skin barrier.

Clinical, Cosmetic and Investigational Dermatology, 2017

What does Hydrolyzed Candida Saitoana Extract do for dry sensitive skin?

Hydrolyzed Candida Saitoana Extract helps smooth and soften dry sensitive skin by supporting its natural renewal process. This ingredient is unlikely to cause irritation, making it gentle enough for daily use.

What does Lactobacillus Wasabia Extract do for dry sensitive skin?

Lactobacillus Wasabia Extract helps hydrate dry sensitive skin by supporting the skin barrier and soothing irritation. This ingredient is unlikely to cause discomfort and may improve overall skin comfort.

Where does this cream go in a skincare routine for dry sensitive skin?

Apply this moisturizing treatment in the evening as part of your routine for dry sensitive skin. A consistent skincare regimen that includes a moisturizer helps improve hydration and visual dryness in dry skin.

The Journal of Dermatological Treatment, 2022Clinical, Cosmetic and Investigational Dermatology, 2017

Can I use it with retinol, and in what order?

You can use this treatment with retinol by applying the retinol first, letting it absorb, and then following with this cream to help keep your dry skin soft and comfortable. This product is unlikely to irritate your skin, though dry and flaky skin generally needs barrier-restoring ingredients like ceramides and rich oils for better support.

Cutis, 2006

How often should I use this cream?

You can use this moisturizing treatment in your evening routine as part of maintaining daily skin hydration. Daily application helps improve skin moisture and keeps dry skin soft and comfortable.

Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021

Can it clog pores, cause breakouts or purging for dry sensitive skin?

This cream is unlikely to clog pores or cause breakouts for dry sensitive skin because its formula is safe and contains no harsh or irritating ingredients.

Can I use this cream around the eyes or on my body?

You can use this cream on the thin skin around your eyes and on your body because its safe formula is gentle. However, to properly care for dry and sensitive skin, a product of this type needs rich moisturizing ingredients and soothing barrier-repair agents.

Surgical and Radiologic Anatomy, 2002

Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017

  • Exogenous sorbitol protected epidermal keratinocytes from osmotic toxicity in vitro and significantly improved skin barrier repair and moisturization in individuals in arid environments.

    Journal of Cosmetic Science, 2013

  • Vitamin E in O/W and W/O emulsions significantly increased stratum corneum hydration and enhanced water-binding capacity, with an optimum concentration of 5%.

    Arzneimittel-Forschung, 1998

  • Isosaponarin isolated from wasabi leaf increased type I collagen production in human fibroblasts by up-regulating TbetaR-II and P4H expression.

    Journal of Natural Medicines, 2010

  • Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

    Experimental Dermatology, 2003

  • Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

    Journal of Periodontology, 2009

  • Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

    Journal of Cosmetic Dermatology, 2022

  • The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

    Journal of Cosmetic Dermatology, 2020

  • Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

    International Journal of Cosmetic Science, 2001

  • Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

    Journal of Drugs in Dermatology, 2012

  • Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.

    Journal of Cosmetic Dermatology, 2025

  • Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.

    Contemporary Clinical Trials Communications, 2021

  • Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.

    Journal of Cosmetic Dermatology, 2024

Why other moisturizers fit dry sensitive skin better

  • Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

    Indian Journal of Pharmaceutical Sciences, 2016

  • Nanoemulsions containing Macadamia integrifolia seed oil successfully enhanced skin hydration and reduced wrinkles in human volunteers, outperforming conventional emulsions in skin hydration enhancement.

    Nanomaterials, 2024

Ingredients

Water, Isodecyl Neopentanoate, Isononyl Isononanoate, Glycerin, Tropaeolum Majus Stem Extract, Polyacrylate Crosspolymer-6, Hydroxystearyl Glucoside, Hydrolyzed Candida Saitoana Extract, Sorbitol, Lactobacillus Wasabia Extract, Sake Extract, Tocopheryl Acetate, Tetrahexyldecyl Ascorbate, Hydroxystearyl Alcohol, Grapefruit Peel Oil, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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