EltaMD UV Sport Broad-Spectrum SPF 50 for mature skin

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Questions and answers

What the research says

• Co-encapsulation of alpha-tocopherol and alpha-tocopheryl acetate in nanostructured lipid carrier gel formulations significantly enhanced moisture retention up to 68% and improved skin elasticity in human volunteers compared to a solution gel.

  Scientific Reports, 2025

• Vitamin E in O/W and W/O emulsions significantly increased stratum corneum hydration and enhanced water-binding capacity, with an optimum concentration of 5%.

  Arzneimittel-Forschung, 1998

• Liposomal encapsulation of octyl methoxycinnamate increases its safety, skin affinity, and in vivo solar photoprotection factor while slowing its release and enhancing retention in the stratum corneum compared to a conventional formulation.

  International Journal of Nanomedicine, 2013

• Multilamellar liposomes containing octyl methoxycinnamate increased stratum corneum accumulation and reduced deeper skin penetration compared to conventional emulsions and small unilamellar liposomes in six volunteers, resulting in a slightly better sun protection factor.

  Journal of Cosmetic Science, 2008

• Chemical sunscreens containing avobenzone, octocrylene, homosalate, and octisalate showed no to minimal risks of dermal irritation, sensitization, photo-allergy, and photo-irritation in human subjects.

  Journal of Drugs in Dermatology, 2025

• Topical 0.5% hyaluronic-ZnO nanogel applied twice daily reduced inflammatory-lesion counts by 58% at week four in human subjects compared to baseline without causing erythema.

  Biomedicines, 2025

• Nels cream achieved a similar reduction in inflammatory and noninflammatory lesion counts compared to 5% benzoyl peroxide in acne vulgaris patients, but caused significantly fewer side-effects such as peeling and dryness.

  Clinical and Experimental Dermatology, 2000

• Topically applied coated and uncoated zinc oxide nanoparticles under flexing and massage are retained in the stratum corneum with no significant penetration into the viable epidermis and no cellular toxicity in human skin.

  Nanomedicine, 2016

• Replacing 20% of the chemical UV filter octyl methoxycinnamate with urucum oil in solid lipid nanoparticles maintained the skin protection factor without inducing toxic responses or significant skin penetration in human volunteers.

  Skin Pharmacology and Physiology, 2018

• Encapsulation of ethylhexyl methoxycinnamate and butyl methoxydibenzoylmethane in lipid microparticles significantly reduced their in vivo human skin penetration compared to nonencapsulated filters.

  Skin Pharmacology and Physiology, 2011

• The application of a sunscreen formulation containing ethylhexyl methoxycinnamate, ethylhexyl salicylate, methyl anthranilate, and octocrylene does not significantly affect critical acne-related species such as Cutibacterium acnes and Staphylococcus epidermidis, refuting the induction of facial dysbiosis in men.

  Archives of Dermatological Research, 2024

• Simulated real-life dermal sunscreen exposure in twenty human volunteers leads to the systemic bioavailability and urinary excretion of the UV filter 2-ethylhexyl salicylate and its metabolite, reaching concentration peaks at 7 to 8 hours with 70-80% of overall excretion within 24 hours.

  Archives of Toxicology, 2019

• Controlled single dermal exposure to an EHS-containing sunscreen in three volunteers resulted in delayed systemic resorption with elimination half-lives between 6.6 and 9.7 hours, where the parent compound EHS occurred as the dominant urinary parameter.

  Archives of Toxicology, 2024

• Dermal exposure to EHS-containing sunscreen leads to the urinary excretion of EHS as the main biomarker alongside major metabolites 5OH-EHS, 5cx-EPS, 4OH-EHS, and 5oxo-EHS, measured using an extended enzymatic hydrolysis and on-line SPE LC-MS/MS method.

  Talanta, 2024

• Topical application of a honey, olive oil, and beeswax mixture three times daily for up to 4 weeks resulted in clinical responses in 86% of patients with pityriasis versicolor, 78% with tinea cruris, and 75% with tinea corporis.

  Complementary Therapies in Medicine, 2004

• A prototype body cream containing bee venom, propolis, honey, beeswax, and royal jelly demonstrated stability for 90 days, high antioxidant capacity of 85.45%, lack of cytotoxicity with over 70% cell viability, and no irritation or allergic reaction in dermatological analysis, while improving skin parameters in a panel test.

  Journal of Cosmetic Dermatology, 2022

• MUD1 protected human dermal fibroblasts against AAPH-induced oxidative stress by increasing cell viability, reducing oxidative damage, improving mitochondrial functionality, and enhancing wound healing capacities.

  International Journal of Molecular Sciences, 2018

• Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.

  Journal of Cosmetic Dermatology, 2025

• Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.

  Contemporary Clinical Trials Communications, 2021

• Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.

  Journal of Cosmetic Dermatology, 2024

Ingredients

Zinc Oxide, Octinoxate, Octisalate, Bees Wax, Butylene Glycol, Cetyl Dimethicone, Cetyl Peg Ppg-10 1 Dimethicone, Disodium Edta, Hexyl Laurate, Hydrogenated Castor Oil, Iodopropynyl Butylcarbamate, Isopropyl Palmitate, Octyldodecyl Neopentanoate, Polyglyceryl-4 Isostearate, Water, Sodium Chloride, Tocopheryl Acetate, Triethoxycaprylylsilane

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.