Cure Natural Aqua Gel for mature skin

How to apply

Questions and answers

What the research says

• Topical application of a 2% cream containing combined fruit extracts for 56 days significantly reduced wrinkle depth by 11.5%, length by 10.07%, and area by 29.55% in 21 female subjects compared to a placebo.

  Clinical, Cosmetic and Investigational Dermatology, 2015

• Topical application of Ginkgo biloba cream for two weeks reduced wrinkles and improved skin shape, texture, and tautness in human volunteers compared to baseline.

  Drug Development and Industrial Pharmacy, 2023

• Incorporating rosmarinic acid into sunscreens enhanced the in vivo SPF of octocrylene by over 157% and reduced lipid peroxidation in the human stratum corneum.

  Antioxidants, 2025

• A hydrogen water mask pack increased skin density by 18.41% compared to 9.93% for a commercial sample in participants after 4 weeks.

  International Journal of Molecular Sciences, 2020

• Topical application of magnetized saline water serum improved skin hydration, reduced transepidermal water loss, sebum content, melanin index, and erythema index, and activated autophagy by increasing Beclin-1 and decreasing mTOR in females wanting to enhance facial and neck skin appearance.

  Cureus, 2023

• Reconstruction of human skin equivalents under reduced relative humidity of 40% increased pyrrolidone carboxylic acid levels to match native tissue, but stratum corneum hydration levels remained lower unless water was topically applied.

  The Journal of Investigative Dermatology, 2008

• A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.

  Clinical Pharmacology, 2018

• Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief.

  Plastic and Reconstructive Surgery, 2018

• Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo.

  Journal of Alternative and Complementary Medicine, 2010

• A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris.

  Clinical, Cosmetic and Investigational Dermatology, 2015

• A cosmetic formulation combining green tea and Ginkgo biloba extracts synergistically improved skin elasticity and skin barrier function in 48 volunteers compared to individual extracts.

  Journal of Drugs in Dermatology, 2014

• Laricitrin 3-rutinoside isolated from Ginkgo biloba fruits inhibited TNF-alpha-stimulated ROS generation, suppressed MMP-1 secretion, protected against collagen degradation, and diminished pro-inflammatory cytokines IL-6 and IL-8 in normal human dermal fibroblasts.

  Antioxidants, 2023

• Topical application of rosemary essential oil-loaded lipid nanoparticles in gel vehicles significantly increased skin hydration compared to gels containing free oil, and increased elasticity to a lesser extent, in ten healthy volunteers.

  Pharmaceutics, 2017

• Topical application of a cream containing the NHE1 activator rosmarinic acid decreased skin surface pH and transepidermal water loss while increasing skin hydration in 50-60-year-old adult females compared to vehicle cream and no treatment.

  International Journal of Molecular Sciences, 2022

• An alcoholic extract of rosemary leaves, Rosm1, demonstrates strong antioxidant activity and inhibits oxidative alterations to skin surface lipids when evaluated in vitro and in vivo.

  International Journal of Tissue Reactions, 2000

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

Ingredients

Water, Glycerin, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Dicocodimonium Chloride, Steartrimonium Bromide, Aloe Barbadensis Leaf Extract, Ginkgo Biloba Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Butylene Glycol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.