ALODERMA 99% Organic Aloe Vera Gel for combination skin

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Questions and answers

What the research says

• A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.

  Clinical Pharmacology, 2018

• A preservative system containing 1,2-hexanediol and caprylyl glycol showed no delayed Type IV dermal sensitivity reactions in 200 subjects when tested as a 15% mixture in carbomer gel and in a cosmetic formulation.

  Cutaneous and Ocular Toxicology, 2009

• Sensory skin irritation potential of 1,2-alkanediols increased with alkane chain length, whereas 1,2-hexanediol showed the lowest objective skin irritation potential compared to both shorter and longer chain lengths, and percutaneous absorption negatively correlated with alkane chain length.

  International Journal of Cosmetic Science, 2011

• Pranoprofen-loaded nanostructured lipid carriers dispersed in Carbomer 940 and Sepigel 305 gels provided sustained drug release and demonstrated anti-inflammatory efficacy in animal models without causing skin irritation or altering biophysical properties in humans.

  Gels, 2023

• Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief.

  Plastic and Reconstructive Surgery, 2018

• Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo.

  Journal of Alternative and Complementary Medicine, 2010

• Formulations containing 0.10%, 0.25%, and 0.50% freeze-dried Aloe vera extract increased stratum corneum water content compared with the vehicle in 20 female subjects, while transepidermal water loss was not modified.

  Skin Research and Technology, 2006

• Topical chloramphenicol-betamethasone combined with sodium hyaluronate/trehalose/carbomer gel compared to chloramphenicol-betamethasone alone reduced most subjective symptoms at 1 week but increased blurred vision at 4 weeks following strabismus surgery in 31 patients, with no significant differences in conjunctival inflammation between treatments.

  Journal of Ocular Pharmacology and Therapeutics, 2019

• Incorporating nanoemulsions into hydrogels with increasing Carbopol 934 proportions from 1% to 3% progressively decreased the percutaneous flux rates of terbinafine and citral, increased drug accumulation in the stratum corneum while decreasing it in the epidermis/dermis compared to nanoemulsions alone, and shifted delivery routes from skin appendages to intercellular paths.

  International Journal of Nanomedicine, 2016

• Topical liquiritin carbomer gel treatment restored skin barrier function, increased barrier proteins and antioxidant enzymes, and decreased inflammatory cytokines and oxidative stress in a mouse model of glucocorticoid-induced skin inflammation.

  Pharmaceutics, 2024

• A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects.

  Journal of Ginseng Research, 2022

• Topical 2% tea lotion significantly decreased inflammatory lesions and was superior to 5% zinc sulphate solution in patients with acne vulgaris.

  Saudi Medical Journal, 2008

• Topical 2% tea lotion significantly reduced the mean lesion count of papules and pustules in patients with mild to moderate acne vulgaris compared to a control solution over 2 months.

  Saudi Medical Journal, 2006

Ingredients

Aloe Barbadensis Leaf Juice, Carbomer, 1,2-Hexanediol, Hydroxyacetophenone, Triethanolamine, Disodium Edta

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.