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Advanced Clinicals HYALURONIC SERUM for dry sensitive skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Advanced Clinicals HYALURONIC SERUM

Average

  • HighDry Skin Fit
  • HighEffectiveness
  • HighSafety

Works for dry sensitive skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate hydration for your dry or flaky skin, as glycerin and hyaluronic acid provide humectant action while chondrus crispus extract and aloe barbadensis leaf juice offer emollient benefits.
  • This formula is highly suitable for dry skin due to its humectant and emollient ingredients, though it does not offer targeted treatment for flakiness.
  • The safety profile is excellent, with no risks of irritation for your dry and sensitive skin due to the absence of prohibited or harsh ingredients.

How to apply

  • Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
  • Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
  • Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
  • Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
  • Do a patch test before your first use. Avoid the eye area to prevent any irritation.

People Say

★4.8Overall rating based on 800+ reviews

This serum is highly effective for providing instant and deep hydration, improving skin texture, and reducing the appearance of fine lines, making it a popular choice for dry, dehydrated, and aging skin types. Users frequently experience a plumper complexion and diminished fine lines. Some users note a slightly sticky finish or a strong fragrance.

Highlights

  • Deeply hydrating Mostly Mentioned
    • “instant hydration for dry skin”
    • “keeps my skin feeling hydrated”
    • “It moisturizes. It is used daily.”
    • “It became less dehydrated”
  • Great value Often Mentioned
    • “EXCELLENT PRODUCT FOR PRICE”
    • “Great product at a great price”
    • “superb price”
    • “more reasonably priced than other products”
  • Reduces fine lines Often Mentioned
    • “reducing the appearance of my laugh lines”
    • “fine lines are less noticeable”
    • “visibly plumps skin”
    • “smooths fine lines”
  • Absorbs quickly Sometimes Noted
    • “absorbs well”
    • “gets soaked up completely”
    • “still absorbs quickly!”
    • “absorbs quickly without any greasy residue”
  • Noticeable fragrance Sometimes Noted
    • “the limonene is pretty strong”
    • “switch to something with less fragrance”
    • “The scent is a bit like vitamin B complex.”
    • “strong scent”
  • Slightly sticky finish Sometimes Noted
    • “It's a little sticky but It absorbs well.”
    • “sticky. It provides good hydration”
    • “sticky”
  • Potential ingredient concerns Rarely Noted
    • “if I used this when my barrier didn't exist it probably would have irritated me”
    • “I am surprised that it didn't break me out that time”
    • “I don't know what happened to my skin after I learn to analyze the ingredients”

Sources: lovi.care, walmart.com, ebay.com, iherb.com, skinsort.com, desertcart.ae, and more

Questions and answers

How well does Advanced Clinicals Hyaluronic Serum work for dry sensitive skin?

This serum works reasonably well for your dry sensitive skin, offering moderate hydration and a safe formula without harsh ingredients. To fit this skin type best, a product of this type needs multiple forms of hyaluronic acid, pro vitamin B5, and ceramides for deep moisture and barrier support.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this serum a good fit for dry sensitive skin?

Hyaluronic acid and glycerin help make this serum a good fit by pulling moisture into dry skin, while aloe leaf juice helps calm it. To fit this skin type even better, a moisturizing treatment needs multiple forms of hyaluronic acid, pro vitamin B5, and ceramides for deep hydration and barrier support.

Clinical, Cosmetic and Investigational Dermatology, 2017

What does Hyaluronic Acid do for dry sensitive skin?

Hyaluronic acid is a great fit for dry, sensitive skin because it brings a large boost in hydration, making the skin feel soft and smooth while improving barrier function. It helps calm tightness and dryness, and is unlikely to cause irritation.

Journal of Drugs in Dermatology, 2011Dermatology and Therapy, 2021

What does Glycerin do for dry sensitive skin?

Glycerin helps dry sensitive skin by drawing moisture into the skin and keeping it there, making the skin soft and smooth. It is very gentle and unlikely to cause irritation while improving how well the skin holds onto water. This type of skin needs ingredients that boost hydration and repair the barrier without causing stinging.

Clinical, Cosmetic and Investigational Dermatology, 2017The British Journal of Dermatology, 2008

Where does this serum go in a skincare routine for dry sensitive skin?

This serum goes in the evening routine, placed after your cleanser and toner and before your moisturizer. Putting it in the evening keeps things simple and avoids extra safety concerns around sun exposure.

Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum before your retinol product to help keep your dry sensitive skin comfortable. This type of product needs rich moisturizing ingredients like ceramides and nourishing oils to fully support and protect sensitive skin.

How often should I use this serum?

Use this serum in your evening routine for simplicity and extra safety around sun exposure. If your dry sensitive skin tolerates it well and you see good results, you may carefully use it more often.

Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores or cause irritation for your dry sensitive skin due to the absence of harsh ingredients. To care for skin like this, a product needs gentle soothing ingredients and rich moisturizers to keep the skin calm and comfortable.

Can I use this serum around the eyes or on my body?

You can use this serum on the thin skin around your eyes and on your body because its safety profile is excellent and it is unlikely to cause irritation. However, a product for dry sensitive skin needs stronger ingredients like targeted moisturizers and rich emollients to better handle flakiness.

Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (limonene, geraniol, hexyl cinnamal, and linalool).

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017

  • κ-carrageenan tetrasaccharide treatment protects against particulate matter-induced oxidative stress, inflammation, and skin barrier dysfunction in human HaCaT keratinocytes by chelating metal ions and modulating STAT3, PI3K/AKT, and PPAR-γ pathways.

    International Journal of Biological Macromolecules, 2025

  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011

  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022

  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019

  • The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

    Journal of Cosmetic Dermatology, 2020

  • Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

    International Journal of Cosmetic Science, 2001

  • Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

    Journal of Drugs in Dermatology, 2012

  • A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.

    Clinical Pharmacology, 2018

  • Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief.

    Plastic and Reconstructive Surgery, 2018

  • Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo.

    Journal of Alternative and Complementary Medicine, 2010

Why other moisturizers fit dry sensitive skin better

  • Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.

    Arzneimittel-Forschung, 2000

  • A cream containing panthenol, prebiotics, and probiotic lysate improved facial sensitive skin symptoms and skin barrier function in 110 participants over 28 days.

    Skin Research and Technology, 2024

  • A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.

    Journal of Cosmetic Dermatology, 2024

Ingredients

Water, Ethoxydiglycol, Glycerin, Pyrus Malus Fruit Extract, Peg-12 Dimethicone, Hyaluronic Acid, Chondrus Crispus Extract, Camellia Sinensis Leaf Extract, Aloe Barbadensis Leaf Juice, Sodium Carboxymethyl Beta-Glucan, Epilobium Angustifolium Stem Extract Flower Leaf, Tocopheryl Acetate, Xanthan Gum, Phenoxyethanol, Maltodextrin, Tetrasodium Glutamate Diacetate, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Citric Acid, Limonene, Geraniol, Hexyl Cinnamal, Linalool

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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QR code: get the Lovi app
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