Lipohydroxy acid

Lipohydroxy acid gently smooths skin texture, softens fine lines, reduces dark spots, balances oil, and clears blemishes while encouraging gentle renewal. It suits dry skin and oily skin particularly well, and is most commonly found in exfoliators and toners. When applying it, simply keep it apart from niacinamide to support a balanced daily routine.
Journal of Cosmetic Dermatology, 2021Journal of Cosmetic Dermatology, 2008Cutis, 2012
This page shows lipohydroxy acid products with a Lovi page. For every product, and a routine built for your skin, use the Lovi app.
Popular lipohydroxy acid products
- La Roche-Posay Effaclar Medicated Gel Cleanser
- SkinCeuticals LHA Cleanser Gel
-
SkinCeuticals
Blemish + Age Defense
SAR 458.33
- L'Oreal Paris Age Perfect Cell Renewal Midnight Cream
-
La Roche-Posay
Effaclar Mat
SAR 44.89
- La Roche-Posay Effaclar Clarifying Solution
-
La Roche-Posay
Effaclar Ultra Concentrated Serum
SAR 142.00
-
MEDIHEAL
Phyto-Enzyme Peeling Pad
SAR 118.00
Lipohydroxy acid exfoliators
- La Roche-Posay Effaclar Clarifying Solution
-
La Roche-Posay
Effaclar Ultra Concentrated Serum
SAR 142.00
-
MEDIHEAL
Phyto-Enzyme Peeling Pad
SAR 118.00
-
StriVectin
Daily Reveal Exfoliating Pads
SAR 241.56
-
Anua
Heartleaf LHA Moisture Peeling Gel
SAR 24.35
- La Roche-Posay Effaclar Micro-Peeling Purifying Gel
What reviewers say about popular lipohydroxy acid products
The highlight reviewers mention most for each popular lipohydroxy acid product on Lovi.
La Roche-Posay Effaclar Medicated Gel Cleanser Controls oil ★4.6 · 2.3k+ reviews
SkinCeuticals LHA Cleanser Gel Deeply exfoliates ★4.6 · 800+ reviews
SkinCeuticals Blemish + Age Defense Clears stubborn acne ★4.6 · 1.9k+ reviews
- Improves skin texture
- Reduces excess oil
- “cystic acne shrinking”
L'Oreal Paris Age Perfect Cell Renewal Midnight Cream Deep hydration ★4.6 · 6.6k+ reviews
- Luxurious texture
- Visible radiance
- “wake up with soft skin”
What people say about Age Perfect Cell Renewal Midnight Cream
La Roche-Posay Effaclar Mat Effective Oil Control ★4.4 · 1.4k+ reviews
La Roche-Posay Effaclar Clarifying Solution Minimizes pores ★4.5 · 2.2k+ reviews
- Gentle and non-drying
- Smoothes texture
- “effective at unclogging pores”
Lipohydroxy acid toners
- Kiehl's Daily Refining Milk-Peel Toner
-
Troubless
Clear Toner Pad
SAR 49.00
-
ma:nyo
Galactomy Clearskin Toner
SAR 140.87
- SkinCeuticals LHA Toner
-
Kiehl's
Iris Extract Activating Treatment Essence
SAR 490.00
Other lipohydroxy acid products
- La Roche-Posay Effaclar Medicated Gel Cleanser
- SkinCeuticals LHA Cleanser Gel
- Garnier Express Aclara
-
Minimalist
Salicylic Acid + LHA 2% Face Cleanser
SAR 127.09
- L'Oreal Paris Age Perfect Cell Renewal Midnight Cream
-
La Roche-Posay
Effaclar Mat
SAR 44.89
-
SkinCeuticals
Blemish + Age Defense
SAR 458.33
- La Roche-Posay Redermic R
-
Kiehl's
Vital Skin-Strengthening Super Serum
SAR 337.83
Lipohydroxy acid for dry skin
- L'Oreal Paris Age Perfect Cell Renewal Midnight Cream
- Kiehl's Daily Refining Milk-Peel Toner
-
MEDIHEAL
Phyto-Enzyme Peeling Pad
SAR 118.00
-
Kiehl's
Vital Skin-Strengthening Super Serum
SAR 337.83
-
Anua
Heartleaf LHA Moisture Peeling Gel
SAR 24.35
-
Troubless
Clear Toner Pad
SAR 49.00
-
SkinCeuticals
Blemish + Age Defense
SAR 458.33
-
StriVectin
Daily Reveal Exfoliating Pads
SAR 241.56
-
Kiehl's
Iris Extract Activating Treatment Essence
SAR 490.00
- La Roche-Posay Effaclar Medicated Gel Cleanser
- La Roche-Posay Redermic R
- SkinCeuticals LHA Cleanser Gel
Lipohydroxy acid for oily skin
-
SkinCeuticals
Blemish + Age Defense
SAR 458.33
- SkinCeuticals LHA Toner
-
Minimalist
Salicylic Acid + LHA 2% Face Cleanser
SAR 127.09
-
ma:nyo
Galactomy Clearskin Toner
SAR 140.87
-
Troubless
Clear Toner Pad
SAR 49.00
- La Roche-Posay Effaclar Clarifying Solution
- Kiehl's Daily Refining Milk-Peel Toner
- SkinCeuticals LHA Cleanser Gel
-
La Roche-Posay
Effaclar Ultra Concentrated Serum
SAR 142.00
-
MEDIHEAL
Phyto-Enzyme Peeling Pad
SAR 118.00
- La Roche-Posay Effaclar Medicated Gel Cleanser
- La Roche-Posay Redermic R
Lipohydroxy acid for combination skin
-
Minimalist
Salicylic Acid + LHA 2% Face Cleanser
SAR 127.09
-
Troubless
Clear Toner Pad
SAR 49.00
-
SkinCeuticals
Blemish + Age Defense
SAR 458.33
-
ma:nyo
Galactomy Clearskin Toner
SAR 140.87
-
Kiehl's
Iris Extract Activating Treatment Essence
SAR 490.00
- La Roche-Posay Effaclar Medicated Gel Cleanser
- SkinCeuticals LHA Toner
-
La Roche-Posay
Effaclar Ultra Concentrated Serum
SAR 142.00
-
MEDIHEAL
Phyto-Enzyme Peeling Pad
SAR 118.00
- Kiehl's Daily Refining Milk-Peel Toner
-
Anua
Heartleaf LHA Moisture Peeling Gel
SAR 24.35
- La Roche-Posay Redermic R
Lipohydroxy acid for sensitive skin
- Kiehl's Daily Refining Milk-Peel Toner
-
Kiehl's
Iris Extract Activating Treatment Essence
SAR 490.00
-
Anua
Heartleaf LHA Moisture Peeling Gel
SAR 24.35
-
La Roche-Posay
Effaclar Ultra Concentrated Serum
SAR 142.00
-
Troubless
Clear Toner Pad
SAR 49.00
-
MEDIHEAL
Phyto-Enzyme Peeling Pad
SAR 118.00
- L'Oreal Paris Age Perfect Cell Renewal Midnight Cream
-
Kiehl's
Vital Skin-Strengthening Super Serum
SAR 337.83
-
SkinCeuticals
Blemish + Age Defense
SAR 458.33
-
ma:nyo
Galactomy Clearskin Toner
SAR 140.87
- La Roche-Posay Redermic R
- SkinCeuticals LHA Cleanser Gel
What to combine lipohydroxy acid with
| Ingredient | Together | How to use them |
|---|---|---|
| Keep apart | Use them at different times of day, applying the hydroxy acid first and niacinamide later, because combining them causes irritation. Lipohydroxy acid and niacinamide |
From the ingredient rules behind the "Works well with" and "Don't mix with" notes on every product in the Lovi app.
Questions and answers
What does lipohydroxy acid do for the skin?
Lipohydroxy acid helps reduce acne severity, post-inflammatory dark spots, and oiliness, and may improve the look of fine lines, wrinkles, and skin texture. It also helps smooth and thicken the outer skin layer for a more even appearance.
Journal of Cosmetic Dermatology, 2021Journal of Cosmetic Dermatology, 2008
How do you use lipohydroxy acid?
You use lipohydroxy acid daily, or as directed by your product, but you should keep it apart from niacinamide by using them at different times of day with the hydroxy acid applied first to avoid irritation. It may help reduce acne, fine lines, and hyperpigmentation when used as part of your routine.
Journal of Cosmetic Dermatology, 2021Journal of Cosmetic Dermatology, 2008
Should you use lipohydroxy acid in the morning or at night?
You can use lipohydroxy acid in your routine, but you should keep it apart from niacinamide by using them at different times of day and applying the hydroxy acid first. This helps prevent irritation.
Can you use lipohydroxy acid every day?
Yes, you can use lipohydroxy acid daily, as daily treatment with products containing it helps control oily skin and reduce acne lesions. It is unlikely to cause adverse reactions when used as directed in facial serums and masks.
Journal of Cosmetic Dermatology, 2021Journal of Cosmetic Dermatology, 2023
Does lipohydroxy acid cause purging or irritation?
Lipohydroxy acid may cause irritation when combined with niacinamide, so keep them apart by using them at different times of day and applying the hydroxy acid first. Lovi assigns this a fit rating based on compatibility rules.
Which skin types is lipohydroxy acid best for?
Lipohydroxy acid is well suited for various skin types, with top-rated options including SkinCeuticals Blemish + Age Defense for oily skin and ma:nyo Galactomy Clearskin Toner for acne-prone skin. Lovi rates SkinCeuticals Blemish + Age Defense as a Superior fit for oily skin.
Can you use lipohydroxy acid with niacinamide?
You should keep lipohydroxy acid and niacinamide apart and use them at different times of day, applying the hydroxy acid first and niacinamide later, because combining them causes irritation.
Research on lipohydroxy acid
Behind this ingredient guide
Lovi checks every ingredient with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-

Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.
































































