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Sesderma vs SKIN&CO

Rated by Lovi 路 Unbiased, science-based skincare AI trained on real user outcomes 路 How the Fit score works

Sesderma and SKIN&CO are respected skincare brands offering expertly crafted formulas. Sesderma is beloved for its advanced serums and botanical extracts, suiting sensitive, hyperpigmented, and aging skin best, whereas SKIN&CO is loved for its deeply nourishing moisturizers, suiting dry, normal, and combination skin best. The Spanish brand features standout products like the Azelac RU Serum for acne-prone skin, while the other brand delivers thoughtful care and features the Truffle Therapy Serum. Ultimately, both differ through their unique ingredient compositions and targeted approaches to refining skin texture.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Sesderma and SKIN&CO products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Sesderma vs SKIN&CO products

Questions and answers

Sesderma or SKIN&CO: which is better?

Sesderma offers a High Lovi fit for acne-prone skin and skin with dark spots with its Azelac RU Serum, while SKIN&CO provides an Average fit across all skin types with its Truffle Therapy Serum.

What is the difference between Sesderma and SKIN&CO?

Sesderma has a High fit for acne-prone skin and skin with dark spots with its Azelac RU Serum, whereas SKIN&CO offers Average fits across all skin types with its Truffle Therapy Serum. Both of the products on this page contain fragrance.

Pharmaceutics, 2021

Which is more affordable, Sesderma or SKIN&CO?

The provided page facts do not contain pricing information, so it is not possible to determine whether Sesderma or SKIN&CO is more affordable.

Which causes fewer breakouts, Sesderma or SKIN&CO?

For acne-prone skin, Sesderma offers a High fit with its Azelac RU Serum, whereas SKIN&CO provides an Average fit with Truffle Therapy Serum.

Pharmaceutics, 2021

Which brand has been around longer, Sesderma or SKIN&CO?

Sesderma has been around longer, having been founded in Spain in 1989, whereas SKIN&CO was founded in 2008.

Do Sesderma and SKIN&CO products contain fragrance?

Yes, both Sesderma and SKIN&CO include fragrance in the products on this page. Specifically, the Azelac RU Serum by Sesderma and the Truffle Therapy Serum by SKIN&CO both contain fragrance.

Which skin types are best suited for Sesderma's Azelac RU Serum compared to SKIN&CO's Truffle Therapy Serum?

Sesderma's Azelac RU Serum has a High Lovi fit for acne-prone skin, skin with dark spots, and combination skin, whereas SKIN&CO's Truffle Therapy Serum achieves an Average fit across all listed skin types. Both products on this page contain fragrance.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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