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Medik8 vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Medik8 and Sesderma are accomplished skincare brands that offer serums, moisturizers, eye products, toners, and advanced formulas. The British brand founded in 2009 features hyaluronic acid to lengthen the toxin wrinkle effect duration, suiting dry skin and dry sensitive skin best with highlights like Surface Radiance Cleanse, Oxy-R Peptides, and Total Moisture Daily Facial Cream. Meanwhile, the Spanish brand founded in 1989 utilizes botanical extracts and active compounds to suit sensitive, hyperpigmented, and aging skin types, featuring standout options such as the Azelac RU Serum. Ultimately, both differ through their distinct heritage, proprietary ingredients, and tailored solutions for specific dermatological concerns.

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

loreal.commedik8.comtracxn.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Medik8 and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Medik8 vs Sesderma products

Medik8 vs Sesderma serums and treatments

Questions and answers

Medik8 or Sesderma: which is better?

Medik8 is the better choice for most shoppers on this page, as it offers a wide range of gentle serums and moisturizers that feature hyaluronic acid and help with deep hydration. Hyaluronic acid helps improve skin quality and signs of aging.

Dermatologic Therapy, 2022

What is the difference between Medik8 and Sesderma?

Medik8 offers a wide range of serums, creams, and cleansers that focus heavily on hydration and anti-aging with key ingredients like hyaluronic acid, whereas Sesderma is represented on this page by just a single serum, Azelac RU Serum, which contains fragrance.

Drug Delivery, 2017Dermatologic Therapy, 2022

Which is more affordable, Medik8 or Sesderma?

Reviewers of Medik8 note its high price point, while affordability details for Sesderma are not mentioned on this page.

Which causes fewer breakouts, Medik8 or Sesderma?

Medik8 features a wide range of products on this page with high or superior fits for acne-prone skin, whereas Sesderma includes only Azelac RU Serum which has a high fit for acne-prone skin.

Which brand has been established longer, Medik8 or Sesderma?

Sesderma has been established longer, having been founded in Spain in 1989, whereas Medik8 was founded in the United Kingdom in 2009.

Do any Medik8 products contain fragrance, and how does that compare to Sesderma?

Yes, Total Moisture Daily Facial Cream is the only Medik8 product on this page with fragrance, whereas the single Sesderma product listed also contains fragrance.

Which brand offers more products for dry skin according to the page?

Medik8 offers more products for dry skin on this page, including options that achieve a Superior Lovi fit level like Bakuchiol Peptides and Press & Glow, whereas Sesderma lists only Azelac RU Serum which has a Low fit for dry skin.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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