Allies of Skin vs Sesderma
Allies of Skin and Sesderma are distinguished skincare lines known for advanced serums, luxurious moisturizers, and meticulously engineered formulas powered by ingredients like niacinamide and botanical extracts. The former suits acne-prone and oily acne-prone skin best through barrier-respecting treatments, while the latter caters thoughtfully to sensitive, hyperpigmented, and aging skin types. Both brands differ in their regional roots and specific targeted approaches, offering standout solutions like the Molecular Saviour Probiotics Treatment Mist, the Peptides & Antioxidants Firming Daily Treatment, and the Azelac RU Serum. Through such specialized care, each brand works synergistically to refine skin texture, address dark spots, and promote a radiant complexion.
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Allies of Skin and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Allies of Skin vs Sesderma products
Questions and answers
Allies of Skin or Sesderma: which is better?
Allies of Skin offers a much wider range of fragrance-free products on this page and tends to fit acne-prone, oily acne-prone, and dry skin better. Niacinamide helps reduce pigmentation and suppress melanosome transfer, a benefit found across Allies of Skin products.
The British Journal of Dermatology, 2002Journal of Cosmetic Dermatology, 2004
What is the difference between Allies of Skin and Sesderma?
Allies of Skin offers a wider range of fragrance-free products that Lovi rates as a High to Superior fit for several skin types, whereas Sesderma features just one serum on this page that contains fragrance. Niacinamide helps reduce pigmentation.
The British Journal of Dermatology, 2002Journal of Cosmetic Dermatology, 2004
Which is more affordable, Allies of Skin or Sesderma?
Reviewers note that Allies of Skin has a high price point, while pricing details for Sesderma are not mentioned on this page.
Which causes fewer breakouts, Allies of Skin or Sesderma?
Allies of Skin fits acne-prone skin with High or Superior Lovi levels across multiple products on this page and includes Niacinamide, which helps reduce skin irritation and blemishes. Sesderma offers the Azelac RU Serum, which has a High fit for acne-prone skin.
The British Journal of Dermatology, 2002Journal of Cosmetic Dermatology, 2004
Which brand has more products that contain no fragrance?
Allies of Skin has more products that contain no fragrance, as every product on this page from the brand lists no fragrance in its ingredients. In contrast, the Azelac RU Serum from Sesderma contains fragrance.
Which brand was founded earlier and in which country?
Sesderma was founded earlier in 1989 in Spain, whereas Allies of Skin was founded in 2016.
What are some common complaints reviewers have about Allies of Skin?
Reviewers often complain about a high price point and initial irritation or skin reactions with Allies of Skin. Some shoppers also note packaging and mechanical issues.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Clinical efficacy of facial masks containing yoghurt and Opuntia humifusa Raf. (F-YOP)
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Effects of a Greek Yoghurt-based Complex on the Human Facial Skin Microbiome
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.







