Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
Benzyl alcohol · International Journal of Toxicology, 2001Formation and stability of oil-in-water nanoemulsions containing rice bran oil: in vitro and in vivo assessments
Rice bran oil · Journal of Nanobiotechnology, 2011Cosmetic benefits of astaxanthin on humans subjects
Astaxanthin extract · Acta Biochimica Polonica, 2012Panax ginseng-Derived Extracellular Vesicles Facilitate Anti-Senescence Effects in Human Skin Cells: An Eco-Friendly and Sustainable Way to Use Ginseng Substances
Panax ginseng · Cells, 2021Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence
Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022Topical use of dexpanthenol in skin disorders
Panthenol, Vitamin b5 · American Journal of Clinical Dermatology, 2002The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review
Aloe barbadensis leaf juice · Iranian Journal of Medical Sciences, 2019Cutaneous photoprotection from ultraviolet injury by green tea polyphenols
Camellia sinensis extract · Journal of the American Academy of Dermatology, 2001Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes
Camellia sinensis, Epigallocatechin gallate · The Journal of Investigative Dermatology, 2013Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: a possible role in acne vulgaris
Squalane · The Journal of Investigative Dermatology, 2006Regulatory effects of Lactobacillus plantarum-GMNL6 on human skin health by improving skin microbiome
Lactobacillus · International Journal of Medical Sciences, 2021Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial
Tocopherol, Tocopherol vitamin e, Ascorbic acid · Journal of Cosmetic Dermatology, 2020The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study
Melaleuca alternifolia tree leaf extract, Melaleuca alternifolia tree oil leaf, Melaleuca alternifolia tree extract · Indian Journal of Dermatology, Venereology and Leprology, 2007Aging skin is functionally anaerobic: importance of coenzyme Q10 for anti aging skin care
Ubiquinone · BioFactors, 2008The Effect of Lactobacillus plantarum Extracellular Vesicles from Korean Women in Their 20s on Skin Aging
Lactobacillus · Current Issues in Molecular Biology, 2022Tea tree oil reduces histamine-induced skin inflammation
Melaleuca alternifolia tree leaf extract · The British Journal of Dermatology, 2002Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin
Scutellaria baicalensis root extract · Journal of Drugs in Dermatology, 2014Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skin
Panax ginseng, Panax ginseng root extract, Panax ginseng extract · Journal of Ginseng Research, 2017Syringaresinol derived from Panax ginseng berry attenuates oxidative stress-induced skin aging via autophagy
Panax ginseng extract berry · Journal of Ginseng Research, 2022Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Chamomilla recutita flower extract matricaria flower extract, Calming chamomile extract, Chamomile · International Journal of Molecular Medicine, 2016Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract
Madecassoside, Centella asiatica extract · Indian Journal of Pharmaceutical Sciences, 2016Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling
Panax ginseng root extract, Panax ginseng extract · Journal of Ethnopharmacology, 2007Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy
Centella asiatica extract · Pharmaceutics, 2024The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction
Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects
Ubiquinone · BioFactors, 2015Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
Squalane · Scientific Reports, 2020Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations
Melaleuca alternifolia tree oil leaf, Aloe barbadensis leaf extract, Melaleuca alternifolia tree extract, Propolis extract, Aloe barbadensis leaf juice, Aloe barbadensis extract, Aloe barbadensis · Clinical Pharmacology, 2018Antioxidant properties evaluation of topical astaxanthin formulations as anti-aging products
Astaxanthin extract · Journal of Cosmetic Dermatology, 2019A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin
Camellia sinensis, Epigallocatechin gallate · The Journal of Investigative Dermatology, 2019Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin
Ceramide, Ceramides, Sphingolipids · Scientific Reports, 2022Effect of Camellia japonica oil on human type I procollagen production and skin barrier function
Camellia japonica seed oil · Journal of Ethnopharmacology, 2007Effects of Locally Applied Glycerol and Xylitol on the Hydration, Barrier Function and Morphological Parameters of the Skin
Xylitol · Acta Dermato-venereologica, 2017Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin
Ceramide np, Ceramide eop · International Journal of Dermatology, 2008The topical effect of grape seed extract 2% cream on surgery wound healing
Grape seed oil · Global Journal of Health Science, 2014Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation
Tocopherol · Journal of Cosmetic Dermatology, 2020Licochalcone A activates Nrf2 in vitro and contributes to licorice extract-induced lowered cutaneous oxidative stress in vivo
Glycyrrhiza glabra root extract licorice root extract · Experimental Dermatology, 2015Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study
Retinyl palmitate, Retinyl palmitate vitamin a · International Journal of Nanomedicine, 2021Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls
Camellia sinensis leaf extract · Experimental Dermatology, 2009Design, characterization, and clinical evaluation of argan oil nanostructured lipid carriers to improve skin hydration
Argania spinosa kernel oil, Argania spinosa kernel oil argan kernel oil · International Journal of Nanomedicine, 2014Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris
Azelaic acid · Pharmaceutics, 2021Systematic Study of Resveratrol Nanoliposomes Transdermal Delivery System for Enhancing Anti-Aging and Skin-Brightening Efficacy
Resveratrol · Molecules, 2023Role of Resveratrol in Regulating Cutaneous Functions
Resveratrol · Evidence-based Complementary and Alternative Medicine, 2020Comparison of clinical and histological effects between lactobacillus-fermented Chamaecyparis obtusa and tea tree oil for the treatment of acne: an eight-week double-blind randomized controlled split-face study
Melaleuca alternifolia tree oil leaf · Dermatology, 2014Continuous topical administration of a petrolatum formulation by a novel disposable diaper. 2. Effect on skin condition
Oil · Dermatology, 2000The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial
Madecassoside · Journal of Alternative and Complementary Medicine, 2020The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study
Madecassoside, Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy
Niacinamide · Journal of Cosmetic Dermatology, 2021Niacinamide mitigates SASP-related inflammation induced by environmental stressors in human epidermal keratinocytes and skin
Vitamin b derivatives · International Journal of Cosmetic Science, 2020Resveratrol as a factor preventing skin aging and affecting its regeneration
Resveratrol · Postepy Dermatologii I Alergologii, 2022Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy
Micellar technology · Nanoscale Research Letters, 2020Human skin penetration and local effects of topical nano zinc oxide after occlusion and barrier impairment
Calamine · European Journal of Pharmaceutics and Biopharmaceutics, 2016A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora
Panthenol, Vitamin b5 · The Journal of Dermatological Treatment, 2017Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation
Tocopheryl acetate, Tocopheryl acetate vitamin e · Urologia Internationalis, 2019Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging
Niacinamide · Scientific Reports, 2024Formulation and evaluation on human skin of a water-in-oil emulsion containing Muscat hamburg black grape seed extract
Grape seed oil · International Journal of Cosmetic Science, 2015Effect of topically applied lipids on surfactant-irritated skin
Brassica campestris seed oil, Canola oil · The British Journal of Dermatology, 1996A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population
Salicylic acid · BioMed Research International, 2020Strawberry seed extract and its major component, tiliroside, promote ceramide synthesis in the stratum corneum of human epidermal equivalents
Strawberry seed extract · PloS One, 2018A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial
Melaleuca alternifolia tree leaf extract, Melaleuca alternifolia tree extract · Archives of Dermatological Research, 2022Safflower Seed Oil and Its Active Compound Acacetin Inhibit UVB-Induced Skin Photoaging
Carthamus tinctorius seed oil · Journal of Microbiology and Biotechnology, 2020Topical beta-carotene protects against infra-red-light-induced free radicals
Beta carotene · Experimental Dermatology, 2011Structural characterization and in vivo evaluation of retinyl palmitate in non-ionic lamellar liquid crystalline system
Retinyl palmitate · Colloids and Surfaces. B, Biointerfaces, 2011Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial
Panthenol, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020Efficacy of Oxybrasion in the Treatment of Acne Vulgaris: A Preliminary Report
Sea salt · Journal of Clinical Medicine, 2022High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin
Witch hazel extract · Phytochemistry, 2001Self-Assembled Cubic Liquid Crystalline Nanoparticles for Transdermal Delivery of Paeonol
Paeonia albiflora flower extract · Medical Science Monitor, 2015A pilot randomized double-blind placebo-controlled trial on topical chamomile (Matricaria chamomilla L.) oil for severe carpal tunnel syndrome
Calming chamomile extract · Complementary Therapies in Clinical Practice, 2015Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy
Madecassoside, Centella asiatica extract, Paeonia albiflora flower extract, Centella asiatica leaf extract · Molecules, 2023Efficacy of olive leaf extract-containing cream for facial rejuvenation: A pilot study
Olea europaea leaf extract · Journal of Cosmetic Dermatology, 2020Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula
Galactomyces ferment filtrate pitera ferment filtrate, Rice ferment filtrate sake ferment filtrate · Journal of Clinical Medicine, 2021In vivo anti-ageing activity of cream containing niosomes loaded with purple glutinous rice (Oryza sativa Linn.) extract
Rice extract, Rice water, Rice · International Journal of Cosmetic Science, 2020Ammonium Glycyrrhizinate and Bergamot Essential Oil Co-Loaded Ultradeformable Nanocarriers: An Effective Natural Nanomedicine for In Vivo Anti-Inflammatory Topical Therapies
Bergamot oil · Biomedicines, 2022Inhibition of TRPV1 prevented skin irritancy induced by phenoxyethanol. A preliminary in vitro and in vivo study
Phenoxyethanol · International Journal of Cosmetic Science, 2017Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach
Calamine · Journal of Controlled Release, 2025High-Payload Nanosuspension of Centella asiatica Extract for Improved Skin Delivery with No Irritation
Asiaticoside · International Journal of Nanomedicine, 2021Effects of seaweed Laminaria japonica extracts on skin moisturizing activity in vivo
Laminaria japonica extract · Journal of Cosmetic Science, 2013Cosmetic formulations containing Lithospermum erythrorhizon root extract show moisturizing effects on human skin
Lithospermum erythrorhizon root extract · Archives of Dermatological Research, 2008Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects
Vitamin e · Journal of Cosmetic Dermatology, 2020Topical delivery of salicylates
Gaultheria procumbens leaf extract · Drug Delivery and Translational Research, 2022Night Cream Containing Melatonin, Carnosine and Helichrysum italicum Extract Helps Reduce Skin Reactivity and Signs of Photodamage: Ex Vivo and Clinical Studies
Helichrysum italicum callus extract · Dermatology and Therapy, 2020Genistein protects against ultraviolet B-induced wrinkling and photoinflammation in in vitro and in vivo models
Soybean seed extract · Genes & Nutrition, 2022Rosmarinic Acid, as an NHE1 Activator, Decreases Skin Surface pH and Improves the Skin Barrier Function
Rosemary leaf extract · International Journal of Molecular Sciences, 2022Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study
Salicylic acid · Journal of Cosmetic Dermatology, 2024Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study
Jojoba seed oil · Forschende Komplementarmedizin, 2012Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment
Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid
3-ceramide blend, Ceramide np · Skin Pharmacology and Physiology, 2022Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications
Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil
Avocado oil · Journal of Cosmetic Dermatology, 2020Preparation and evaluation of benzalkonium chloride hand sanitizer as a potential alternative for alcohol-based hand gels
Benzalkonium chloride · Saudi Pharmaceutical Journal, 2021Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris
Azelaic acid · Dermatology and Therapy, 2024Nanogel Containing Gamma-Oryzanol-Loaded Nanostructured Lipid Carriers and TiO2/MBBT: A Synergistic Nanotechnological Approach of Potent Natural Antioxidants and Nanosized UV Filters for Skin Protection
Rice bran oil, Rice extract · Pharmaceuticals, 2023A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial
Ginkgo biloba leaf extract, Mannitol · Clinical, Cosmetic and Investigational Dermatology, 2015Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial
Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs
Vitamin e · Journal of Cosmetic Dermatology, 2022Ginsenoside Re improves skin barrier function in HaCaT keratinocytes under normal growth conditions
Panax ginseng extract berry · Bioscience, Biotechnology, and Biochemistry, 2016A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide
Salicylic acid · Journal of Drugs in Dermatology, 2023Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model
Jojoba seed oil · Frontiers in Pharmacology, 2024Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study
Zinc gluconate · Clinical, Cosmetic and Investigational Dermatology, 2023Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release
Oenothera biennis oil · Biomaterials Advances, 2022Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial
Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020Safety and efficacy of Sclerocarya birrea (A.Rich.) Hochst (Marula) oil: A clinical perspective
Sclerocarya birrea seed oil, Sclerocarya birrea oil · Journal of Ethnopharmacology, 2015Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function
Propanediol · International Journal of Cosmetic Science, 2024A Rose Extract Protects the Skin against Stress Mediators: A Potential Role of Olfactory Receptors
Rosa centifolia flower extract · Molecules, 2020Efficacy and tolerability of the investigational topical cream SD-101 (6% allantoin) in patients with epidermolysis bullosa: a phase 3, randomized, double-blind, vehicle-controlled trial (ESSENCE study)
Allantoin · Orphanet Journal of Rare Diseases, 2020Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial
Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris
Citric acid · Journal of Cosmetic Dermatology, 2021Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract
Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane
Cyclopentasiloxane · International Journal of Toxicology, 2011Whitening effect of alpha-bisabolol in Asian women subjects
Bisabolol, Chamomilla recutita oil flower matricaria oil flower · International Journal of Cosmetic Science, 2010The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study
Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023Is benzyl alcohol a significant contact sensitizer?
Benzyl alcohol · Journal of the European Academy of Dermatology and Venereology, 2022In Vitro and Clinical Safety Assessment of the Multiple W/O/W Emulsion Based on the Active Ingredients from Rosmarinus officinalis L., Avena sativa L. and Linum usitatissimum L
Rosemary leaf extract · Pharmaceutics, 2021Expanding the anti-inflammatory potential of Moringa oleifera: topical effect of seed oil on skin inflammation and hyperproliferation
Moringa seed oil, Moringa oleifera seed oil · Journal of Ethnopharmacology, 2020Formulation strategies to modulate the topical delivery of anti-inflammatory compounds
Stearyl glycyrrhetinate · Journal of Cosmetic Science, 2013Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers
Sodium ascorbyl phosphate · Drug Research, 2017In Vitro and Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Efficacy and Safety of Nine Antiacne Medicinal Plants
Soap grass extract, Saponaria officinalis leaf extract · Evidence-based Complementary and Alternative Medicine, 2020Skin improvement and stability of Echinacea purpurea dermatological formulations
Echinacea purpurea root extract · International Journal of Cosmetic Science, 2010Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study
Beta-glucan · Journal of Cosmetic Dermatology, 2021Partially purified paeoniflorin exerts protective effects on UV-induced DNA damage and reduces facial wrinkles in human skin
Paeonia albiflora flower extract · Journal of Cosmetic Science, 2006Comparative benefit of two thermal spring waters after photodynamic therapy procedure
La roche-posay thermal spring water · Journal of Cosmetic Dermatology, 2007Development of grape seed extract based formulations by using non-invasive biophysical technique and its impact on skin aging
Grape seed oil · Pakistan Journal of Pharmaceutical Sciences, 2021Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders
3-o-ethyl ascorbic acid · Polymers, 2023Preparation, characterization, and application of polysaccharide-based emulsions incorporated with lavender essential oil for skin-friendly cellulosic support
Lavender essential oil · International Journal of Biological Macromolecules, 2021Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast
Squalane · Molecules, 2025Repair of acetone- and sodium lauryl sulphate-damaged human skin barrier function using topically applied emulsions containing barrier lipids
Phytosphingosine · Journal of the European Academy of Dermatology and Venereology, 2002Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol
Sorbitol · Journal of Cosmetic Science, 2013Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration
Betaine · Molecules, 2024Enhanced barrier functions and anti-inflammatory effect of cultured coconut extract on human skin
Coconut fruit extract · Food and Chemical Toxicology, 2017Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment
Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024Efficacy of castor oil cream in treating infraorbital hyperpigmentation: An exploratory single-arm clinical trial
Ricinus communis seed oil castor seed oil · Journal of Cosmetic Dermatology, 2024The protective effect of Artemisia Capillaris Thunb. Extract against UVB-induced apoptosis and inflammation through inhibiting the cGAS/STING pathway
Artemisia capillaris extract · Journal of Photochemistry and Photobiology. B, Biology, 2024Effect of facial application of essence containing royal jelly extract on stratum corneum moisture content: A placebo-controlled, double-blind, parallel-group study
Royal jelly extract · Journal of Cosmetic Dermatology, 2022Topical application of highly concentrated water-in-oil emulsions: Physiological skin parameters and skin penetration in vivo - A pilot study
Isopropyl myristate · International Journal of Pharmaceutics, 2019Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota
Camellia sinensis leaf extract · Molecules, 2024Novel beads made of alpha-cyclodextrin and oil for topical delivery of a lipophilic drug
Glycine soja oil soybean oil · Pharmaceutical Research, 2008Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres
Carica papaya fruit extract · Giornale Italiano Di Dermatologia E Venereologia, 2015Effects of Moringa oleifera Seed Oil on Cultured Human Sebocytes In Vitro and Comparison with Other Oil Types
Moringa oleifera seed oil · International Journal of Molecular Sciences, 2023Comparative measurement of hydration effects of herbal moisturizers
Wheat germ oil · Pharmacognosy Research, 2010Effects of Hydroxydecine(®) (10-hydroxy-2-decenoic acid) on skin barrier structure and function in vitro and clinical efficacy in the treatment of UV-induced xerosis
Royal jelly extract · European Journal of Dermatology, 2011The anti-wrinkles properties of sodium acetylated hyaluronate
Sodium acetylhyaluronate · Journal of Cosmetic Dermatology, 2022Influence of vitamin E acetate on stratum corneum hydration
Tocopheryl acetate, Tocopheryl acetate vitamin e · Arzneimittel-Forschung, 1998A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo
Shea butter · Journal of Cosmetic Dermatology, 2022Topical Almond Oil for Prevention of Pressure Injuries: A Single-Blinded Comparison Study
Prunus amygdalus dulcis oil · Journal of Wound, Ostomy, and Continence Nursing, 2020Anti-inflammatory and skin-hydrating properties of a dietary supplement and topical formulations containing oligomeric proanthocyanidins
Grape seed oil · Skin Pharmacology and Physiology, 2007Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence
Calamine · Biomedicines, 2025Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment
Moringa oleifera seed oil, Moringa seed oil, Moringa oleifera seed extract · Polymers, 2022The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively
Betaine · Skin Research and Technology, 2003A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants
Dimethicone · Ostomy/wound Management, 2005Skin recovery by Lavandula angustifolia leaf callus extract: Redox control of Nrf2 signaling
Lavandula angustifolia oil lavender oil · Free Radical Biology & Medicine, 2025Starch- and carboxymethyl cellulose-based films as active beauty masks with papain incorporation
Carica papaya fruit extract · International Journal of Biological Macromolecules, 2023Clinical Efficacy in Skin Hydration and Reducing Wrinkles of Nanoemulsions Containing Macadamia integrifolia Seed Oil
Macadamia seed oil · Nanomaterials, 2024Combined effects of glycerol and petrolatum in an emollient cream: A randomized, double-blind, crossover study in healthy volunteers with dry skin
Oil · Journal of Cosmetic Dermatology, 2020Highly efficient and compatible shampoo for use after hair transplant
Chamomilla recutita oil flower matricaria oil flower · Clinical, Cosmetic and Investigational Dermatology, 2015Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study
Panthenol, Vitamin b5 · Journal of Cosmetic Dermatology, 2025Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects
Cucumis sativus fruit extract, Cucumbers, Cucumis sativus extract · International Journal of Biological Macromolecules, 2024Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects
Sodium ascorbyl phosphate · Experimental Dermatology, 2012Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer
Galactomyces ferment filtrate pitera ferment filtrate, Rice ferment filtrate sake ferment filtrate · Journal of Clinical Medicine, 2022Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays
Xylitol · Molecules, 2021Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin
Vitamin e · Journal of Cosmetic Dermatology, 2024Development and Evaluation of Cucurbitacin B Microemulsion: the Effect of Oil Phase and Aqueous Phase on Drug Percutaneous Absorption Based on ATR-FTIR Spectroscopy and Molecular Modeling
Cucumis sativus extract · AAPS PharmSciTech, 2020Combination Therapy with Trehalose and Hyaluronic Acid Restores Tear Lipid Layer Functionality by Ameliorating Inflammatory Response Protein Markers on the Ocular Surface of Dry Eye Patients
Trehalose · Journal of Clinical Medicine, 2025Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study
Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026The effect of a vitamin A palmitate and antioxidant-containing oil-based moisturizer on photodamaged skin of several body sites
Retinyl palmitate, Retinyl palmitate vitamin a · Journal of Cosmetic Dermatology, 2013Neuroprotective effects of a new skin care formulation following ultraviolet exposure
Echinacea purpurea root extract · Cell Proliferation, 2012Novel petrolatum-based ointment that is highly moisturizing and has superior usability with increased adherence in patients with facial dry skin
Oil · Journal of Cosmetic Dermatology, 2020Towards a modern approach to traditional use of Helichrysum italicum in dermatological conditions: In vivo testing supercritical extract on artificially irritated skin
Helichrysum italicum callus extract · Journal of Ethnopharmacology, 2023Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009Macadamia Nuts Oil in Nanocream and Conventional Cream as Skin Anti-Aging: A Comparative Study
Macadamia ternifolia oil nut macadamia oil nut · Open Access Macedonian Journal of Medical Sciences, 2019Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum
Caprylic capric triglyceride, Glyceryl tri caprylate caprate · Life, 2023Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy
Tocopheryl acetate, Tocopheryl acetate vitamin e · Scientific Reports, 2025The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A Prospective, Observational Study
3-ceramide blend · Journal of Cosmetic Dermatology, 2025Hippophae rhamnoides oil-in-water (O/W) emulsion improves barrier function in healthy human subjects
Hippophae rhamnoides oil · Pakistan Journal of Pharmaceutical Sciences, 2014Development and efficacy assessments of tea seed oil makeup remover
Camellia sinensis seed oil · Annales Pharmaceutiques Francaises, 2017Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris
Citric acid · Journal of Drugs in Dermatology, 2013Treatment of Stretch Marks Using a New Formulation Combining Nanofractional Radiofrequency Plus Magnetic Nanofractional Radiofrequency
Beta-glucan · Dermatology and Therapy, 2023Assessment of Skin Photoallergy Risk in Cosmetics Containing Herbal Extract Ingredients
Lithospermum erythrorhizon root extract · Skin Pharmacology and Physiology, 2021Functional properties and skin care effects of sodium trehalose sulfate
Trehalose · Skin Research and Technology, 2024Transdermal Delivery of Baicalin Based on Bio-Vesicles and Its Efficacy in Antiaging of the Skin
Scutellaria baicalensis root extract · Journal of Cosmetic Dermatology, 2025In vitro, ex vivo and clinical approaches to evaluate the potential effect of Gentiana lutea extract on skin
Gentiana lutea extract · International Journal of Cosmetic Science, 2023Lemon Balm (Melissa officinalis L.) Leaf Extract Promotes Endo180 Production in Dermal Fibroblasts and has Antiwrinkle Effect on Human Skin
Melissa officinalis leaf extract · Photodermatology, Photoimmunology & Photomedicine, 2025Dirt-binding particles consisting of hydrogenated castor oil beads constitute a nonirritating alternative for abrasive cleaning of recalcitrant oily skin contamination in a three-step programme of occupational skin protection
Ricinus communis seed oil castor seed oil, Castor oil · The British Journal of Dermatology, 2010Development of nanofiber facial mask inspired by the multi-function of dried ginger (Zingiberis Rhizoma) essential oil
Zingiber officinale oil root · Scientific Reports, 2025Chitosan derivative nanocarrier: safety evaluation,antibacterial property and ascorbyl palmitate encapsulation
Ascorbyl palmitate · Journal of Microencapsulation, 2010A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females
Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial
Tocopheryl acetate, Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021Evolution of lipid composition in skin treated with blackcurrant seed oil
Ribes nigrum seed oil · International Journal of Cosmetic Science, 1988Rapid and Visible Efficacy of a Dermocosmetic in Acne Patients With Fair Skin Phototypes: Results of a Randomized Split-Face Study
Zinc gluconate · Journal of Cosmetic Dermatology, 2026Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study
Galactomyces ferment filtrate pitera ferment filtrate · Journal of Clinical Medicine, 2023Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin
Camellia sinensis seed oil · International Journal of Cosmetic Science, 2026Skin moisturization by hydrogenated polyisobutene--quantitative and visual evaluation
Hydrogenated polyisobutene · Journal of Cosmetic Science, 2009The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study
Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024Effects of Malaysian thermal spring water as adjunct therapy for mild to moderate acne vulgaris - a prospective, randomised, controlled, split face study
La roche-posay thermal spring water · The Medical Journal of Malaysia, 2024Investigating the Effects of a Manuka Honey, Royal Jelly, and Bee Venom-Derived Face Serum on Skin Health and Signs of Aging
Manuka honey, Royal jelly extract · Cureus, 2025A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties
Soybean seed extract · Skin Research and Technology, 2026The effect of different formulations of equivalent active ingredients on the performance of two topical wound treatment products
Castor oil · Ostomy/wound Management, 2004Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial
Shea butter, Argania spinosa kernel oil, Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025Interest in Micellar Solution to Reduce Unpleasant Skin Sensations
Micellar technology · Clinical, Cosmetic and Investigational Dermatology, 2021Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial
Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color
Galactomyces ferment filtrate pitera ferment filtrate · Skinmed, 2021Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking
Palmitoyl tetrapeptide-7 · International Journal of Cosmetic Science, 2026Evaluation of Saponin-Rich Callus from Saponaria officinalis L. as a Novel Scrub Material with Significant Exfoliating and Anti-Inflammatory Effects
Soap grass extract, Saponaria officinalis leaf extract · Plants, 2025Clinical Evaluation of a Soap-Free Cleansing Lotion Containing Sodium Cocoyl Apple Amino Acids for Effective Impurity Removal and Skin Barrier Preservation in Healthy Adults With Diverse Skin Types
Cetyl alcohol · Cureus, 2025Dermatological Effects of a Beeswax-Pine Resin Mixture on Abdominal Skin: A Proof-of-Concept Study Supporting the Development of an Affordable Investigational Ostomy Pouching System in Low-Income Regions
Beeswax · Journal of Wound, Ostomy, and Continence Nursing, 2026Safety data on single application of emu and macadamia nut oil on human skin
Macadamia ternifolia oil nut macadamia oil nut · Data in Brief, 2017Combined Effect of Silybin and Sodium Acetylated Hyaluronate on UV-Induced Photoaging
Sodium acetylhyaluronate · Skin Research and Technology, 2026