Theramid DERMA-PEPTIDES for dry sensitive skin
Palmitoyl Tripeptide-1
Sh-Oligopeptide-1
Palmitoyl Tetrapeptide-7
Average
- HighDry Skin Fit
- HighEffectiveness
- HighSafety
Works for dry sensitive skin; other moisturizers fit it better.
- International Journal of Cosmetic Science, 2024
- Clinical, Cosmetic and Investigational Dermatology, 2017
This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent moisturizing for your dry skin, as glycerin and propanediol effectively draw water into the skin to hydrate and plump.
- The inclusion of Palmitoyl Tripeptide-1 provides supportive benefits for dry or flaky skin by enhancing hydration.
- The product is safe for your dry and sensitive skin, with no risks of irritation due to the absence of harsh ingredients.
How to apply
- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
People Say
★4.7Overall rating based on 300+ reviewsUsers frequently praise this serum for its lightweight, non-sticky texture and its effectiveness in delivering visible anti-aging results, such as increased skin plumpness and reduced fine lines. It is also noted for its gentle, fragrance-free formulation, making it suitable for sensitive skin and compatible with other active ingredients.
Highlights
Visible anti-aging Mostly Mentioned
- “Fine lines are less visible”
- “Skin looks plumper”
- “More youthful skin”
Gentle formulation Often Mentioned
- “Suitable for sensitive skin”
- “No strong scent”
- “No sensitising occurring”
Lightweight texture Often Mentioned
- “Absorbs quickly”
- “Doesn't leave stickiness”
- “Lotion-like texture”
Good value Sometimes Noted
- “Price is unbeatable”
- “Affordable serums”
- “Quality for price”
Practical packaging Sometimes Noted
- “Love the pump”
- “Pipettes are annoying”
- “Packaging pleases senses”
High expectations Rarely Noted
- “Overhyped by influencers”
- “Waiting for results”
- “Not a miracle”
Limited availability Rarely Noted
- “Hard to find in stores”
- “Only online”
- “Shipping delays”
Packaging preference Rarely Noted
- “Prefer glass bottles”
- “Pump can clog”
- “Hard to see level”
Sources: lovi.care, nichebeautylab.com, skintskincare.com, reddit.com, youtube.com, and more
Questions and answers
How well does Theramid Derma-Peptides work for dry sensitive skin?
Theramid Derma-Peptides works for your dry sensitive skin, though other products fit it better. It helps draw water in to hydrate and plump your dry skin while keeping irritation unlikely. To fit this skin best, a moisturizing treatment needs multiple forms of hyaluronic acid, pro vitamin B5, and ceramides for deep and lasting hydration and barrier support.
International Journal of Cosmetic Science, 2024Clinical, Cosmetic and Investigational Dermatology, 2017
Which ingredients make this cream a good fit for dry sensitive skin?
Glycerin, propanediol, and Palmitoyl Tripeptide-1 make this cream a good fit by drawing water into the skin, enhancing hydration, and supporting dry or flaky areas without causing irritation. To reach the highest level of fit for dry sensitive skin, a product of this type needs multiple forms of hyaluronic acid, pro vitamin B5, and ceramides to provide intense hydration, nourishment, and barrier support.
What does Palmitoyl Tripeptide-1 do for dry sensitive skin?
Palmitoyl tripeptide-1 helps firmness and smooths fine lines, and it is best paired with a gentle moisturizer to keep dry sensitive skin comfortable. Because it supports collagen, it may improve skin texture over time while remaining gentle enough for daily use.
Journal of Cosmetic Dermatology, 2026International Journal of Cosmetic Science, 2026
What does EGF do for dry sensitive skin?
EGF helps calm dry sensitive skin by supporting skin repair and renewal, though it may need to be paired with rich moisturizers and soothing ingredients to properly comfort very dry or reactive areas.
Where does this cream go in a skincare routine for dry sensitive skin?
This treatment goes in the evening routine after your toner and before your moisturizer. It is unlikely to cause irritation on dry and sensitive skin, but this skin type often needs richer lipid-replenishing ingredients and barrier-supporting ceramides to feel fully comfortable.
Can I use this cream with retinol, and in what order?
You can use this treatment with retinol by applying the retinol first and following with this cream to help keep your dry skin calm and hydrated. Because your skin is dry and sensitive, using a gentle moisturizer with soothing ingredients and skin barrier repair components is also helpful when using strong products like retinol.
How often should I use this cream?
THERAMID DERMA-PEPTIDES works well in your evening routine as a moisturizing treatment for dry sensitive skin. Daily application helps keep your skin soft and hydrated, though this skin type needs extra soothing and barrier-repairing ingredients for an ideal fit.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this cream clog pores, cause breakouts or purging for dry sensitive skin?
This cream is unlikely to clog pores, cause breakouts, or lead to purging on dry sensitive skin. It features gentle moisturizing ingredients like glycerin and propanediol that hydrate without heavy oils, keeping your skin safe from irritation.
Can I use this cream around the eyes or on my body?
You can use this cream on your body and around your eyes, as it is safe for dry and sensitive skin. Because the skin around the eyes is very thin, a product of this type needs gentle hydrating ingredients like glycerin and soothing peptides to protect and hydrate without irritation.
Surgical and Radiologic Anatomy, 2002International Journal of Cosmetic Science, 2024
What the research says
Topical application of 1,3-propanediol at various concentrations, alone or combined with butylene glycol and/or glycerol, increased skin hydration and reduced trans epidermal water loss in 30 healthy female subjects over an 8-hour period, with the 15% concentration and the addition of glycerol providing greater benefits.
International Journal of Cosmetic Science, 2024A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.
Journal of Cosmetic Dermatology, 2026A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.
Journal of Cosmetic Dermatology, 2015Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.
International Journal of Cosmetic Science, 2026Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone.
The New England Journal of Medicine, 1989Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba.
Lasers in Surgery and Medicine, 2020Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars.
The Journal of Clinical and Aesthetic Dermatology, 2022
Ingredients
Water, Glycerin, Propanediol, Caprylic Capric Triglyceride, Palmitoyl Tripeptide-1, Sh-Oligopeptide-1, Palmitoyl Tetrapeptide-7
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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