Theramid DERMA-PEPTIDES for combination skin
Palmitoyl Tripeptide-1
Sh-Oligopeptide-1
Palmitoyl Tetrapeptide-7
Low
- HighCombination Skin Fit
- AverageEffectiveness
- HighSafety
A weak match for combination skin; the moisturizers alongside fit it better.
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate moisturizing due to the presence of glycerin and propanediol, which hydrate combination skin, but the peptides like Palmitoyl Tripeptide-1 and Sh-Oligopeptide-1 are not specialized for your oily shine concerns.
- While the peptides support collagen stimulation and extracellular matrix synthesis, which is beneficial for combination skin, the formula does not offer targeted solutions for oil control.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
People Say
★4.7Overall rating based on 300+ reviewsUsers frequently praise this serum for its lightweight, non-sticky texture and its effectiveness in delivering visible anti-aging results, such as increased skin plumpness and reduced fine lines. It is also noted for its gentle, fragrance-free formulation, making it suitable for sensitive skin and compatible with other active ingredients.
Highlights
Visible anti-aging Mostly Mentioned
- “Fine lines are less visible”
- “Skin looks plumper”
- “More youthful skin”
Gentle formulation Often Mentioned
- “Suitable for sensitive skin”
- “No strong scent”
- “No sensitising occurring”
Lightweight texture Often Mentioned
- “Absorbs quickly”
- “Doesn't leave stickiness”
- “Lotion-like texture”
Good value Sometimes Noted
- “Price is unbeatable”
- “Affordable serums”
- “Quality for price”
Practical packaging Sometimes Noted
- “Love the pump”
- “Pipettes are annoying”
- “Packaging pleases senses”
High expectations Rarely Noted
- “Overhyped by influencers”
- “Waiting for results”
- “Not a miracle”
Limited availability Rarely Noted
- “Hard to find in stores”
- “Only online”
- “Shipping delays”
Packaging preference Rarely Noted
- “Prefer glass bottles”
- “Pump can clog”
- “Hard to see level”
Sources: lovi.care, nichebeautylab.com, skintskincare.com, reddit.com, youtube.com, and more
Questions and answers
Why is Theramid Derma-Peptides a weak match for combination skin?
THERAMID DERMA-PEPTIDES is a weak match for combination skin because it provides moderate moisture with glycerin and propanediol but lacks targeted oil control for your oily shine concerns. A moisturizing treatment for this skin type needs effective hydrating and skin-repairing ingredients like ceramides, hyaluronic acid, and niacinamide to balance moisture and manage oil.
International Journal of Cosmetic Science, 2024Journal of Cosmetic Dermatology, 2026
Which ingredients make this treatment a poor fit for combination skin?
This treatment is a weak match because the peptides like Palmitoyl Tripeptide-1 and Sh-Oligopeptide-1 are not specialized for your oily shine concerns. A moisturizing treatment for this skin needs ingredients like ceramides, hyaluronic acid, and niacinamide to balance moisture and control oil.
Journal of Cosmetic Dermatology, 2026International Journal of Cosmetic Science, 2026
What does Palmitoyl Tripeptide-1 do for combination skin?
Palmitoyl tripeptide-1 helps smooth fine lines and supports firmness in combination skin when used as part of an anti-aging routine. Studies show that ingredients like this peptide can improve overall skin texture and boost collagen levels when applied consistently over time.
Journal of Cosmetic Dermatology, 2026International Journal of Cosmetic Science, 2026
What does EGF do for combination skin?
EGF helps support cell turnover and collagen production, which may improve firmness and keep combination skin looking smooth and even. For the best results on combination skin, this ingredient works well alongside hydrating ingredients like hyaluronic acid to balance oilier and dry areas.
Journal of Drugs in Dermatology, 2019Cell Proliferation, 2022
Where does it go in a skincare routine for combination skin?
This treatment goes in the evening routine after cleansing and before your moisturizer, used carefully as a weak match for combination skin that lacks oil control. A product of this type for combination skin needs balancing ingredients and oil-control agents to manage shine while hydrating.
Can I use this treatment with retinol, and in what order?
You can use this treatment with retinol by applying the treatment after your retinol has absorbed into your skin. While it provides gentle hydration with glycerin and propanediol, it lacks the oil-controlling ingredients that combination skin needs.
How often should I use it?
You can use this treatment in the evening as part of your routine. It is safe for your skin and is unlikely to cause irritation.
Can it clog pores, cause breakouts or purging for combination skin?
This product is unlikely to clog pores or cause breakouts for combination skin, as it lacks harsh ingredients and is safe for your skin type. However, a product for this skin needs oil-balancing and shine-controlling ingredients to manage excess oil effectively.
Can I use this treatment around the eyes or on my body?
You can safely use this moisturizing treatment on the thin skin around your eyes and on your body because its formula is gentle and free of harsh ingredients. However, a product of this type needs targeted oil control and balancing ingredients to properly care for combination skin.
Surgical and Radiologic Anatomy, 2002Journal of Cosmetic Dermatology, 2015
What the research says
Topical application of 1,3-propanediol at various concentrations, alone or combined with butylene glycol and/or glycerol, increased skin hydration and reduced trans epidermal water loss in 30 healthy female subjects over an 8-hour period, with the 15% concentration and the addition of glycerol providing greater benefits.
International Journal of Cosmetic Science, 2024A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.
Journal of Cosmetic Dermatology, 2015Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.
Journal of Cosmetic Dermatology, 2026Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.
International Journal of Cosmetic Science, 2026Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone.
The New England Journal of Medicine, 1989Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba.
Lasers in Surgery and Medicine, 2020Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars.
The Journal of Clinical and Aesthetic Dermatology, 2022
Why other moisturizers fit combination skin better
A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.
Journal of Cosmetic Dermatology, 2024A peel-off facial mask containing myoinositol and trehalose-loaded liposomes improved adult female acne by decreasing lesion counts, sebum production, GAGS scores, and local androgen levels while increasing beclin-1 levels.
Journal of Cosmetic Dermatology, 2017Gluconolactone chemical peels lower skin pH and transepidermal water loss while demonstrating seboregulatory properties in 16 female subjects.
Journal of Cosmetic Dermatology, 2023
Ingredients
Water, Glycerin, Propanediol, Caprylic Capric Triglyceride, Palmitoyl Tripeptide-1, Sh-Oligopeptide-1, Palmitoyl Tetrapeptide-7
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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