SK-II Facial Treatment Clear Lotion for combination skin

How to apply

Questions and answers

What the research says

• Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability.

  Journal of Cosmetic Dermatology, 2024

• A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase.

  BioMed Research International, 2020

• Application of Galactomyces ferment filtrate skin care formula significantly reduced the net values and daily fluctuation of facial pore area, roughness, and redness in young Japanese women.

  Journal of Clinical Medicine, 2021

• Daily application of Galactomyces ferment filtrate-containing skin products for 12 months significantly and cumulatively reversed 11-year facial skin aging parameters of wrinkles, hyperpigmented spots, and roughness, and increased skin hydration in 86 female volunteers.

  Journal of Clinical Medicine, 2023

• A combination serum containing galactomyces ferment filtrate, dexpanthenol, and Centella asiatica effectively treated post-acne hyperpigmentation in subjects with colored skin by significantly increasing lightness scores in Fitzpatrick skin type V and reducing the melanin index in Fitzpatrick skin type IV compared to placebo.

  Skinmed, 2021

• Galactomyces ferment filtrate promotes epidermal interconnectivity, barrier development, cell adhesion, keratinocyte differentiation and proliferation, and protects cellular bioenergetics against stress in keratinocytes and ex vivo skin explants compared to untreated controls.

  International Journal of Cosmetic Science, 2024

• Galactomyces ferment filtrate activates AHR and NRF2, upregulates filaggrin and terminal differentiation markers, exhibits antioxidative activity, promotes antiinflammatory IL-37, and downregulates CDKN2A, IL-33, CXCL14, and IL6R in epidermal keratinocytes.

  Journal of Clinical Medicine, 2022

• Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients.

  CMAJ, 2010

• Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy.

  Journal of Cosmetic Dermatology, 2024

• Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients.

  Journal of the American Academy of Dermatology, 2010

• Application of a cream containing lactic acid 12% and pramoxine HCl 1% significantly improved skin dryness, hydration, and itch compared with a nontreated control in 24 women with a history of dry itchy skin.

  Cutis, 2004

• Topical 12% ammonium lactate produced a significant sparing of epidermal and dermal atrophy induced by clobetasol propionate in human volunteers, without influencing the corticosteroid's bioavailability or antiinflammatory properties.

  Journal of the American Academy of Dermatology, 1992

• A lactic acid/ceramide lotion significantly improved skin moisturization and desquamation compared to no treatment in women with dry, rough skin on the anterior shins.

  The Journal of Clinical and Aesthetic Dermatology, 2020

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

Ingredients

Water, Galactomyces Ferment Filtrate Pitera Ferment Filtrate, Butylene Glycol, Polysorbate 20, Glycerin, Sodium Hyaluronate, Peg-150, Cellulose Gum, Disodium Edta, Citric Acid, Salicylic Acid, Lactic Acid, Malic Acid, Sodium Citrate, Sodium Benzoate, Methylparaben

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.