Rodial Vitamin C Drops for skin with dark spots

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Questions and answers

What the research says

• Treatment with ascorbyl glucoside-arginine complex lotion significantly decreased pigmentation scores and melanin index while increasing lightness in solar lentigos of Japanese females compared to placebo over 24 weeks.

  International Journal of Molecular Sciences, 2024

• Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

  Journal of Periodontology, 2009

• A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.

  The Journal of Dermatological Treatment, 2017

• Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

  American Journal of Clinical Dermatology, 2002

• Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

  Experimental Dermatology, 2003

• Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

  Journal of Cosmetic Dermatology, 2022

• Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline.

  Experimental Dermatology, 2008

• Hydrogel-conditioned nanostructured lipid carriers incorporating carrot extract, marigold extract, and azelaic acid improved antioxidant, anti-inflammatory, and anti-acne responses in treated subjects, achieving enhanced skin hydration up to 74% and elasticity up to 90% without adverse effects.

  Materials Science & Engineering. C, Materials for Biological Applications, 2020

• Topical beta-carotene provided protection for the human skin of healthy volunteers against IR radiation by acting as a superficial antioxidant, though dermal carotenoid degradation was significantly higher for standard infrared radiator than for water filter infrared irradiation.

  Experimental Dermatology, 2011

• Beta-carotene at low concentrations significantly decreased the major metabolites of arachidonic acid and linoleic acid in human epidermal homogenates and inhibited 13-hydroxy-cis-9, trans-11-octadeca dienoic acid formation by up to 80% compared with the control in a semi-in vivo skin penetration model.

  The International Journal of Biochemistry & Cell Biology, 1996

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.

  Arzneimittel-Forschung, 2000

• Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.

  Auris, Nasus, Larynx, 2020

Ingredients

Water, Butylene Glycol, Babassu Glycereth-8 Esters Oil, Ascorbyl Glucoside, Olive Peg-7 Esters Oil, Almond Peg-8 Esters Oil, Peg-40 Hydrogenated Castor Oil, Phenoxyethanol, Ammonium Acryloyldimethyltaurate Vp Copolymer, Panthenol, Benzyl Alcohol, Sodium Hydroxide, Helianthus Annuus Seed Oil Sunflower Seed Oil, Disodium Edta, Ethylhexylglycerin, Parfum, Limonene, Dehydroacetic Acid, Geraniol, Linalool, Beta-Carotene, Daucus Carota Sativa Root Extract Carrot Root Extract, Daucus Carota Sativa Seed Oil Carrot Seed Oil, Ascorbyl Palmitate

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.