Peter Thomas Roth Retinol Fusion PM Night Serum for mature skin
Microencapsulated Retinol
Vitamins C
Squalane
Bisabolol
Cyclopentasiloxane
Average
- SuperiorNormal Skin Fit
- AverageEffectiveness
- HighSafety
Works for mature skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate treatment for minimizing fine lines and wrinkles due to the presence of retinol, which promotes skin renewal, and provides general hydration benefits from squalane and bisabolol that are supportive for normal skin.
- The formulation is excellent for normal skin, with retinol regulating cell turnover and squalane and tocopheryl acetate providing emollient and antioxidant actions.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing bisabolol.
How to apply
- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
People Say
★4.5Overall rating based on 4.7k+ reviewsBased on a very large amount of data, this retinol serum is highly regarded for its anti-aging effects, including smoothing fine lines and improving skin texture, with most users experiencing a radiant and refined complexion without irritation. Some users reported a lack of visible results or found the thin consistency and premium price point to be drawbacks.
Highlights
Non-irritating formula Mostly Mentioned
- “Zero irritation”
- “gentle but effective”
- “no peeling or flaking”
Reduces fine lines Often Mentioned
- “Smile lines fading”
- “fine lines disappeared”
- “wrinkles nearly gone”
Smoother texture Often Mentioned
- “Skin is softer”
- “smoother complexion”
- “refined skin texture”
Absorbs quickly Sometimes Noted
- “Soaks in quickly”
- “dries quickly”
- “silky smooth application”
Radiant complexion Sometimes Noted
- “Face is brighter”
- “skin is radiant”
- “luminous appearance”
High price point Sometimes Noted
- “Not worth it”
- “very pricey”
- “expensive for the results”
Lack of results Sometimes Noted
- “No visible changes”
- “did absolutely nothing”
- “no change in skin”
Oily feel Rarely Noted
- “Feels oily”
- “greasy application”
- “leaves residue”
Thin consistency Rarely Noted
- “Very, very watery”
- “feels like dry oil”
- “too thin”
Sources: lovi.care, peterthomasroth.com, ulta.com, dermstore.com, lovelyskin.com, macys.com, and more
Questions and answers
How well does Peter Thomas Roth Retinol Fusion PM Night Serum work for mature skin?
Peter Thomas Roth Retinol Fusion PM Night Serum works decently for mature skin, helping to smooth fine lines with retinol while keeping skin soft with squalane and bisabolol. A product of this type needs high concentrations of potent antioxidants, peptides, and humectants that exceptionally target wrinkles and improve skin elasticity for mature skin.
Which ingredients make this serum a good fit for mature skin?
Microencapsulated retinol helps smooth fine lines by encouraging skin renewal, while squalane and bisabolol keep the skin soft and calm. To best support mature skin, a product of this type needs high concentrations of potent anti-aging ingredients, powerful antioxidants, and deeply hydrating components that effectively target wrinkles while maintaining excellent safety and suitability.
What does Microencapsulated Retinol do for mature skin?
Microencapsulated retinol helps smooth fine lines and even out dark spots on mature skin while typically causing less irritation than standard retinol. It works gradually to improve the look of aging skin, though it may still cause mild dryness or flaking.
Journal of Controlled Release, 2018Clinical Interventions in Aging, 2006
What does Vitamin C do for mature skin?
Vitamin C helps mature skin by smoothing fine lines and wrinkles while improving firmness and overall radiance. It supports the skin by boosting collagen production and providing antioxidant protection against daily damage.
Journal of Cosmetic Dermatology, 2020Journal of Cosmetic Dermatology, 2023
Where does it go in a skincare routine for mature skin?
This treatment goes in the evening routine after cleansing and before moisturizing. Putting treatments in the evening helps with simplicity and extra safety around sun exposure.
Can I use this serum with niacinamide, and in what order?
You can use this serum with niacinamide by applying niacinamide first, letting it absorb, and then following with this serum. This type of skin needs ingredients that provide stronger anti-aging benefits and deeper hydration to effectively smooth fine lines and plump mature skin.
How often should I use it?
Apply this treatment in the evening as part of your routine. This product of this type needs regular use to help smooth fine lines, alongside ingredients like concentrated retinoids and rich moisturizers to better support mature skin.
Can it clog pores, cause breakouts or purging for mature skin?
This serum is unlikely to clog pores or cause breakouts on mature skin, but the retinol in it may cause some initial skin purging as it speeds up cell renewal. Because this product is only an average fit for mature skin, a routine for this skin type typically needs stronger anti-aging ingredients and richer moisturizers to better smooth fine lines.
Is this serum fragrance-free and alcohol-free?
It has no fragrance and contains drying alcohol (alcohol).
What the research says
Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging.
The British Journal of Dermatology, 2019Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle.
International Journal of Cosmetic Science, 2017Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity.
Journal of Controlled Release, 2018Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle.
Archives of Dermatological Research, 2017Topical application of all-trans-retinol induced epidermal thickening and increased retinoid binding protein expression similar to all-trans-retinoic acid in normal human skin, but without causing significant erythema or measurable retinoic acid levels.
The Journal of Investigative Dermatology, 1995Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.
Journal of Cosmetic Dermatology, 2022Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025Application of an alpha-bisabolol-containing cream produced a significant skin-lightening effect in pigmented skin compared to a vehicle control in the majority of female subjects after 8 weeks.
International Journal of Cosmetic Science, 2010The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate reduces UVB-induced PGE2, inflammatory cytokines, and mitochondrial superoxide in human epidermal keratinocytes.
International Journal of Cosmetic Science, 2024
Ingredients
Cyclopentasiloxane, Squalane, Water, Retinol, Tocopheryl Acetate, Ascorbyl Palmitate, Bisabolol, Lecithin, Potassium Phosphate, Pentylene Glycol, Polysorbate-20, Alcohol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-
Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-
Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-
Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-
Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-
Medical Board
Cosmetic chemist, SCS, IFSCC member
-
Medical Board, Medical Advisor
Dermatology MD
-
Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-
Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.