PanOxyl PM Overnight Spot Patches for acne-prone skin
Hydrocolloid Dressing
Glycerin
Dimethicone
Sodium Chloride
Xanthan GumAverage
- HighCombination Skin Fit
- AverageEffectiveness
- HighSafety
Works for acne-prone skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate benefits for your combination skin, as glycerin and dimethicone help balance hydration and texture without increasing oiliness.
- The hydrocolloid dressing effectively absorbs exudate and protects acne blemishes, providing excellent spot treatment for your breakouts.
- The product is safe for your combination skin, with no risks of irritation due to the absence of harsh ingredients.
How to apply
- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
People Say
★4.5Overall rating based on 22.0k+ reviewsBased on a very large amount of data, users with acne-prone and sensitive skin widely praise these hydrocolloid patches for effectively flattening whiteheads and absorbing fluids overnight while preventing skin picking. Results are mixed for deep cystic acne, and some users find the patches slightly thicker than competitors, making them better suited for nighttime use.
Highlights
Absorbs fluid effectively Mostly Mentioned
- “Sucked up all the gunk in that pimple near my nose”
- “By morning the white head is pulled out”
- “Patches would fill with gunk so fast”
- “Flattened the pimple literally overnight”
Prevents skin picking Often Mentioned
- “Helpful to prevent her from picking”
- “Keeps me from touching my face”
- “Stops me from making it worse by popping”
- “Great barrier against my wandering hands”
Good value for money Sometimes Noted
- “More quantity for the price than other brands”
- “Cheaper than Mighty Patch and works just as well”
- “Best inexpensive pimple patches I have tried”
- “Good amount for the price”
Strong overnight adhesion Sometimes Noted
- “Stays on well throughout the night”
- “Adhere really well even on top of moisturizer”
- “Don't budge while I sleep”
- “Stuck on until the morning”
Ineffective on cystic acne Sometimes Noted
- “Didn't do anything for my cystic acne”
- “Not suitable for inflamed pimples under the skin”
- “Only works on the right kind of pimple, not deep zits”
- “Useless for blind pimples”
Adhesion residue Rarely Noted
- “Adhesive is a bit hard to wash off”
- “Left a sticky residue in the morning”
- “Leaves a tiny red mark from sticking so hard”
- “Hard to remove without pulling skin”
Difficult packaging Rarely Noted
- “Packaging is impossible to open”
- “Patches get stuck on the plastic as you tear it”
- “Hard to peel off the backing sheet”
- “Aggravating to get out of the packet”
Too thick/visible Rarely Noted
- “Slightly thicker than other alternatives”
- “Visible on skin, definitely for PM use”
- “Not as invisible as other brands”
- “Can see the edges clearly”
Sources: lovi.care, target.com, iherb.com, ulta.com, walmart.com, hometesterclub.com, and more
Questions and answers
How well does PanOxyl PM Overnight Spot Patches work for acne-prone skin?
PanOxyl PM Overnight Spot Patches works moderately well for acne-prone skin by protecting blemishes and absorbing fluid with its hydrocolloid dressing, while glycerin and dimethicone help balance hydration without adding oiliness. Acne-prone skin needs targeted treatments that clear breakouts while also providing balanced hydration and soothing ingredients to keep the skin comfortable.
Which ingredients make this patch a good fit for acne-prone skin?
The hydrocolloid dressing makes these patches a great fit by absorbing fluid and protecting breakouts, while glycerin and dimethicone help balance hydration without adding oil. This type of product needs targeted acne-fighting ingredients combined with balanced hydrators to care for acne-prone skin effectively.
What does Hydrocolloid Dressing do for acne-prone skin?
Hydrocolloid Dressing helps calm acne-prone skin by reducing overall breakouts, inflammation, redness, and oiliness. It works well for treating acne vulgaris and supports healing by managing sebum levels.
Journal of Cosmetic Science, 2006Journal of Clinical Medicine, 2025
What does Glycerin do for acne-prone skin?
Glycerin helps keep acne-prone skin hydrated and calm without clogging pores or feeling heavy. It supports the skin barrier so it stays soft and smooth while handling everyday treatments.
The British Journal of Dermatology, 2008International Journal of Toxicology, 2019
Where does this patch go in a skincare routine for acne-prone skin?
This patch goes in the evening routine after cleansing and toning, right before your moisturizer. Acne-prone skin of this type needs spot treatments with a hydrocolloid dressing to protect blemishes and glycerin and dimethicone to balance hydration and texture without adding oil.
Can I use this patch with salicylic acid, and in what order?
You can use this patch in the same routine as salicylic acid by applying your salicylic acid treatment first, letting it dry completely, and then placing the patch directly over the blemish. This approach lets the salicylic acid clear out the pore while the patch protects the spot and absorbs fluid without causing extra irritation.
How often should I use this patch?
PanOxyl PM Overnight Spot Patches work well as an overnight spot treatment for your breakouts, protecting blemishes while you sleep. To get the best results for acne-prone skin, this type of product needs ingredients like hydrocolloid dressings to absorb fluid and protect the skin.
Can this patch clog pores, cause breakouts or purging for acne-prone skin?
This patch is unlikely to clog pores, cause breakouts, or lead to purging on acne-prone skin, as it has a safe formula with no harsh ingredients. However, because it offers only moderate benefits, acne-prone skin often needs products with stronger active ingredients like salicylic acid or benzoyl peroxide to truly clear and prevent breakouts.
Is this patch fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017A topical xanthan gum nanogel containing gamma-oryzanol-loaded nanostructured lipid carriers and nanosized TiO2 and MBBT filters demonstrated high photoprotection with an SPF of 34 and no skin irritation or sensitization in a rat model.
Pharmaceuticals, 2023Daily application of hydrocolloid dressing completely prevented nasogastric tube-related pressure injuries, whereas skin care interventions showed no significant preventive effect compared to the control group in intensive care unit patients.
Journal of Tissue Viability, 2024Hydration of scars for 2 months resulted in significantly reduced itching, somewhat reduced pain, and increased pliability by 10% for both hydrocolloid dressing and moisturizer treatments in patients with keloids or hypertrophic scars, with no change in physical parameters.
Dermatologic Surgery, 1996Adjunctive hydrocolloid dressing with 0.1% mometasone furoate cream significantly increased treatment efficacy and cost-effectiveness compared to topical steroid alone in patients with moderate to severe lichen simplex chronicus.
Skin Health and Disease, 2023The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups.
Military Medicine, 2024A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate.
Skin Research and Technology, 2000Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms.
Clinical and Experimental Dermatology, 2007Calcium hydroxylapatite diluted with normal saline combined with microfocused ultrasound with visualization improved age-related changes in the lower face, neck, and décolleté and stimulated collagen and elastin fibers in 20 subjects.
Journal of Drugs in Dermatology, 2020Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.
Auris, Nasus, Larynx, 2020Topical application of magnetized saline water serum improved skin hydration, reduced transepidermal water loss, sebum content, melanin index, and erythema index, and activated autophagy by increasing Beclin-1 and decreasing mTOR in females wanting to enhance facial and neck skin appearance.
Cureus, 2023Biodegradable wound dressings functionalized with silver nanoparticles showed >99% pathogen growth inhibition, bactericidal effects, free radical scavenging, reduced inflammatory response in macrophages, and accelerated wound healing in animals.
International Journal of Biological Macromolecules, 2022Dense chitosan-xanthan membranes associated with multipotent mesenchymal stromal cells accelerated wound healing in Wistar rats compared to untreated conditions, demonstrating safety and feasibility for dermo-epidermal wound treatment.
Journal of Biomaterials Applications, 2015Glycerol crosslinked vitamin E loaded xanthan gum and gellan gum nanoemulgels scavenged 88.5% of free radicals, reduced transepidermal water loss by up to 33.3%, and improved moisture content and skin structural characteristics in a murine dry skin model.
International Journal of Biological Macromolecules, 2025
Ingredients
Hydrocolloid Dressing, Carbomer Homopolymer Type C, Carbomer Interpolymer Type A, Decyl Glucoside, Dimethicone, Dioctyl Sodium Sulfosuccinate, Glycerin, Palmitic Acid, Polyacrylate Crosspolymer-6, Polyoxyl 40 Stearate, Propanediol, Water, Silica, Sodium Chloride, Sodium Citrate, Sodium Hydroxide, Sodium Laurylglucosides Hydroxypropylsulfonate, Sorbitan Stearate, Stearic Acid, T-Butyl Alcohol, Xanthan Gum
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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