ma:nyo Bifida Complex Ampoule for oily skin
Bifidobacterium Lysate Ferment Bifidalacto Complex Ferment
Niacinamide
Lactobacillus Pumpkin Fruit Ferment Filtrate
Panax Ginseng Root Extract
Sodium Hyaluronate
Average
- HighOily Skin Fit
- AverageEffectiveness
- HighSafety
Works for oily skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent skin barrier resilience for your oily skin due to the presence of Bifida Lysate Ferment and Lactobacillus Pumpkin Fruit Ferment Filtrate, which support hydration and soothing, though these benefits are not directly targeted at managing oily shine.
- Niacinamide and caffeine are included for seboregulation and vasoconstrictive effects, providing general skincare benefits relevant to oily skin.
- The formula is safe for your oily skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
Questions and answers
How well does ma:nyo Bifida Complex Ampoule work for oily skin?
This ampoule works moderately well for oily skin by supporting your skin barrier and helping calm the skin, though it does not directly manage oily shine. To work best for oily skin, a product of this type needs ingredients like niacinamide and zinc PCA to control excess oil and pores, alongside lightweight hydrators that keep skin comfortable.
Which ingredients make this serum a good fit for oily skin?
Niacinamide and caffeine help manage oily shine, while Bifida Lysate Ferment and Lactobacillus Pumpkin Fruit Ferment Filtrate support hydration and soothing for your oily skin. For a better fit, oily skin needs ingredients like zinc pca and ceramides to control excess oil and pores without clogging.
What does Bifida Ferment Lysate do for oily skin?
Bifida Ferment Lysate helps keep oily skin calm and balanced by strengthening your skin barrier and defending against irritation. It also helps manage inflammation and provides antioxidant protection, making it a supportive choice for keeping skin clear and comfortable.
Journal of Cosmetic Dermatology, 2023Experimental Dermatology, 2010
What does Niacinamide do for oily skin?
Niacinamide helps balance oily skin by significantly reducing excess oil production and shine. It is well tolerated and may improve skin texture without clogging pores.
Journal of Cosmetic and Laser Therapy, 2006Antioxidants, 2021
Where does this serum go in a skincare routine for oily skin?
This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Oily skin works best with products of this type that include ingredients to manage shine and excess oil.
Can I use this serum with retinol, and in what order?
You can use this treatment with retinol by applying the treatment first and following with your retinol. Because this product supports skin barrier strength, it may help calm the skin, though an oily skin routine also needs ingredients that directly target excess shine.
How often should I use this serum?
You can use this treatment in the evening as part of your routine. Oily skin works best with products that contain balancing ingredients like niacinamide and lightweight hydrators to keep shine under control.
Can this serum clog pores, cause breakouts or purging for oily skin?
This treatment is unlikely to clog pores or cause breakouts on oily skin because it has a safe formula with no harsh or prohibited ingredients. However, because it does not actively manage oily shine, oily skin often needs lightweight hydrators and oil-controlling ingredients like niacinamide and salicylic acid to stay clear and balanced.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro.
Journal of Cosmetic Dermatology, 2023Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical treatment with pumpkin seed oil-loaded niosomes decreased fallen hairs by 44.42% and increased the anagen to telogen ratio by 1.4-fold after 8 weeks compared to initial conditions.
Pharmaceuticals, 2022Topical application of prickly pear, pumpkin, and linseed oils significantly reduced clinical signs of acute inflammation, inflammatory markers, and oxidative stress in carrageenan-treated rats compared to the normal saline-treated group.
BioMed Research International, 2020Enzyme-modified ginseng extract cream significantly reduced the global photo-damage score and various roughness measures including total roughness, smoothness depth, and arithmetic roughness average compared to placebo in 23 human subjects.
Rejuvenation Research, 2015A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects.
Journal of Ginseng Research, 2022A 1% fermented black ginseng cream significantly reduced eye wrinkles and brightened skin color in twenty-three human subjects compared to control cream and baseline.
Journal of Toxicology and Environmental Health. Part A, 2020Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019
Why other serums fit oily skin better
A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.
Journal of Cosmetic Dermatology, 2024Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo.
BioMed Research International, 2022
Ingredients
Bifida Lysate Ferment, Lactobacillus Pumpkin Fruit Ferment Filtrate, Niacinamide, Butylene Glycol, Acetyl Hexapeptide-8, Aureobasidium Pullulans Ferment, Hydrolyzed Algin, Caffeine, Panax Ginseng Root Extract, Panax Ginseng Callus Culture Extract, Glycerin, Epigallocatechin Gallate, Zanthoxylum Piperitum Fruit Extract, Pulsatilla Koreana Extract, Usnea Barbata Extract, Copper Tripeptide-1, Physalis Alkekengi Fruit Extract, Methyl Gluceth-20, Sodium Hyaluronate, Adenosine
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
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Specialist dermatologist, MBBS, MD, IFAAD
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Dermatology MD
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Elina Nazarenko, MD
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Dermatology and diagnostic consultant
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Victoria Derkova, MS
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Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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