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HydroPeptide Power Serum for sensitive skin

HydroPeptide Power Serum
  • Palmitoyl Tripeptide-5
  • Hexapeptide-11
  • Acetyl Hexapeptide-30
  • Sodium Hyaluronate
  • Lemon Peel Extract

High

  • HighNormal Skin Fit
  • AverageEffectiveness
  • ExcellentSafety

A great choice for sensitive skin; a few serums fit it even better.

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • This serum is highly suitable for your normal skin, as Glycerin and Sodium Hyaluronate provide essential hydration without overwhelming it, while Hexapeptide-11 and Tetrahexyldecyl Ascorbate work to smooth texture and brighten your skin tone.
  • The formula also offers supportive benefits for your redness and irritation by providing general hydration and soothing effects.
  • It is safe for your sensitive skin due to the absence of harsh ingredients and the inclusion of soothing components like Oat Protein and Tocopherol.

How to apply

  • Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
  • Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
  • Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
  • Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
  • Always do a patch test before your first use and avoid getting the serum too close to your eyes .

People Say

★4.8Overall rating based on 400+ reviews

Users consistently praise this serum as a lightweight, non-greasy anti-aging powerhouse that visibly plumps and smooths the skin. While it is highly effective for hydrating dry skin and softening fine lines without irritating sensitive complexions, the high price point and distinct scent are occasional points of contention.

Highlights

  • Lightweight texture Mostly Mentioned
    • “sinks right into skin”
    • “featherlight formula”
    • “perfect under makeup”
    • “no greasy residue”
  • Deep hydration Often Mentioned
    • “skin feels incredibly soft”
    • “visibly plumps”
    • “deeply hydrates without heaviness”
    • “glowing complexion”
  • Visible anti-aging Often Mentioned
    • “fine lines look reduced”
    • “skin feels firmer”
    • “years-younger appearance”
    • “unbelievable difference in 2 weeks”
  • High price point Often Mentioned
    • “a little pricey”
    • “worth the occasional splurge”
    • “wallet hurting”
    • “$154 is steep”
  • Gentle on skin Sometimes Noted
    • “doesn't irritate my sensitive skin”
    • “calming peptides”
    • “no redness or breakouts”
    • “gentle formula”
  • Pleasant scent Sometimes Noted
    • “smells like heaven”
    • “hint of grapefruit”
    • “light and refreshing”
    • “smells like cucumbers”
  • Packaging size Rarely Noted
    • “1oz is too small”
    • “wish it was bigger”
    • “pump stopped working”
    • “expensive for the size”
  • Scent dislike Rarely Noted
    • “smell is a little off-putting”
    • “can't stand the scent”
    • “smells terrible”
    • “fragrance isn't for everyone”
  • Slow results Rarely Noted
    • “didn't see dramatic results”
    • “no huge difference”
    • “takes consistent use”
    • “wrinkles still there”

Sources: lovi.care, hydropeptide.com, dermstore.com, lovelyskin.com, youtube.com, wimj.com, and more

Questions and answers

What makes HydroPeptide Power Serum a great fit for sensitive skin?

HydroPeptide Power Serum is a great fit for sensitive skin because it is free of harsh ingredients and includes calming components like oat protein and vitamin E. Glycerin and sodium hyaluronate help provide essential hydration, while peptides and vitamin C work to smooth texture and brighten your skin tone.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this serum a good fit for sensitive skin?

This serum is a great fit for sensitive skin because it avoids harsh ingredients and includes soothing components like Oat Protein and Tocopherol. These ingredients help keep skin calm while reducing redness and irritation.

What does Palmitoyl Tripeptide-5 do for sensitive skin?

Palmitoyl Tripeptide-5 helps smooth fine lines and keeps skin looking firm and youthful. It is unlikely to irritate sensitive skin, but a product for this skin type also needs soothing ingredients to keep it calm and comfortable.

Colloids and Surfaces. B, Biointerfaces, 2025

What does Hexapeptide-11 do for sensitive skin?

Hexapeptide-11 helps protect sensitive skin against everyday stress and may improve firmness. Sensitive skin needs gentle ingredients that calm irritation and strengthen its natural barrier, such as soothing plant extracts and barrier-repairing lipids.

Redox Biology, 2015

Where does this serum go in a skincare routine for sensitive skin?

This serum goes in your evening routine, applied after your soothing toner and before your moisturizer. Putting treatments in the evening provides extra safety around sun exposure, and this formula is gentle enough for your skin because it lacks harsh ingredients and includes soothing components.

Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying your retinol product first and following with this serum to keep your skin calm and hydrated. This formula is safe for sensitive skin due to the lack of harsh ingredients and the presence of soothing components like oat protein and tocopherol.

Journal of Cosmetic Dermatology, 2024

How often should I use this serum?

You can use this treatment in the evening as part of your routine, or sometimes in the morning or twice a day if your skin likes it. It is safe for sensitive skin due to the absence of harsh ingredients and the inclusion of soothing components like oat protein and tocopherol.

Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts for sensitive skin because it is free of harsh, heavy ingredients and relies on lightweight hydration. It helps keep your skin calm and balanced without triggering irritation.

Clinical, Cosmetic and Investigational Dermatology, 2017

Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017
  • A 3-in-1 anti-aging topical night serum-in-oil applied once daily decreased wrinkles by 11%, increased skin firmness by 8%, reduced redness by 70%, and improved overall skin quality and complexion in 103 female subjects over 28 to 84 days compared to baseline.

    Journal of Cosmetic Dermatology, 2019
  • Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects.

    Colloids and Surfaces. B, Biointerfaces, 2025
  • Hexapeptide-11 activated proteasome, autophagy, chaperones, and antioxidant response genes, protected fibroblasts against oxidative-stress-mediated premature cellular senescence, and improved skin elasticity in human subjects.

    Redox Biology, 2015
  • Hexapeptide-11 reversibly downregulated ATM and p53 protein expression in intrinsically aged fibroblasts, extrinsically aged fibroblasts, and extrinsically aged dermal papillae cells at concentrations between 0.1% and 1.0% in vitro, thereby influencing the onset of cellular senescence.

    Journal of Cosmetic Science, 2013
  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011
  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022
  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019

Ingredients

Water, Glycerin, Lactococcus Lysate Ferment, Butylene Glycol, Propanediol, Diethylhexyl Carbonate, Isopentyldiol, Pentylene Glycol, Diheptyl Succinate, Caprylyl Glycol, Hydroxyacetophenone, Olea Europaea Fruit Olive Fruit, Sodium Stearoyl Glutamate, Cetearyl Alcohol, Glyceryl Stearate, Potassium Olivoyl Hydrolyzed Oat Protein, Lysolecithin, Sclerotium Gum, Hexapeptide-11, Tetrahexyldecyl Ascorbate, 1,2-Hexanediol, Capryloyl Glycerin Sebacic Acid Copolymer, Phenylpropanol, Sorbitan Laurate, Pullulan, Xanthan Gum, Caprylic Capric Triglyceride, Glyceryl Oleate, Glycine Soja Seed Extract Soybean Seed Extract, Anogeissus Leiocarpus Bark Extract, Lemon Peel Extract, Palmitoyl Hexapeptide-19, Sodium Phytate, Hydroxyethylcellulose, Sodium Hyaluronate, Acetyl Dipeptide-1 Cetyl Ester, Citrus Aurantium Dulcis Peel Extract, Grapefruit Fruit Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Bergamot Fruit Extract, Citrus Aurantifolia Peel Extract, Citrus Nobilis Fruit Extract Mandarin Orange Fruit Extract, Tangerine Peel Extract, Acetyl Hexapeptide-30, Barosma Betulina Leaf Extract, Vanilla Planifolia Fruit Extract, Vitis Vinifera Fruit Extract Grape Fruit Extract, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-5, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Tocopherol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

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Prices checked 5 Nov 2026

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.