Dear, Klairs Midnight Blue Youth Activating Drop for dry skin
Rh-Oligopeptide-1
Sh-Polypeptide-1
Blueberry Fruit Extract
GuaiazuleneHigh
- HighDry Skin Fit
- HighEffectiveness
- ExcellentSafety
A great choice for dry skin; a few serums fit it even better.
- Clinical, Cosmetic and Investigational Dermatology, 2017
- Clinical, Cosmetic and Investigational Dermatology, 2020
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent skin rejuvenation for your dry skin due to Sh-Oligopeptide-1 and Sh-Polypeptide-1, which minimize fine lines and wrinkles while glycerin and blueberry fruit extract provide essential hydration and antioxidant support.
- The presence of Guaiazulene further enhances its suitability by offering soothing benefits, complementing the product's overall hydrating and anti-aging functions.
- The safety profile is excellent, with no risks of irritation for your dry skin due to the absence of harsh ingredients and the inclusion of soothing components.
How to apply
- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
People Say
★4.4Overall rating based on 1.5k+ reviewsBased on a very large amount of data, this product is widely praised as a lightweight, watery anti-aging serum that absorbs instantly and is exceptionally gentle, making it a favorite for oily and sensitive skin types. Many users report smoother skin texture, reduced redness, and a plump feel. Some find the 20ml bottle too small for the price and note that its preventative anti-aging effects take time to become visible.
Highlights
Rapid absorption Mostly Mentioned
- “absorbs like a dream”
- “drinks it up instantly”
- “leaves no residue”
- “disappears into skin”
Small volume/price Mostly Mentioned
- “finished in 3 weeks”
- “wish it was bigger”
- “pricey for the size”
- “tiny bottle”
Gentle formula Often Mentioned
- “didn't break me out”
- “no stinging”
- “safe for reactive skin”
Soothing & calming Often Mentioned
- “calms my redness”
- “soothing on sensitive skin”
- “helps with irritation”
- “great for post-sun”
Improves texture Sometimes Noted
- “skin feels softer”
- “noticed smoother texture”
- “woke up glowing”
- “pores look smaller”
Slow visible results Sometimes Noted
- “didn't see wrinkle reduction”
- “takes months to work”
- “more preventative than corrective”
- “no dramatic difference”
Watery consistency Sometimes Noted
- “runs off my hand”
- “hard to control dropper”
- “too thin like water”
- “spills easily”
Not moisturizing Rarely Noted
- “need moisturizer on top”
- “feels like just water”
- “not enough hydration”
- “must layer quickly”
Sources: lovi.care, iherb.com, sokoglam.com, wishtrend.com, yesstyle.com, reddit.com, and more
Questions and answers
What makes the Midnight Blue Youth Activating Drop a great fit for dry skin?
This treatment is a great fit because it helps smooth fine lines and wrinkles while giving your dry skin essential hydration and antioxidant support. It also calms your skin safely without any harsh ingredients that could cause irritation.
Clinical, Cosmetic and Investigational Dermatology, 2017Clinical, Cosmetic and Investigational Dermatology, 2020
Which ingredients make this serum a good fit for dry skin?
Sh-Oligopeptide-1 and sh-polypeptide-1 make this serum a great fit for your dry skin by smoothing out fine lines, while glycerin and blueberry fruit extract give your skin essential moisture and antioxidant support. Guaiazulene also helps by calming the skin.
What does EGF do for dry skin?
EGF helps improve dry skin by supporting the skin barrier and keeping the skin soft and smooth. Studies show it may reduce water loss and boost hydration.
Where does this serum go in a skincare routine for dry skin?
This serum goes in your evening routine after cleansing and before your moisturizer. Using it at night helps keep things simple and safe around sun exposure while peptides and blueberry fruit extract deliver hydration and rejuvenation.
Can I use this serum with retinol, and in what order?
You can use this treatment alongside retinol by applying the serum first at night before your moisturizer. This routine helps deliver anti-aging benefits while keeping your skin calm and hydrated, and it is unlikely to cause irritation.
How often should I use this serum?
You can use this treatment in your evening routine, and some treatments can also be used in the morning or twice a day. It helps smooth fine lines while offering essential hydration and soothing benefits for dry skin with a very low risk of irritation.
Can this serum clog pores, cause breakouts or purging for dry skin?
This serum is unlikely to clog pores, cause breakouts, or lead to purging for dry skin. It has a very safe formula with soothing ingredients and no harsh components that typically cause irritation or breakouts.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017A 0.4% formulation of natural pterostilbene reduced markers of aging, wrinkles, and fine lines while improving skin hydration and elasticity in healthy volunteers over 8 weeks.
Clinical, Cosmetic and Investigational Dermatology, 2020Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone.
The New England Journal of Medicine, 1989Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba.
Lasers in Surgery and Medicine, 2020Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars.
The Journal of Clinical and Aesthetic Dermatology, 2022Topical application of PTD-EGF and FGF1 increased cell proliferation and collagen accumulation while protecting against UV-induced damage and improving wrinkle parameters in human skin.
Journal of Cosmetic Dermatology, 2013Basic fibroblast growth factor-loaded human serum albumin nanoparticles enhanced the proliferation and migration of human dermal fibroblasts, down-regulated myofibroblast-related genes, and accelerated wound healing with enhanced angiogenesis in vivo compared to unstable native forms.
Journal of Nanobiotechnology, 2023Topical application of basic fibroblast growth factor decreases elevated transepidermal water loss and increases Ki67 expression in keratinocytes following mechanical scratching in a mouse model.
Skin Pharmacology and Physiology, 2013Applying a topical product containing blueberry extract and Pro-xylane following micro-focused ultrasound significantly improved global aesthetic improvement, skin elasticity, and fine lines compared to standard moisturizer in 50 patients.
Journal of Cosmetic Dermatology, 2025Topical usage of blueberries may prevent skin damage from environmental stressors by inducing an active skin response against noxious effects.
Antioxidants, 2023Pretreatment with blueberry extracts prevented ozone-induced ROS production, NLRP1-ASC scaffold formation, and CASP1 and IL-18 transcripts across 2D, 3D, and human skin explant models.
Oxidative Medicine and Cellular Longevity, 2020
Ingredients
Water, Butylene Glycol, Sh-Oligopeptide-1, Sh-Polypeptide-1, Blueberry Fruit Extract, Lecithin, Sorbitan Sesquioleate, 1,2-Hexanediol, Caprylyl Glycol, Peg-60 Hydrogenated Castor Oil, Glycerin, Chlorphenesin, Guaiazulene, Ethylhexylglycerin, Adenosine
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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