Theramid DERMA-PEPTIDES for sensitive skin
Palmitoyl Tripeptide-1
Sh-Oligopeptide-1
Palmitoyl Tetrapeptide-7
Average
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
Works for sensitive skin; other moisturizers fit it better.
- International Journal of Cosmetic Science, 2024
- Clinical, Cosmetic and Investigational Dermatology, 2017
This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers supportive benefits for redness and irritation due to the presence of Palmitoyl Tripeptide-1 and Sh-Oligopeptide-1, which promote skin barrier repair, making it suitable for your normal skin type. Glycerin and propanediol provide moderate hydration, supporting overall skin comfort.
- The formulation is safe for your sensitive skin, as it lacks any harsh or prohibited ingredients that could cause irritation.
- This product is generally safe for your sensitive skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
People Say
★4.7Overall rating based on 300+ reviewsUsers frequently praise this serum for its lightweight, non-sticky texture and its effectiveness in delivering visible anti-aging results, such as increased skin plumpness and reduced fine lines. It is also noted for its gentle, fragrance-free formulation, making it suitable for sensitive skin and compatible with other active ingredients.
Highlights
Visible anti-aging Mostly Mentioned
- “Fine lines are less visible”
- “Skin looks plumper”
- “More youthful skin”
Gentle formulation Often Mentioned
- “Suitable for sensitive skin”
- “No strong scent”
- “No sensitising occurring”
Lightweight texture Often Mentioned
- “Absorbs quickly”
- “Doesn't leave stickiness”
- “Lotion-like texture”
Good value Sometimes Noted
- “Price is unbeatable”
- “Affordable serums”
- “Quality for price”
Practical packaging Sometimes Noted
- “Love the pump”
- “Pipettes are annoying”
- “Packaging pleases senses”
High expectations Rarely Noted
- “Overhyped by influencers”
- “Waiting for results”
- “Not a miracle”
Limited availability Rarely Noted
- “Hard to find in stores”
- “Only online”
- “Shipping delays”
Packaging preference Rarely Noted
- “Prefer glass bottles”
- “Pump can clog”
- “Hard to see level”
Sources: lovi.care, nichebeautylab.com, skintskincare.com, reddit.com, youtube.com, and more
Questions and answers
How well does Theramid Derma-Peptides work for sensitive skin?
Theramid Derma-Peptides works fine for sensitive skin, though other products fit it better because they provide deeper hydration and stronger soothing care. This product needs richer hydrating ingredients and calming extracts to keep this skin soft, smooth, and comfortable.
Which ingredients make this treatment a good fit for sensitive skin?
Palmitoyl Tripeptide-1, Sh-Oligopeptide-1, and Palmitoyl Tetrapeptide-7 make this treatment a fit by offering supportive benefits for redness and irritation while helping repair the skin barrier. Glycerin and propanediol also provide moderate hydration to support overall skin comfort without harsh ingredients. A moisturizing treatment for this skin needs rich hydrating ingredients and soothing agents that enhance hydration and maintain the skin barrier without causing irritation.
What does Palmitoyl Tripeptide-1 do for sensitive skin?
Palmitoyl tripeptide-1 helps smooth fine lines and improves firmness in sensitive skin. It works by supporting collagen levels to keep skin looking youthful and resilient.
Journal of Cosmetic Dermatology, 2026International Journal of Cosmetic Science, 2026
What does EGF do for sensitive skin?
EGF helps calm sensitive skin by supporting barrier recovery and reducing moisture loss after irritation. It also helps protect skin cells from environmental damage and lowers inflammation to keep your face feeling soft and smooth.
Where does this treatment go in a skincare routine for sensitive skin?
This treatment goes in the evening routine after cleansing and a soothing toner, followed by a moisturizer. A product for this skin type needs barrier-repairing peptides and gentle, hydrating ingredients to keep the skin calm and comfortable.
Can I use this treatment with retinol, and in what order?
You can use this treatment with retinol, applying it after your retinol step to help calm and comfort your skin. A product of this type for sensitive skin needs soothing ingredients like ceramides and centella asiatica to further reduce redness and strengthen the skin barrier.
How often should I use this treatment?
Apply this treatment in the evening as part of your PM routine, as the formulation is safe for your sensitive skin and lacks harsh ingredients. For this skin type, a product of this type needs barrier-repairing ingredients like Palmitoyl Tripeptide-1 and Sh-Oligopeptide-1 along with moderate hydrators like glycerin and propanediol to help calm redness and irritation.
Can this treatment clog pores, cause breakouts or purging for sensitive skin?
This treatment is unlikely to clog pores or cause breakouts on sensitive skin, as it lacks harsh ingredients and relies on gentle hydrators like glycerin. However, because other products may suit sensitive skin better, this type of treatment works best when it includes soothing ingredients and barrier-repairing peptides to keep skin calm and smooth.
Can I use this treatment around the eyes or on my body?
This treatment is safe to use around the eyes and on the body because it lacks harsh ingredients, though sensitive skin requires products with barrier-repairing peptides and moderate hydration for the best fit.
What the research says
Topical application of 1,3-propanediol at various concentrations, alone or combined with butylene glycol and/or glycerol, increased skin hydration and reduced trans epidermal water loss in 30 healthy female subjects over an 8-hour period, with the 15% concentration and the addition of glycerol providing greater benefits.
International Journal of Cosmetic Science, 2024A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.
Journal of Cosmetic Dermatology, 2015Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.
Journal of Cosmetic Dermatology, 2026Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.
International Journal of Cosmetic Science, 2026Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone.
The New England Journal of Medicine, 1989Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba.
Lasers in Surgery and Medicine, 2020Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars.
The Journal of Clinical and Aesthetic Dermatology, 2022
Ingredients
Water, Glycerin, Propanediol, Caprylic Capric Triglyceride, Palmitoyl Tripeptide-1, Sh-Oligopeptide-1, Palmitoyl Tetrapeptide-7
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
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Specialist dermatologist, MBBS, MD, IFAAD
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Dermatology MD
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Elina Nazarenko, MD
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Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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