🇳🇱Netherlands

Lancôme Génifique Ultimate for oily acne-prone skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Lancôme Génifique Ultimate

Average

  • HighOily Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for oily acne-prone skin; other serums fit it better.

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate hydration and skin barrier resilience for your oily skin, as bifida ferment lysate and hyaluronic acid support moisture retention without adding excess oil. Glycerin further enhances this humectant action, making it suitable for your skin type.
  • While beneficial for general skin health, the formula does not specifically target your concerns of acne, blemishes, and breakouts.
  • The product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients.

How to apply

  • Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
  • Apply your serum after cleansing and toning, but before putting on your moisturizer.
  • Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
  • Apply the serum on clean, dry skin to help manage your blemishes safely.
  • Do a patch test before your first use and avoid the delicate eye area.

People Say

★4.6Overall rating based on 1.2k+ reviews

Based on a very large amount of data, users love this serum's lightweight, silky texture that absorbs quickly, leaving skin feeling soothed, hydrated, and plump without any stickiness. While many experience smoother skin and a strengthened barrier, some note that anti-aging effects like wrinkle reduction are subtle and require consistent, long-term use. The high price point is frequently mentioned as a drawback.

Highlights

  • Lightweight texture Mostly Mentioned
    • “absorbs almost instantly”
    • “lightweight and silky”
    • “no sticky residue”
    • “glides effortlessly”
  • Hydration and plumping Often Mentioned
    • “skin felt more plump”
    • “luxuriously hydrating”
    • “healthy luminous glow”
    • “dewy and fresh”
  • Soothing and calming Often Mentioned
    • “instantly soothed my skin”
    • “redness has decreased”
    • “calming on contact”
    • “great for sensitive skin”
  • High price point Often Mentioned
    • “bit of a splurge”
    • “price is steep”
    • “hard to justify cost”
    • “expensive for the amount”
  • Improves skin texture Sometimes Noted
    • “pores looked more refined”
    • “baby-soft skin”
    • “texture looked refined”
    • “smoother feeling skin”
  • Makeup compatibility Sometimes Noted
    • “layers beautifully under makeup”
    • “helps makeup apply better”
    • “works well under foundation”
  • Subtle results Sometimes Noted
    • “didn't notice much change in wrinkles”
    • “results feel subtle”
    • “needs consistent use”
    • “not an overnight fix”
  • Dropper design Rarely Noted
    • “struggled to open cap”
    • “dropper is finicky”
    • “hard to get last drops”
  • Pilling issues Rarely Noted
    • “pilling like dead skin”
    • “pills if not fully absorbed”
    • “rubbed off when layering”
  • Unpleasant scent Rarely Noted
    • “can't get used to the smell”
    • “distinctive fermented scent”
    • “smell is a bit unusual”

Sources: lovi.care, sephora.com.au, hometesterclub.com, ult.com, beautycrew.com.au, dailyvanity.sg, and more

Questions and answers

How well does Lancôme Génifique Ultimate work for oily acne-prone skin?

Lancôme Génifique Ultimate works reasonably well for oily acne-prone skin by offering moderate moisture and supporting your skin barrier without adding extra oil, though it does not target breakouts specifically. To better fit this skin type, a treatment needs ingredients like niacinamide, propolis, or Vitamin C to help control excess oil and address blemishes.

Clinical, Cosmetic and Investigational Dermatology, 2017Contemporary Clinical Trials Communications, 2021

Which ingredients make this serum a good fit for oily acne-prone skin?

Bifida lysate ferment, hyaluronic acid, and glycerin make this serum a good fit for your oily skin by adding moisture without extra oil. To work best for oily acne-prone skin, this type of product also needs ingredients like niacinamide, propolis, or vitamin C to clear breakouts and control excess oil.

Clinical, Cosmetic and Investigational Dermatology, 2017

What does Bifida Ferment Lysate do for oily acne-prone skin?

Bifida Ferment Lysate helps calm oily acne-prone skin by strengthening your skin barrier and lowering irritation. It is unlikely to clog pores and may help keep your skin feeling smooth and balanced.

Journal of Cosmetic Dermatology, 2023Experimental Dermatology, 2010

What does Hyaluronic Acid do for oily acne-prone skin?

Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.

The Journal of Investigative Dermatology, 2017Journal of Cosmetic Dermatology, 2022

Where does it go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Oily acne-prone skin needs a product that also targets breakouts and blemishes with ingredients like salicylic acid or benzoyl peroxide.

Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol, applying the treatment after your retinol to keep your skin soft and hydrated without adding extra oil. This product is safe for your skin and unlikely to cause irritation.

Clinical, Cosmetic and Investigational Dermatology, 2017Contemporary Clinical Trials Communications, 2021

How often should I use it?

You can use this treatment in your evening routine. A product for oily acne-prone skin needs ingredients that target breakouts and blemishes while keeping the skin clear.

Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to clog pores or cause breakouts because it is free of harsh ingredients and heavy oils, but it also does not actively treat acne. Oily acne-prone skin needs a product of this type that contains targeted blemish-fighting ingredients and oil-balancing agents.

Contemporary Clinical Trials Communications, 2021Journal of Cosmetic Dermatology, 2023

Is it fragrance-free and alcohol-free?

It contains fragrance (parfum) and drying alcohol (alcohol denat).

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017

  • Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro.

    Journal of Cosmetic Dermatology, 2023

  • Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.

    Contemporary Clinical Trials Communications, 2021

  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011

  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022

  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019

  • The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

    Journal of Cosmetic Dermatology, 2020

  • Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

    International Journal of Cosmetic Science, 2001

  • Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

    Journal of Drugs in Dermatology, 2012

  • Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.

    Journal of Cosmetic Dermatology, 2025

  • Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.

    Journal of Cosmetic Dermatology, 2024

  • A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use.

    Journal of Cosmetic Dermatology, 2022

  • Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months.

    The Journal of Dermatology, 2008

  • Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants.

    International Journal of Molecular Sciences, 2026

  • Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts.

    International Journal of Molecular Sciences, 2021

Why other serums fit oily acne-prone skin better

Ingredients

Water, Bifida Lysate Ferment, Glycerin, Dimethicone, Alcohol Denat, Hydroxyethylpiperazine Ethane Sulfonic Acid, Hyaluronic Acid, Tocopheryl Acetate, Adenosine, Phenoxyethanol, Ammonium Polyacryloyldimethyl Taurate, Sodium Hydroxide, Caprylyl Glycol, Disodium Edta, Citric Acid, Xanthan Gum, Polysorbate 20, Parfum

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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Prices checked 10 Oct – 17 Oct 2026

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.

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