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Azclear Medicated Lotion for combination skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Azclear Medicated Lotion

Average

  • HighCombination Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for combination skin; other serums fit it better.

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate treatment for your acne-prone combination skin, as azelaic acid helps reduce acne lesions and blemishes while glycerin provides hydration.
  • Aluminum and magnesium silicate offer mattifying effects that can help with oily shine, though stronger mattifying agents might be more effective for your primary concern.
  • The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

How to apply

  • Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
  • Apply the serum after cleansing and toner, and right before your moisturizer.
  • Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
  • Apply the serum on clean and dry skin since your skin is not sensitive.
  • Always do a patch test before using the serum for the first time, and avoid the eye area .

People Say

★4.5Overall rating based on 400+ reviews

A common drawback is the product's tendency to pill or ball up when layered with other products.

Highlights

  • Effective acne treatment Mostly Mentioned
    • “clears stubborn acne”
    • “hormonal breakouts substantially smaller”
    • “fixes hormonal acne and oiliness”
  • Pilling and texture Mostly Mentioned
    • “formula does pill a bit”
    • “finicky formula that pills easily”
    • “hard to put sunscreen over it”
  • Reduces redness Often Mentioned
    • “far less red”
    • “calmed my breakout without scarring”
  • Affordable value Sometimes Noted
    • “amazing affordable treatment”
    • “great value”
    • “cheap and effective”
  • Gentle and non-drying Sometimes Noted
    • “doesn't dry my skin out”
    • “less harsh than other treatments”
    • “hydrating but not greasy”
  • Stinging sensation Sometimes Noted
    • “stung so bad”
    • “skin was a little itchy”
    • “tingling for an hour”
  • Slow absorption Rarely Noted
    • “waiting for it to dry completely”
    • “hard to layer”
    • “leaves a white cast if not rubbed in”

Sources: lovi.care, chemistwarehouse.com.au, chemistdirect.com.au, skinsort.com, sayso.com.au, reddit.com, and more

Questions and answers

How well does Azclear Medicated Lotion work for combination skin?

Azclear Medicated Lotion works moderately well for combination skin by helping clear acne spots with azelaic acid, hydrating with glycerin, and reducing oily shine with aluminum and magnesium silicate. It is safe for this skin type, but this skin needs ingredients like niacinamide, zinc PCA, and propolis to balance moisture and regulate oiliness more effectively.

Pharmaceutics, 2021Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this lotion a good fit for combination skin?

Azelaic acid helps reduce blemishes and glycerin provides hydration for your combination skin. A treatment for combination skin needs effective ingredients like niacinamide, propolis, and zinc PCA to enhance radiance and regulate oiliness without irritation.

Pharmaceutics, 2021Dermatology and Therapy, 2024

What does Azelaic Acid do for combination skin?

Azelaic acid helps calm angry, red spots and smooth out rough or uneven patches on combination skin. It also helps clear pores and keeps skin looking even without causing extra dryness.

Postepy Dermatologii I Alergologii, 2023Journal of Drugs in Dermatology, 2015

What does Glycerin do for combination skin?

Glycerin helps keep combination skin soft and smooth by pulling moisture in and keeping it there. It improves hydration and supports your skin barrier, which is unlikely to cause irritation.

The British Journal of Dermatology, 2008Clinical, Cosmetic and Investigational Dermatology, 2017

Where does this lotion go in a skincare routine for combination skin?

This treatment goes in your evening routine, applied after cleansing and before moisturizing. It is safe for your combination skin and helps reduce blemishes, though combination skin also needs stronger mattifying agents to fully control oily shine.

Can I use it with retinol, and in what order?

You can use this treatment alongside retinol by applying the retinol first at night and following with this lotion, though your combination skin needs a product with stronger mattifying ingredients to best handle oily shine.

How often should I use this lotion?

Use this lotion in the evening routine. A product of this type needs stronger mattifying agents to best care for combination skin.

Can it clog pores, cause breakouts or purging for combination skin?

This treatment is unlikely to clog pores or cause breakouts on your combination skin because it contains acne-fighting azelaic acid and hydrating glycerin. It is safe for your skin type with no risk of irritation from harsh ingredients, though a product for this skin needs stronger mattifying agents to better handle oily shine.

Pharmaceutics, 2021Clinical, Cosmetic and Investigational Dermatology, 2017

Is this lotion fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne.

    Pharmaceutics, 2021

  • Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo.

    Dermatology and Therapy, 2024

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017

  • Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks.

    Journal of the European Academy of Dermatology and Venereology, 2023

  • Topical administration of 20% azelaic acid cream and 5% tranexamic acid solution comparably improved acne-related postinflammatory hyperpigmentation in patients with acne vulgaris, while tranexamic acid demonstrated a significantly better safety profile at week 4.

    Journal of Research in Medical Sciences, 2023

  • Azelaic acid 15% gel showed comparable efficacy to adapalene 0.1% gel in reducing lesions, severity, and Dermatology Life Quality Index in women with adult acne, with significantly lower dryness and scaling, and demonstrated superiority during maintenance compared to no further treatment.

    Journal of the European Academy of Dermatology and Venereology, 2015

  • The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

    Journal of Cosmetic Dermatology, 2020

  • Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

    International Journal of Cosmetic Science, 2001

  • Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

    Journal of Drugs in Dermatology, 2012

  • Biodegradable wound dressings functionalized with silver nanoparticles showed >99% pathogen growth inhibition, bactericidal effects, free radical scavenging, reduced inflammatory response in macrophages, and accelerated wound healing in animals.

    International Journal of Biological Macromolecules, 2022

  • A topical xanthan gum nanogel containing gamma-oryzanol-loaded nanostructured lipid carriers and nanosized TiO2 and MBBT filters demonstrated high photoprotection with an SPF of 34 and no skin irritation or sensitization in a rat model.

    Pharmaceuticals, 2023

  • Dense chitosan-xanthan membranes associated with multipotent mesenchymal stromal cells accelerated wound healing in Wistar rats compared to untreated conditions, demonstrating safety and feasibility for dermo-epidermal wound treatment.

    Journal of Biomaterials Applications, 2015

Why other serums fit combination skin better

  • Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo.

    BioMed Research International, 2022

  • A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.

    Journal of Cosmetic Dermatology, 2024

Ingredients

Azelaic Acid, Aluminum, Magnesium Silicate, Colloidal Silicon Dioxide, Glycerin, Phenoxyethanol, Water, Xanthan Gum

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.

QR code: get the Lovi app
Download on theApp Store Get it onGoogle Play