SK-II and Galderma are skincare brands founded in Japan in 1980 and Switzerland in 1981, respectively. SK-II offers moisturizers, nourishing serums , rejuvenating masks, and refreshing toners anchored by pitera, while Galderma focuses on specialized serums. Both brands suit acne-prone skin, dry skin, skin with dark spots, and mature skin. The Japanese brand differs by relying on time-tested ingredients to improve pore area, skin roughness, and redness, whereas the Swiss brand features targeted treatments like Epiduo Gel and Benzac AC.
SK-II is a Japanese skincare brand founded in 1980 and owned by The Procter & Gamble Company since 1991.
en.wikipedia.org discoversk-ii.wixsite.com glossy.co
Galderma is a Swiss skincare brand founded in 1981 and owned by Galderma Group AG.
en.wikipedia.org
This page compares some of the most popular SK-II and Galderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app .
Popular SK-II vs Galderma products
People Say
SK-II Galderma
+ Clears acne and prevents breakouts
Not noted Mostly Mentioned
“cleared up my skin — Galderma Benzac AC Mild Strength 2.5% Acne Gel” “cystic acne gone — Galderma Epiduo Gel” “stops new pimples — Galderma Epiduo Gel”
+ Improves texture and smoothness
Mostly Mentioned Sometimes Noted
“skin feels soft as butter — SK-II Facial Treatment Essence” “pores became miraculously invisible — SK-II Facial Treatment Mask” “Smoother skin — SK-II Facial Treatment Clear Lotion” “skin feels smooth — Galderma Epiduo Gel”
+ Radiance and glow
Mostly Mentioned Not noted
“gives a glass skin look — SK-II Facial Treatment Essence” “leaves me with a red carpet glow — SK-II Facial Treatment Mask” “My skin is glowing now. — SK-II Genoptics Ultraura Essence”
+ Deep hydration and moisture
Mostly Mentioned Not noted
“flooded my skin with moisture — SK-II Facial Treatment Mask” “skin feels deeply hydrated, plump, and smoother — SK-II Skinpower Advanced Cream” “Leaves skin soft, feels moisturized, does not dry out skin. — SK-II Facial Treatment Cleansing Oil”
+ Lightweight and absorbent
Often Mentioned Not noted
“drinks right into the skin — SK-II Facial Treatment Essence” “Absorbs into the skin quickly. — SK-II Genoptics Ultraura Essence” “Absorbs quickly — SK-II Genoptics Spot Essence”
+ Anti-aging and brightening
Often Mentioned Not noted
“Skin looks brighter — SK-II Genoptics Spot Essence” “Reduced sun spots — SK-II Genoptics Spot Essence” “reducing the appearance of fine lines — SK-II Skinpower Advanced Cream”
– Intense burning and severe dryness
Not noted Mostly Mentioned
“face on fire — Galderma Epiduo Gel”
– High price
Mostly Mentioned Not noted
“way too expensive — SK-II Facial Treatment Essence”
– Breakouts and skin purging
Often Mentioned Mostly Mentioned
“caused tiny red bumps — SK-II Facial Treatment Essence” “dried to a tacky finish — SK-II Facial Treatment Mask” “Small bumps — SK-II Facial Treatment Clear Lotion” “got worse first — Galderma Epiduo Gel”
– Redness, irritation, and stinging
Not noted Mostly Mentioned
“red as tomato — Galderma Epiduo Gel”
– Bleaches fabrics
Not noted Mostly Mentioned
“bleached my towel — Galderma Benzac AC 5”
– Lack of results or underwhelming effect
Often Mentioned Not noted
“did absolutely nothing — SK-II Facial Treatment Essence”
Questions and answers
SK-II or Galderma: which is better?
What is the difference between SK-II and Galderma?
SK-II helps provide deep hydration and radiance with products on this page, whereas Galderma is more effective at clearing acne and preventing breakouts.
Which is more affordable, SK-II or Galderma?
Galderma is more affordable, whereas SK-II has a high price compared to Galderma.
Which causes fewer breakouts, SK-II or Galderma?
Which brand has products with fragrance, SK-II or Galderma?
Every product on the SK-II and Galderma pages lists no fragrance in its ingredients.
Which brand offers better results for radiance and glow, SK-II or Galderma?
SK-II offers better results for radiance and glow, as the products on this page help improve radiance and glow while Galderma lacks results in this area.
Where were SK-II and Galderma founded and when?
SK-II was founded in Japan in 1980, and Galderma was founded in Switzerland in 1981.
2 more questions
Research behind their key ingredients
31 more studies
The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study
Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy
Niacinamide · Journal of Cosmetic Dermatology, 2021 Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison
Adapalene · American Journal of Clinical Dermatology, 2018 Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure
Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of Shoulder and Elbow Surgery, 2021 Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug
Benzoyl peroxide, Benzoyl peroxide 25mg g · American Journal of Clinical Dermatology, 2022 A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population
Salicylic acid · BioMed Research International, 2020 A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora
Panthenol, D-pantothenyl alcohol · The Journal of Dermatological Treatment, 2017 Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging
Niacinamide · Scientific Reports, 2024 A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial
Adapalene · Archives of Dermatological Research, 2022 Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial
D-pantothenyl alcohol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020 Development of Multifunctional Cosmetic Cream Using Bioactive Materials from Streptomyces sp. T65 with Synthesized Mesoporous Silica Particles SBA-15
Silicon dioxide · Antioxidants, 2020 Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula
Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2021 Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study
Salicylic acid · Journal of Cosmetic Dermatology, 2024 Formulating octyl methoxycinnamate in hybrid lipid-silica nanoparticles: An innovative approach for UV skin protection
Silicon dioxide · Heliyon, 2020 A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide
Salicylic acid · Journal of Drugs in Dermatology, 2023 Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials
Adapalene · Journal of the American Academy of Dermatology, 2023 Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies
Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of the American Academy of Dermatology, 2023 Semi-Solid Dosage Forms Containing Pranoprofen-Loaded NLC as Topical Therapy for Local Inflammation: In Vitro, Ex Vivo and In Vivo Evaluation
Carbomer 940 · Gels, 2023 Reduction in the appearance of facial hyperpigmentation by topical N-undecyl-10-enoyl-L-phenylalanine and its combination with niacinamide
Undecylenoyl phenylalanine · Journal of Cosmetic Dermatology, 2009 Inhibitory effects of shell of Camellia oleifera Abel extract on mushroom tyrosinase and human skin melanin
Butylene glycol · Journal of Cosmetic Dermatology, 2019 A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines
Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010 Influence of vitamin E acetate on stratum corneum hydration
Tocopheryl acetate · Arzneimittel-Forschung, 1998 Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer
Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2022 Three clinical studies showing the anti-aging benefits of sodium salicylate in human skin
Sodium salicylate · Journal of Cosmetic Dermatology, 2010 Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study
Panthenol, D-pantothenyl alcohol · Journal of Cosmetic Dermatology, 2025 Glycerol crosslinked vitamin E loaded xanthan gum and gellan gum nanoemulgels for topical management of dry skin
Xanthan gum · International Journal of Biological Macromolecules, 2025 A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females
L-ascorbic acid 2-glucoside, Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016 Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study
Galactomyces ferment filtrate, Pitera essence, Pitera ferment filtrate galactomyces ferment filtrate, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate, Pitera · Journal of Clinical Medicine, 2023 Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
L-ascorbic acid 2-glucoside, Ascorbyl glucoside · International Journal of Molecular Sciences, 2024 The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color
Galactomyces ferment filtrate, Sk-ii pitera concentrate, Galactomyces ferment filtrate pitera ferment filtrate · Skinmed, 2021 Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial
Ascorbyl glucoside · Cureus, 2026
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Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
Nadia Kapleva, MS
Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
Alexey Shagraev, PhD
Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
Aishani Shah, MD
Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
Asya Zubkova, MS
Medical Board
Cosmetic chemist, SCS, IFSCC member
Hanna Kurets, MD
Medical Board, Medical Advisor
Dermatology MD
Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist