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Sesderma vs NIOD

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Sesderma and NIOD are advanced skincare brands known for their meticulously engineered and sophisticated serums. The Spanish brand, founded in 1989 and owned by Grupo Sesderma since 2026, features botanical extracts and active compounds that suit sensitive, hyperpigmented, and aging skin types, with standout products like the Azelac RU Serum for acne-prone skin. Meanwhile, the Canadian brand, founded in 2015 and owned by The Estée Lauder Companies Inc. since 2021, delivers targeted results through balancing toners and thoughtful development that suit mature, sensitive, and dry skin types, featuring standout items such as Modulating Glucosides for acne-prone skin and Superoxide Dismutase Saccharide Mist for skin with dark spots. Both lines differ primarily in their formulation philosophies, as the former relies on synergistic botanical blends to refine texture and promote radiance, while the latter redefines modern skincare through scientifically rigorous research.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

NIOD is a Canadian skincare brand founded in 2015 and owned by The Estée Lauder Companies Inc. since 2021.

elcompanies.comglossy.coniod.combeautymatter.com

This page compares some of the most popular Sesderma and NIOD products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Sesderma vs NIOD products

Questions and answers

Sesderma or NIOD: which is better?

NIOD may be better if you prefer fragrance-free formulas, as every product on this page lists no fragrance. Lovi rates NIOD Modulating Glucosides as a High fit for dry, sensitive, and mature skin types.

What is the difference between Sesderma and NIOD?

NIOD offers fragrance-free formulas with high Lovi fit for many skin types, whereas Sesderma includes fragrance in its serum on this page. For acne-prone skin, Sesderma achieves a High fit with its Azelac RU Serum, while NIOD achieves an Average fit with Modulating Glucosides.

Pharmaceutics, 2021Skin Pharmacology and Physiology, 2012

Which is more affordable, Sesderma or NIOD?

The page facts do not provide pricing information for either Sesderma or NIOD, so affordability cannot be compared here.

Which causes fewer breakouts, Sesderma or NIOD?

NIOD provides a High Lovi fit for oily acne-prone skin with its Modulating Glucosides serum, whereas Sesderma's Azelac RU Serum offers an Average fit for that skin type. NIOD's products on this page list no fragrance, while Sesderma's serum contains fragrance.

Pharmaceutics, 2021

Between Sesderma and NIOD, which brand was founded earlier and in which country?

Sesderma was founded earlier in 1989 in Spain, whereas NIOD was founded in 2015 in Canada.

How does the fragrance content compare between the Sesderma and NIOD products listed on the page?

NIOD products on this page list no fragrance, whereas the Azelac RU Serum from Sesderma contains fragrance. This means shoppers looking to avoid added scents will find better options in the NIOD range.

Which company currently owns NIOD and when was it acquired?

NIOD is owned by The Estée Lauder Companies Inc. and was acquired in 2021.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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