Medicube Super Cica Ampoule for oily acne-prone skin
Centella Asiatica Extract
Extract TreeHigh
- SuperiorOily Skin Fit
- HighEffectiveness
- ExcellentSafety
A great choice for oily acne-prone skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Excellent suitability for your oily skin as Centella Asiatica Extract and Madecassoside work synergistically to soothe inflammation and strengthen your skin barrier, addressing your acne and blemishes effectively.
- Licorice Root Extract further aids in seboregulation, helping to manage oiliness and maintain a balanced complexion.
- The formulation is safe for your skin, with no reported irritation risks and a focus on calming ingredients.
How to apply
- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
People Say
★4.5Overall rating based on 100+ reviewsThis ampoule is highly effective for users with acne-prone and sensitive skin, frequently noted for its rapid soothing of redness and calming of active breakouts, acting as a significant aid for compromised skin barriers. A notable portion of users express dissatisfaction with its sticky or tacky finish, which can be problematic for morning routines and makeup application.
Highlights
Soothing & calming Mostly Mentioned
- “Calmed my redness overnight”
- “Stopped blemishes in their tracks”
- “Instant relief for sensitive skin”
Acne & blemish care Often Mentioned
- “Acne calmed down within a day”
- “Prevented new breakouts”
- “Great for hormonal acne”
Small quantity/price Often Mentioned
- “Runs out way too quickly”
- “Expensive for the amount you get”
- “Wish it came in a larger size”
Sticky texture Often Mentioned
- “Terribly sticky finish”
- “Unpleasant sticky feeling in the morning”
- “Too tacky for daytime use”
Hydration & glow Sometimes Noted
- “Gives that inner glow”
- “Leaves skin looking dewy”
- “Hydrating without being heavy”
Packaging/dropper issues Sometimes Noted
- “Dropper doesn't reach the bottom”
- “Hard to use when half empty”
- “Frustrating packaging design”
Sources: lovi.care, reddit.com, youtube.com, oliveyoung.com, yesstyle.com, hwahae.com, and more
Questions and answers
What makes Medicube Super Cica Ampoule a great fit for oily acne-prone skin?
Medicube Super Cica Ampoule is a great fit because centella asiatica extract and madecassoside work together to calm redness and strengthen your skin barrier, which helps manage breakouts. Licorice root extract also helps balance oil levels to keep your skin clear and comfortable. The formula is gentle on oily skin and is unlikely to cause irritation.
Molecules, 2023Indian Journal of Pharmaceutical Sciences, 2016
Which ingredients make this serum a good fit for oily acne-prone skin?
Centella Asiatica Extract and Madecassoside make this serum a great fit because they help soothe inflammation and calm breakouts while strengthening your skin barrier. Licorice Root Extract also aids in managing excess oil to keep your complexion balanced.
What does Centella Asiatica Extract do for oily acne-prone skin?
Centella Asiatica Extract helps calm red spots and supports skin healing in oily, acne-prone skin. It may also help balance moisture and reduce breakouts by soothing irritated areas.
Indian Journal of Pharmaceutical Sciences, 2016Molecules, 2023
What does Madecassoside do for oily acne-prone skin?
Madecassoside helps calm oily, acne-prone skin by reducing redness and soothing irritation while supporting barrier repair. It may help decrease acne blemishes and moisture loss in human skin.
Molecules, 2023Indian Journal of Pharmaceutical Sciences, 2016
Where does this serum go in a skincare routine for oily acne-prone skin?
This serum goes in the evening routine after cleansing and before moisturizing, making it simple and safe for your skin. Using it at night helps calm inflammation and manage oiliness without extra sun exposure risks.
Can I use it with retinol, and in what order?
You can use this treatment with retinol by applying the retinol first and following it with this ampoule to help soothe your skin and keep it calm. This product has a safe formula with no reported irritation risks for oily acne-prone skin.
How often should I use it?
Use this treatment in your evening routine for simplicity and extra safety around sun exposure. It is a great fit for oily acne-prone skin, helping to soothe inflammation and manage oiliness without irritation risks.
Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?
This serum is a great fit for oily acne-prone skin because it contains soothing ingredients like Centella Asiatica Extract and Madecassoside that calm inflammation and manage oiliness without causing breakouts. It has a very safe profile with no reported irritation risks, making it unlikely to clog your pores or cause purging.
Is it fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.
Molecules, 2023Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.
Indian Journal of Pharmaceutical Sciences, 2016Asiatic acid-loaded solid lipid microparticles stabilized with poloxamer-188 reduced porphyrin intensity, enhanced skin barriers, and improved skin hydration and brightness in fifteen participants with mild-to-moderate acne.
International Journal of Pharmaceutics, 2024Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo.
Experimental Dermatology, 2015Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.
Journal of Alternative and Complementary Medicine, 2020A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019
Ingredients
Centella Asiatica Extract, Water, Glycerin, Butylene Glycol, Methylpropanediol, Glycereth-26, 1,2-Hexanediol, Betaine, Licorice Root Extract, Carbomer, Tromethamine, Glycereth-25 Pca Isostearate, Ethylhexylglycerin, Dipotassium Glycyrrhizate, Allantoin, Glyceryl Acrylate Acrylic Acid Copolymer, Dipropylene Glycol, Panthenol, Gardenia Extract, Adenosine, Propanediol, Polyglyceryl-10 Oleate, Centella Asiatica Root Extract, Centella Asiatica Leaf Extract, Nelumbo Nucifera Extract, Pentylene Glycol, Tree Leaf Water, Madecassoside, Biosaccharide Gum-1, Extract Tree, Asiatic Acid, Madecassic Acid, Asiaticoside, Ectoin
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
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PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
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Specialist dermatologist, MBBS, MD, IFAAD
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Dermatology MD
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Elina Nazarenko, MD
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Dermatology and diagnostic consultant
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Victoria Derkova, MS
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Cosmetic chemist, cosmetic development technologist
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