🇮🇹Italy

Medicube PDRN Pink Peptide Ampoule for sensitive skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Medicube PDRN Pink Peptide Ampoule

Average

  • HighNormal Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for sensitive skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate moisturizing and soothing benefits for your normal, sensitive skin, as Hyaluronic Acid and Niacinamide provide hydration and barrier support to help with redness and irritation.
  • The Peptide Complex and Adenosine contribute to improved skin elasticity and general skincare, which are supportive of your concerns.
  • The product is safe for your sensitive skin, containing no harsh ingredients and including soothing components like Hyaluronic Acid and Niacinamide.

How to apply

  • Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
  • Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
  • Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
  • You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
  • Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .

People Say

★4.7Overall rating based on 2.5k+ reviews

Based on a very large amount of data, users consistently report that this ampoule delivers a "glass skin" effect, providing deep hydration and a noticeable plumping effect that benefits dry and aging skin. While it is widely praised for smoothing texture and soothing sensitive skin, results regarding blemish fading are mixed and take longer to appear.

Highlights

  • Deep hydration Mostly Mentioned
    • “skin feels bouncier”
    • “deeply moisturized from within”
    • “plump and radiant”
    • “eliminated deep dryness”
  • Radiant glow Mostly Mentioned
    • “glass skin glow”
    • “healthy dewy look”
    • “complexion looks clearer”
    • “natural inner glow”
  • Fast absorption Often Mentioned
    • “absorbs quickly”
    • “no greasy residue”
    • “lightweight formula”
    • “glides onto skin beautifully”
  • Noticeable fragrance Sometimes Noted
    • “strong rosy scent”
    • “smell isn't my thing”
    • “wish it was fragrance-free”
    • “scent is polarizing”
  • Small volume Sometimes Noted
    • “runs out quickly”
    • “30ml is too small”
    • “pricey for the size”
    • “wish they offered a larger version”
  • Soothing and gentle Sometimes Noted
    • “no irritation”
    • “calmed redness”
    • “good for sensitive skin”
    • “gentle and soothing”
  • Minor breakouts Rarely Noted
    • “small pimple appeared”
    • “caused blemishes on chin”
    • “broke me out slightly”
    • “congestion on forehead”
  • Slight stickiness Rarely Noted
    • “tacky film”
    • “slight sticky feeling”
    • “residue left behind”
    • “hair sticks to face”

Sources: lovi.care, oliveyoung.com, yesstyle.com, hwahae.co.kr, amazon.co.uk, youtube.com, and more

Questions and answers

How well does medicube PDRN Pink Peptide Ampoule work for sensitive skin?

This product works moderately well for sensitive skin, offering basic hydration and soothing benefits to help with redness and irritation. To fit this skin type best, a moisturizing treatment needs maximum hydration and nourishment through a rich blend of barrier-supporting ingredients and soothing agents.

Which ingredients make this serum a good fit for sensitive skin?

Hyaluronic acid and niacinamide make this serum a good fit for sensitive skin by providing hydration and barrier support to help with redness and irritation. To fit sensitive skin even better, this type of product needs extra hydrating and soothing ingredients that calm redness without any risk of irritation while maintaining skin barrier function.

What does Salmon Pdrn do for sensitive skin?

Salmon PDRN helps calm sensitive skin by reducing inflammation and supporting skin repair. It is unlikely to irritate dry or fragile skin while helping it feel more resilient and smooth.

Molecular Medicine Reports, 2023International Journal of Molecular Sciences, 2017

What does Salmon Collagen do for sensitive skin?

Salmon Collagen helps keep sensitive skin hydrated and smooth while improving its overall elasticity. Taking it daily may also help reduce wrinkles and support a strong skin barrier over time.

Journal of Cosmetic Dermatology, 2015International Journal of Dermatology, 2021

Where does this serum go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after your toner and before your moisturizer. Putting treatments in the evening helps keep your routine simple and adds extra safety around sun exposure. Sensitive skin needs gentle hydrating ingredients and soothing components like hyaluronic acid and niacinamide.

Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying it before your retinol at night to help keep your skin calm and hydrated. Because your skin is sensitive, a product of this type works best when it also includes extra barrier-restoring ingredients like ceramides and soothing plant extracts to prevent dryness and irritation.

How often should I use this serum?

This treatment is used in the evening as part of your routine. This timing keeps your routine simple and adds extra safety around sun exposure. To work better for your sensitive skin, a product of this type needs extra soothing components and barrier support.

Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts for sensitive skin because it is free of harsh ingredients and features soothing components like hyaluronic acid and niacinamide. A product of this type needs non-comedogenic hydrators and barrier-supporting ingredients to keep sensitive skin clear and comfortable.

Can I use this serum around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on your body, as it has a safe profile with gentle hydrating and soothing ingredients that are unlikely to cause irritation. Because it is an average fit for sensitive skin, using it here requires gentle hydrators like hyaluronic acid and soothing barrier supporters like niacinamide to keep the delicate skin calm.

Polymers, 2023

Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects.

    International Journal of Cosmetic Science, 2018

  • Horse oil-spread and adenosine-loaded dissolving microneedle patches significantly improved skin elasticity, hydration, dermal density, and wrinkles compared with adenosine-loaded dissolving microneedle patches in 20 women without causing adverse events.

    Journal of Cosmetic Dermatology, 2019

  • Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants.

    International Journal of Molecular Sciences, 2026

  • Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects.

    International Journal of Molecular Sciences, 2025

  • Polydeoxyribonucleotide promotes skin regeneration by increasing ERK phosphorylation, collagen accumulation, and cell proliferation and migration in fibroblasts while inhibiting ERK phosphorylation and inflammatory cytokine expression in keratinocytes.

    Molecular Medicine Reports, 2023

  • A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model.

    Molecules, 2022

  • Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris.

    Journal of Cosmetic Dermatology, 2022

  • Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks.

    International Journal of Molecular Sciences, 2022

  • Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers.

    Marine Drugs, 2023

  • Topical application of CoQ10 improves mitochondrial function in aging skin in vivo, combating cellular signs of aging caused by an age-dependent shift to a functionally anaerobic energy metabolism.

    BioFactors, 2008

  • Encapsulating coenzyme Q10 in lipid nanoparticles for topical use improves skin compatibility, protects against degradation, increases skin penetration, and provides controlled release to counteract aging effects.

    Colloids and Surfaces. B, Biointerfaces, 2023

  • Review of topical administration of carotenoids and coenzyme Q10 loaded in lipid nanoparticles highlights their improved bioavailability, chemical stability, skin absorption, and photoprotective effects.

    Antioxidants, 2021

Ingredients

Salmon Pdrn, Salmon Collagen Complex, Ubiquinone, Ocimum Tenuiflorum, Hyaluronic Acid, Niacinamide, Curcuma Longa Root Extract, Adenosine, Ocimum Sanctum Leaf Extract, Peptide Complex, Rose Pdrn Extract Rosa Damascena Sodium Dna Extract

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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Prices checked 15 Oct – 6 Nov 2026

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.

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