Medicube Collagen Niacinamide Jelly Cream for acne-prone skin
Collagen
Niacinamide
SqualaneHigh
- HighCombination Skin Fit
- HighEffectiveness
- HighSafety
A great choice for acne-prone skin; a few moisturizers fit it even better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your combination skin as niacinamide helps regulate sebum and reduce inflammation, while trehalose provides essential hydration. Collagen and its derivatives further support skin smoothing and texture refinement, addressing your concerns about acne and breakouts.
- The inclusion of various botanical extracts and humectants offers additional soothing and moisturizing benefits, complementing the primary active ingredients.
- The product is safe for your skin, containing no harsh ingredients and featuring soothing components like niacinamide and trehalose.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
People Say
★4.4Overall rating based on 8.6k+ reviewsBased on a very large amount of data, this moisturizer is highly regarded for providing an immediate radiant glow and significant hydration, attributed to its unique cooling jelly texture. Some users find the finish to be sticky or tacky, and a portion of reviews suggest it performs better as a night mask compared to a daytime product.
Highlights
Glass skin glow Mostly Mentioned
- “gives that glass-like glow”
- “skin looks radiant instantly”
- “luminous, dewy appearance”
- “restores natural inner radiance”
Deep hydration Often Mentioned
- “skin drank it up”
- “hydrated all day long”
- “no midday tightness”
- “moisture punch for dry skin”
Sticky/tacky finish Often Mentioned
- “uncomfortably tacky feel”
- “hair sticks to face”
- “leaves sticky residue”
- “pillowcase gets messy”
Cooling jelly texture Sometimes Noted
- “cooling and refreshing”
- “fun, bouncy consistency”
- “melts into skin”
- “soothing on application”
Plumping/firming Sometimes Noted
- “skin feels bouncier”
- “softened fine lines”
- “improved elasticity noticeably”
- “face feels plumped”
Absorption issues Sometimes Noted
- “takes ages to absorb”
- “sits on top of skin”
- “pilling under makeup”
- “felt heavy and thick”
Breakouts/irritation Rarely Noted
- “caused cystic acne”
- “burning sensation on application”
- “redness and itching”
- “tiny bumps appeared”
Fragrance/scent Rarely Noted
- “scent is too strong”
- “slight floral fragrance”
- “smell might bother sensitive noses”
Sources: lovi.care, amazon.com, medicube.us, ulta.com, yesstyle.com, oliveyoung.com, and more
Questions and answers
What makes Medicube Collagen Niacinamide Jelly Cream a great fit for acne-prone skin?
This cream is a great fit for your acne-prone skin because niacinamide helps balance oil and calm redness while trehalose delivers deep hydration. Collagen and plant extracts further smooth your skin texture and soothe breakouts without harsh ingredients.
Which ingredients make this cream a good fit for acne-prone skin?
This cream is a great fit for acne-prone skin because niacinamide helps balance oil and calm redness, while trehalose provides lightweight hydration. Additionally, collagen and its derivatives work to smooth texture and help keep breakouts under control.
What does Collagen do for acne-prone skin?
Collagen does not directly target breakouts, but it helps keep dry or aging acne-prone skin soft and hydrated without clogging pores. Because this skin type often needs lightweight moisture and soothing care, a product of this type needs non-greasy hydrators and calming ingredients to support clear skin.
Current Issues in Molecular Biology, 2024Journal of Drugs in Dermatology, 2019
What does Niacinamide do for acne-prone skin?
Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Where does this cream go in a skincare routine for acne-prone skin?
This cream goes in your morning routine after a hydrating toner and before your SPF, and in your evening routine as the final moisturizing step after your treatment. It is a great fit for acne-prone skin because niacinamide helps regulate oil and reduce inflammation while trehalose provides hydration.
Can I use this cream with retinol, and in what order?
You can use this cream alongside retinol to keep your skin calm and hydrated while helping reduce breakouts. Apply your retinol first, let it absorb, and then smooth on this moisturizer to help lower the chances of dryness or irritation.
Journal of Drugs in Dermatology, 2023The Journal of Dermatological Treatment, 2016
How often should I use this cream?
You can use this cream daily as part of your morning and evening routine. Regular use helps keep acne-prone skin calm and hydrated while supporting smoother texture.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this cream clog pores, cause breakouts or purging for acne-prone skin?
This cream is a great fit and is unlikely to cause breakouts on acne-prone skin, as niacinamide helps calm redness and manage oil while trehalose adds lightweight hydration.
Can I use this cream around the eyes or on my body?
Yes, you can use this moisturizing treatment around the eyes and on the body because it has a very safe profile and lacks harsh ingredients. It helps keep thin or body skin calm and smooth while providing gentle hydration.
Is this cream fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (parfum).
What the research says
Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo.
Skin Research and Technology, 2024Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris.
Journal of Cosmetic Dermatology, 2022Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks.
International Journal of Molecular Sciences, 2022Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers.
Marine Drugs, 2023Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline.
Journal of Cosmetic and Laser Therapy, 2006Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025
Ingredients
Water, Propanediol, Dipropylene Glycol, Butylene Glycol, Methylpropanediol, Diethoxyethyl Succinate, Ethoxydiglycol, Ammonium Acryloyldimethyltaurate Beheneth-25 Methacrylate Crosspolymer, Niacinamide, Trehalose, 1,2-Hexanediol, Chlorella Vulgaris Extract, Collagen, Hydrolyzed Collagen, Cynanchum Atratum Extract, Althaea Rosea Flower Extract, Water-Soluble Collagen, Allium Sativum Bulb Extract, Avena Sativa Kernel Extract Oat Kernel Extract, Bertholletia Excelsa Seed Extract, Brassica Oleracea Italica Extract, Camellia Sinensis Seed Extract, Salmon Egg Extract, Solanum Lycopersicum Fruit Extract Tomato Fruit Extract, Spinach Leaf Extract, Blueberry Fruit Extract, Wine Extract, Polyglyceryl-10 Isostearate, Tromethamine, Glucose, Polyglyceryl-10 Oleate, Ethylhexylglycerin, Fructooligosaccharides, Fructose, Adenosine, Sodium Phytate, Cyanocobalamin, Tocopherol, Pullulan, Glycerin, Hydroxypropyltrimonium Hyaluronate, Squalane, Soluble Proteoglycan, Hydrolyzed Elastin, Sodium Dna, Carbomer, Xanthan Gum, Parfum
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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