iS Clinical Super Serum Advance+ for combination skin
Ascorbic Acid
Sodium Hyaluronate
Arbutin
Tripeptide-1
Madecassic AcidAverage
- HighCombination Skin Fit
- AverageEffectiveness
- HighSafety
Works for combination skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate benefits for your combination skin, as Ascorbic Acid and Arbutin work to brighten and even skin tone, though these ingredients do not directly address your primary concern of oily shine.
- Sodium Hyaluronate provides hydration, which is beneficial for combination skin, but the overall formulation does not offer targeted solutions for managing excess oil.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
People Say
★4.7Overall rating based on 400+ reviewsThis serum is highly regarded for its ability to brighten skin and reduce the appearance of scars and stretch marks. It is often described as a lightweight, fast-absorbing treatment suitable for acne-prone and aging skin, although its high price is a frequent concern among users.
Highlights
Brightens skin tone Mostly Mentioned
- “Gives nice glow”
- “fades dark spots”
- “diminishes uneven tone”
Anti-aging effects Often Mentioned
- “Reduces fine lines”
- “firmer skin”
- “youthful appearance”
Lightweight texture Often Mentioned
- “Absorbs quickly”
- “non-greasy”
- “watery consistency”
Reduces scars/marks Often Mentioned
- “Fades acne scars”
- “helps with stretch marks”
- “improves scar tissue”
High price Often Mentioned
- “Pricey but worth it”
- “expensive investment”
- “let down by price”
Non-irritating Sometimes Noted
- “Good for sensitive skin”
- “no breakouts”
- “calming”
Watery consistency Sometimes Noted
- “Super thin”
- “runny liquid”
- “feels like water”
Application sensation Rarely Noted
- “Mild stinging”
- “slight tingle”
- “temporary burning”
Lack of results Rarely Noted
- “No difference seen”
- “waiting for results”
- “hard to tell”
Packaging/Value Rarely Noted
- “Bottle runs out fast”
- “hard to dispense”
- “dropper issues”
Sources: lovi.care, lovelyskin.com, dermstore.com, dermstreet.com, artofskincare.com, walmart.com, and more
Questions and answers
How well does Super Serum Advance+ work for combination skin?
Super Serum Advance+ works moderately well for combination skin because its ingredients help brighten and even skin tone while providing hydration, though it does not target oily shine. A treatment for combination skin needs ingredients like niacinamide, propolis, or zinc PCA to regulate oiliness while keeping the skin balanced.
Which ingredients make this serum a good fit for combination skin?
Ascorbic acid and arbutin make this serum a good fit for combination skin by brightening and evening skin tone, while sodium hyaluronate adds hydration without causing irritation. However, because it does not manage oily shine, combination skin needs a treatment that includes ingredients like niacinamide, propolis, or zinc PCA to regulate oiliness and balance drier and oilier areas.
What does Vitamin C do for combination skin?
Vitamin C helps brighten dull areas and smooth out uneven texture on combination skin while protecting against daily environmental stress. It may also help keep pores clear and skin firm by supporting collagen production, though drier spots may need an added moisturizer to stay comfortable.
Journal of Cosmetic Dermatology, 2020Journal of Cosmetic Dermatology, 2023
What does Hyaluronic Acid do for combination skin?
Hyaluronic acid is a great fit for combination skin because it quenches dry areas with a boost of hydration while keeping oily zones balanced. Regular use helps smooth out fine lines and makes your skin feel soft and plump without causing irritation.
Dermatology and Therapy, 2021Journal of Drugs in Dermatology, 2011
Where does this serum go in a skincare routine for combination skin?
This treatment goes in the evening routine after cleansing and before moisturizing, as Lovi routines put treatments in the evening for simplicity and extra safety around sun exposure. Combination skin needs products with ingredients that brighten skin tone while also providing targeted solutions for managing excess oil.
Can I use this serum with retinol, and in what order?
You can use this serum with retinol by applying it during your morning routine and saving your retinol for the evening. This separation helps prevent skin irritation while allowing both ingredients to work effectively. To better manage oily shine on combination skin, a product of this type also needs oil-controlling ingredients.
How often should I use this serum?
You can use this treatment in the evening as part of your routine, or occasionally in the morning, starting slowly to see how your skin reacts. It is unlikely to cause irritation on combination skin, but products for this skin also need ingredients that help manage excess oil and shiny areas.
Can this serum clog pores, cause breakouts or purging for combination skin?
This serum is unlikely to cause breakouts or clog pores on combination skin, as it has a safe profile with no harsh ingredients. However, because it lacks targeted solutions for managing excess oil, combination skin needs oil-balancing benefits and ingredients to fully control shine.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.
Journal of Cosmetic Dermatology, 2020Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.
Journal of Cosmetic Dermatology, 2022Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019A non-hydroquinone topical formulation (SKNB19) improved hyperpigmentation by 28.5% in patient self-assessment and 27% in independent reviewer assessment compared with 4% hydroquinone in 18 adult subjects, while showing significantly less irritation and better tolerability.
Journal of Cosmetic Science, 2020Encapsulation of alpha arbutin in an optimized ethosomal gel significantly improved skin melanin reduction, moisture content, and elasticity in human volunteers compared to conventional formulations.
Heliyon, 2023Combining a home-based radiofrequency device and arbutin cream reduced mMASI scores by 25.6% and melanin index by 22.8% at 8 weeks compared to baseline in 38 participants.
Journal of Cosmetic Dermatology, 2025Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.
Journal of Alternative and Complementary Medicine, 2020A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019
Why other serums fit combination skin better
Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo.
BioMed Research International, 2022A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.
Journal of Cosmetic Dermatology, 2024
Ingredients
Water, Ascorbic Acid, Sodium Hyaluronate, Pentylene Glycol, Arbutin, Polyporus Umbellatus Extract Mushroom Extract, Calcium Pantothenate, Zinc Sulfate, Urea, Glucose, Guanidine Hcl, Tripeptide-1, Glycerin, Phenoxyethanol, Asiaticoside, Asiatic Acid, Madecassic Acid
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.