De La Cruz 10% Sulfur Ointment for mature skin
Sulfur
Polyethylene GlycolCaution
- AverageNormal Skin Fit
- AverageEffectiveness
- ConcerningSafety
A poor match for mature skin; the serums alongside fit it better.
- Journal of Evidence-based Medicine, 2020
- Revista de Investigacion Clinica; Organo Del Hospital de Enfermedades de la Nutricion, 2004
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate treatment for acne lesions due to the presence of sulfur, which helps reduce blemishes, but it lacks sufficient humectant or emollient ingredients for optimal hydration of your normal skin.
- While sulfur provides keratolytic action beneficial for acne, its drying nature may potentially worsen the appearance of wrinkles and fine lines, which is your main goal.
How to apply
- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
Questions and answers
Why does Lovi advise caution with De La Cruz 10% Sulfur Ointment for mature skin?
De La Cruz 10% Sulfur Ointment is a poor match for mature skin because its drying nature may worsen the appearance of wrinkles and fine lines, and it lacks enough moisturizing ingredients to keep normal skin hydrated. Mature skin needs a product that is exceptionally safe with no risk of irritation, effectively targets wrinkles and fine lines with high-quality ingredients, performs its intended anti-aging function excellently, and is perfectly suitable for normal skin, along with potent antioxidants, hydrating components, and skin-repairing ingredients.
Which ingredients make this ointment a poor fit for mature skin?
Sulfur and polyethylene glycol make this ointment a poor fit for mature skin because its drying nature may worsen the appearance of wrinkles and fine lines. A treatment for this skin needs nourishing oils, peptides, antioxidants, and hydrating components to smooth and protect it.
What does Sulfur do for mature skin?
Sulfur helps calm acne-prone skin and supports overall clarity with rare mild side effects. To properly care for mature skin, a product of this type needs added moisture-locking ingredients and gentle hydrators to prevent dryness.
What does Polyethylene Glycol do for mature skin?
Polyethylene Glycol acts as a delivery helper in formulas designed for mature skin to help ingredients like antioxidants and vitamins reach deeper layers effectively. When combined with supportive components, it helps keep skin looking firm and smooth over time.
Where does this ointment go in a skincare routine for mature skin?
This treatment goes in the evening routine after cleansing, but it is a poor match for mature skin because its drying nature may worsen the look of wrinkles and fine lines. A product for this skin needs plenty of hydrating ingredients and skin-softening oils to keep it smooth and comfortable.
Can I use this ointment with benzoyl peroxide, and in what order?
You should not use this sulfur ointment with benzoyl peroxide at the same time because both ingredients are very drying and can easily irritate your skin. If you do use both in your routine, apply them on different days or space them widely apart to prevent excessive dryness and peeling.
How often should I use this ointment?
This ointment is a poor fit for mature skin because its drying nature may make fine lines and wrinkles look worse. To care for mature skin properly, a treatment of this type needs extra hydrating and softening ingredients to keep the skin plump and smooth.
Can this ointment clog pores, cause breakouts or purging for mature skin?
This ointment is unlikely to clog pores since sulfur helps clear acne blemishes, but its drying nature may make fine lines and wrinkles on mature skin look more noticeable. A product for this skin needs plenty of hydrating ingredients and rich moisturizers to keep skin smooth and soft.
What the research says
Azelaic acid was probably less effective than benzoyl peroxide in acne treatment response, while showing little or no difference compared to tretinoin, and adverse events were mild and transient across evaluated topical treatments.
Journal of Evidence-based Medicine, 2020Topical application of precipitated sulphur 2-8% petrolatum achieved a 95% clinical and ectoparasitological cure rate in 40 ambulatory scabies patients without relevant adverse effects.
Revista de Investigacion Clinica; Organo Del Hospital de Enfermedades de la Nutricion, 2004Topical 10% benzoyl peroxide and 2%-5% sulfur cream achieved "good" to "excellent" results with no undesirable side effects in 113 consecutive patients with acne.
Canadian Medical Association Journal, 1966Binary systems of trans-resveratrol with polyethylene glycol or beta-cyclodextrin enhanced its antioxidant activity and in vivo skin anti-aging effects compared to trans-resveratrol alone in human keratinocytes and volunteers.
Drug Development and Industrial Pharmacy, 2014Topical application of 30% salicylic acid in polyethylene glycol effectively cleared comedones and papules in 436 patients with acne while causing no stinging, burning, edema, bleeding, or crusting.
Dermatologic Surgery, 2008Glycerol-containing zinc shake lotion and PEG gels produced hydration on nonmoisturized and moisturized skin in healthy volunteers, whereas zinc oil and Lotio Cordes had little impact on stratum corneum hydration.
Skin Pharmacology and Applied Skin Physiology, 2001
Ingredients
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Cosmetic chemist, cosmetologist, aesthetic products developer
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PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
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Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Specialist dermatologist, MBBS, MD, IFAAD
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Dermatology MD
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Elina Nazarenko, MD
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Victoria Derkova, MS
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Cosmetic chemist, cosmetic development technologist
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