🇮🇹Italy

Bioderma Sébium Pore Refiner for mature skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Bioderma Sébium Pore Refiner

Average

  • HighNormal Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for mature skin; other serums fit it better.

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate pore refinement for your normal skin due to salicylic acid and fomes officinalis extract, which help to exfoliate and mattify without causing irritation.
  • While it provides general hydration and pore refining benefits, it lacks specialized anti-aging ingredients to directly target your main goal of wrinkles and fine lines.
  • The product is safe for your normal skin as it contains no harsh or prohibited ingredients.

How to apply

  • Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
  • Apply this serum after your toner and before your moisturizer.
  • Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
  • You can apply the serum on dry skin for the best results against fine lines.
  • Always do a patch test before your first use and avoid the sensitive eye area.

People Say

★4.4Overall rating based on 3.2k+ reviews

Based on a very large amount of data, this product is highly regarded by users with combination to oily skin for its immediate mattifying effect and ability to blur pores, creating a smooth canvas for makeup. A moderate number of users note it can be drying, especially for non-oily areas, while a low number of reviews mention temporary results or skin irritation.

Highlights

  • Instant mattifying Mostly Mentioned
    • “Keeps you shine free”
    • “Controls the oil on my skin”
    • “Matte effect lasts for hours”
  • Excellent primer Often Mentioned
    • “Foundation didn't settle into pores”
    • “Makeup applies smoother”
    • “Better than high-end primers”
  • Pore blurring Often Mentioned
    • “Noticeable difference in size of pores”
    • “Face looks like porcelain”
    • “Pores are definitely less visible”
  • Lightweight texture Sometimes Noted
    • “Soaks in immediately”
    • “Leaves no residue”
    • “Feels like a silky cream”
  • Can be drying Sometimes Noted
    • “Skin looks like sandpaper”
    • “Lack of moisture provided”
    • “Too drying for normal skin”
  • Price vs. quantity Rarely Noted
    • “Quite expensive for the amount”
    • “Tube is small”
    • “Pricey for a primer”
  • Skin irritation Rarely Noted
    • “Stings on open pimples”
    • “Caused breakouts”
    • “Ruined my skin barrier”
  • Temporary results Rarely Noted
    • “Pores are back after washing”
    • “Didn't notice long-term difference”
    • “Effect is temporary”

Sources: lovi.care, bioderma.com, amazon.com, dermstore.com, target.com, influenster.com, and more

Questions and answers

How well does Bioderma Sébium Pore Refiner work for mature skin?

Bioderma Sébium Pore Refiner works as an average fit for mature skin, providing moderate pore refinement and hydration without causing irritation. However, it lacks specialized anti-aging ingredients to directly target wrinkles and fine lines. A treatment for mature skin needs potent antioxidants, hydrating components, skin-repairing ingredients, and nourishing oils and peptides to effectively address fine lines while supporting overall skin health.

Which ingredients make this cream a good fit for mature skin?

Salicylic acid and mushroom extract make this cream a moderate fit by helping to exfoliate and mattify normal skin. To better suit mature skin, a product of this type needs specialized anti-aging ingredients, potent antioxidants, hydrating components, and skin-repairing ingredients that target wrinkles and fine lines.

Journal of Cosmetic Dermatology, 2024Journal of Drugs in Dermatology, 2023

What does Fluidactiv Patent do for mature skin?

Fluidactiv Patent helps normalize sebum quality to keep pores clear and reduce breakouts. It is beneficial for mature skin dealing with adult blemishes, helping maintain a smooth and balanced complexion.

What does Salicylic Acid do for mature skin?

Salicylic acid helps smooth and firm mature skin by boosting collagen and elasticity while reducing roughness and wrinkles. It is unlikely to cause irritation when used correctly, but this skin type also needs extra hydrating ingredients to stay soft and plump.

Aesthetic Plastic Surgery, 2025

Where does this cream go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and before moisturizing, starting once a week to see how your skin adjusts. Mature skin also needs products with specialized anti-aging ingredients like retinol or peptides to effectively target wrinkles and fine lines.

Can I use this cream with niacinamide, and in what order?

Yes, you can use this cream with niacinamide by applying niacinamide first and following with this treatment once it absorbs. This combination helps keep your skin smooth and clear while being safe and unlikely to cause irritation.

How often should I use this cream?

This treatment is used in the evening once a week to start, and can be used more often if your skin tolerates it well and shows good results. Because this product fits mature skin only moderately, this skin needs specialized anti-aging ingredients like retinoids and antioxidants to target wrinkles and fine lines.

Can this cream clog pores, cause breakouts or purging for mature skin?

This cream is unlikely to clog pores or cause breakouts for mature skin, as it contains salicylic acid to help keep pores clear. However, it may sometimes feel a bit drying.

Journal of Cosmetic Dermatology, 2024Journal of Drugs in Dermatology, 2023

Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

What the research says

  • Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability.

    Journal of Cosmetic Dermatology, 2024

  • The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle.

    Journal of Drugs in Dermatology, 2023

  • A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase.

    BioMed Research International, 2020

  • Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients.

    CMAJ, 2010

  • Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy.

    Journal of Cosmetic Dermatology, 2024

  • Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients.

    Journal of the American Academy of Dermatology, 2010

  • White button mushroom extract treatment increased VEGF densities, EGF, PCNA, and collagen fibers, while decreasing apoptotic cells and limiting TGF-beta and CD4 reactions in ICR mice and chorioallantoic culture, indicating beneficial effects on skin regeneration and injury.

    Microscopy Research and Technique, 2012

  • Topical application of a 2% cream containing combined fruit extracts for 56 days significantly reduced wrinkle depth by 11.5%, length by 10.07%, and area by 29.55% in 21 female subjects compared to a placebo.

    Clinical, Cosmetic and Investigational Dermatology, 2015

  • A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris.

    Clinical, Cosmetic and Investigational Dermatology, 2015

  • Topical application of Ginkgo biloba cream for two weeks reduced wrinkles and improved skin shape, texture, and tautness in human volunteers compared to baseline.

    Drug Development and Industrial Pharmacy, 2023

Why other serums fit mature skin better

Ingredients

Water, Methyl Methacrylate Crosspolymer, Dipropylene Glycol, Cyclopentasiloxane, Cyclohexasiloxane, Dimethicone, Glycerin, Butylene Glycol, Fomes Officinalis Extract Mushroom Extract, Sodium Polyacrylate, Salicylic Acid, Dodecyl Gallate, Ginkgo Biloba Leaf Extract, Mannitol, Xylitol, Rhamnose, Fructooligosaccharides, Laminaria Ochroleuca Extract, Silica, Trideceth-6, C30-45 Alkyl Cetearyl Dimethicone Crosspolymer, Lauryl Peg Ppg-18 18 Methicone, Caprylic Capric Triglyceride, Paraffinum Liquidum Mineral Oil, Pentylene Glycol, 1,2-Hexanediol, Peg Ppg-18 18 Dimethicone, Caprylyl Glycol, Propylene Glycol, Sodium Hydroxide, Citric Acid, Disodium Edta, Parfum

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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Prices checked 16 Oct – 4 Nov 2026

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

How does it fit your skin?

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