Perricone MD Nutritive Cleanser for dry skin
Alpha Lipoic Acid
Copper Gluconate
Zinc Gluconate
Dimethyl Mea Dmae
Aha Complex
Low
- LowDry Skin Fit
- AverageEffectiveness
- ConcerningSafety
A weak match for dry skin; the cleansers alongside fit it better.
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate cleansing for your dry skin due to Sodium Laureth Sulfate and Lauryl Glucoside, which help decongest pores but may strip natural oils. The absence of effective humectants or emollients means it does not adequately address dryness or flakiness.
- While the formula is free from harsh ingredients and suitable for sensitive skin, its cleansing action is not optimized for dry or flaky skin types.
How to apply
- Use this cleanser AM and PM every day to keep your skin clean. Start using it daily right away since your skin is not sensitive.
- Apply this cleanser as the very first step in your morning routine and right after your pre-cleanser in the evening. Follow with your toner and moisturizer afterwards.
- Gently massage a small amount of cleanser onto your face using soft circular motions. Rinse thoroughly with lukewarm water and pat dry with a clean towel.
- Apply this cleanser on slightly damp skin for a comfortable and refreshing wash. This helps maintain your skin's natural moisture while cleansing away dirt.
- Avoid getting the cleanser directly into your eyes to prevent any irritation. Do a simple patch test before your first use to ensure your skin likes it.
People Say
★4.5Overall rating based on 1.5k+ reviewsBased on a very large amount of data, users frequently praise this gel cleanser for its ability to thoroughly remove makeup and oil without stripping the skin's natural moisture barrier, making it a favorite for those with normal to dry skin. Many report softer, brighter, and more radiant skin after use, though a notable minority of users express dissatisfaction with the product's strong fragrance and the recent packaging change from a glass bottle to a plastic tube.
Highlights
Gentle and non-drying Mostly Mentioned
- “never dry or tight”
- “leaves skin soft”
- “doesn't strip moisture”
- “gentle on sensitive skin”
Effective makeup remover Often Mentioned
- “removes all makeup”
- “takes off mascara”
- “cleans thoroughly”
- “melts away dirt”
Anti-aging benefits Sometimes Noted
- “firming effect”
- “helps with fine lines”
- “youthful glow”
- “great for mature skin”
Improves skin texture Sometimes Noted
- “skin looks brighter”
- “smoother complexion”
- “pores look smaller”
- “improves tone”
Packaging issues Sometimes Noted
- “hate the new tube”
- “cap breaks easily”
- “leaks in travel”
- “hard to control amount”
Unpleasant scent Sometimes Noted
- “smells like perfume”
- “strong floral scent”
- “fragrance is awful”
- “scent is overpowering”
Eye irritation Rarely Noted
- “burns my eyes”
- “stings if near eyes”
- “irritates eyes”
- “have to be careful”
High price point Rarely Noted
- “very pricey”
- “expensive for a cleanser”
- “wait for a sale”
- “cost is high”
Sources: lovi.care, nordstrom.com, dermstore.com, perriconemd.com, and more
Questions and answers
Why is Perricone MD Nutritive Cleanser a weak match for dry skin?
Perricone MD Nutritive Cleanser is a weak match for dry skin because its cleansing agents may strip natural oils and it lacks effective humectants or emollients to address dryness. To truly fit dry skin, a cleanser of this type needs hydrating ingredients and soothing agents that clean without removing moisture.
Which ingredients make this cleanser a poor fit for dry skin?
Sodium Laureth Sulfate and Lauryl Glucoside make this cleanser a weak match for your dry skin because they may strip natural oils and reduce moisture. A cleanser for dry skin needs effective hydrating and soothing ingredients that clean without stripping moisture.
What does Alpha Lipoic Acid do for dry skin?
Alpha-lipoic acid helps make dry skin feel smooth and soft by supporting moisture levels and improving texture. When combined with other antioxidants or hydrating ingredients, it may also help protect the skin barrier and maintain a healthy appearance.
Photochemistry and Photobiology, 2012The British Journal of Dermatology, 2003
What does Copper Gluconate do for dry skin?
Copper Gluconate helps keep dry skin balanced by supporting moisture retention and calm skin surfaces. It assists in maintaining healthy skin texture and is unlikely to cause irritation when used in your daily routine.
Where does this cleanser go in a skincare routine for dry skin?
This cleanser is used in both your morning and evening routine, but it is a weak match for dry skin because it may strip natural oils and lacks ingredients that add moisture. A cleanser for dry skin needs gentle cleansing agents along with soothing humectants and rich emollients to keep the skin soft and smooth.
The Journal of Dermatological Treatment, 2022International Journal of Pharmaceutics, 2026
Can I use this cleanser with retinol, and in what order?
You can use this cleanser with retinol, but because it may strip natural oils from dry skin, you should follow it with a gentle moisturizer or barrier-restoring ingredients to keep skin soft and comfortable.
How often should I use this cleanser?
This cleanser is a weak match for dry skin because it may strip natural oils and lacks ingredients to soothe dryness, so a dry skin routine needs a gentle cleanser packed with hydrating humectants and rich emollients instead.
The Journal of Dermatological Treatment, 2022International Journal of Pharmaceutics, 2026
Can this cleanser clog pores, cause breakouts or purging for dry skin?
This cleanser is unlikely to clog pores or cause breakouts on dry skin because it rinses away cleanly, though it does not help with dryness or flakiness. A cleanser for dry skin needs gentle cleansing ingredients combined with rich emollients and hydrating humectants to keep skin soft and smooth.
Can I use this cleanser around the eyes or on my body?
You can use this cleanser on the body, but it is less suited for the thin skin around the eyes because its strong cleansing action may strip natural oils and increase moisture loss. Dry skin needs a cleanser that includes gentle hydrating ingredients and skin-softening oils to protect against flakiness.
Surgical and Radiologic Anatomy, 2002International Journal of Pharmaceutics, 2026
Is this cleanser fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (parfum).
What the research says
Topical 30% P407 gel loaded with ALA cubosomes reduced facial lines, nearly resolved fine lines in the periorbital and upper lip areas, and improved skin color and texture without irritation or peeling in volunteers.
European Journal of Pharmaceutics and Biopharmaceutics, 2014Application of 5% cubosomal alpha lipoic acid gel twice daily for 6 months significantly improved global aesthetic scores and increased epidermal thickness compared to placebo in 20 aging female faces.
Journal of Cosmetic Dermatology, 2017Treatment with a cream containing 5% alpha-lipoic acid for 12 weeks reduces skin roughness by an average of 50.8% compared to 40.7% with placebo in women with photoaged facial skin.
The British Journal of Dermatology, 2003Zinc gluconate induced alpha2, alpha3, alphaV, and alpha6 integrins, copper gluconate induced alpha2, alpha6, and beta1, and manganese gluconate induced most studied integrins in cultured keratinocytes.
The British Journal of Dermatology, 1999A dermocosmetic cream containing Punica granatum Pericarp extract, Salicylic acid, Niacinamide, Zinc gluconate, and Aqua Posae Filiformis significantly decreased inflammatory, non-inflammatory, and total lesion counts in subjects with mild to moderate acne compared to untreated hemi-faces after 15 days.
Journal of Cosmetic Dermatology, 2026Daily use of a deep cleansing gel containing salicylic acid 2%, zinc gluconate 0.2% and lipohydroxy acid 0.05% significantly reduced total lesion count by 56.3% after 84 days in 35 subjects with mild to moderate truncal acne.
Clinical, Cosmetic and Investigational Dermatology, 2023Different strains of Propionibacterium acnes modulate cutaneous innate immunity with varying pro-inflammatory potentials, with P. acnes type III showing the highest and P. avidum the weakest, and zinc gluconate down-regulates the expression of most induced immune markers.
Experimental Dermatology, 2013Daily application of 3% DMAE facial gel for 16 weeks safely and efficaciously mitigates forehead lines and periorbital fine wrinkles, improves lip shape and fullness and overall aging skin appearance, and increases skin firmness compared to placebo.
American Journal of Clinical Dermatology, 2005A gel containing 3% 2-dimethylaminoethanol (DMAE) increased skin firmness, demonstrated by increased shear wave velocity in 30 volunteers compared to a formulation without DMAE.
Skin Research and Technology, 2002A DMAE-based formulation increased dermal and collagen fiber thickness in hairless mice and enhanced stratum corneum water content in human forearm skin compared to control formulations, without significantly modifying mechanical properties.
Die Pharmazie, 2009
Why other cleansers fit dry skin better
- Sodium laureth sulfate in this cleanser
Treatment with sodium lauryl ether sulfate emulsion increased transepidermal water loss and skin surface pH while reducing stratum corneum hydration and natural moisturizing factor content compared to diacyl phospholipid emulsions and controls, irrespective of UVA irradiation, in eight healthy volunteers.
International Journal of Pharmaceutics, 2026 A formulation containing glycerol (5%) and xylitol (5%) applied twice daily for 14 days increased skin hydration, filaggrin protein quantity, interdigitation index, and biomechanical properties, and decreased transepidermal water loss compared to untreated and vehicle-treated skin in twelve volunteers with dry skin.
Acta Dermato-venereologica, 2017Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.
Indian Journal of Pharmaceutical Sciences, 2016
Ingredients
Water, Sodium Laureth Sulfate, Lauryl Glucoside, Cocamidopropyl Betaine, Ppg-2 Hydroxyethyl Coco Isostearamide, Dimethyl Mea Dmae, Citric Acid, Sodium Chloride, Thioctic Acid Alpha-Lipoic Acid, Disodium Edta, Parfum, Benzophenone-4, Magnesium Aspartate, Zinc Gluconate, Copper Gluconate, Methylchloroisothiazolinone, Methylisothiazolinone
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.