Clinique Dramatically Different Moisturizing Lotion+ for dry skin
Glycerin
Sodium Hyaluronate
Sesamum Indicum Oil
Cucumis Sativus Fruit Extract
Hordeum Vulgare Extract
Average
- HighDry Skin Fit
- AverageEffectiveness
- HighSafety
Works for dry skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate hydration for your dry skin, as glycerin and petrolatum provide emollient benefits to smooth and hydrate. Urea further supports skin barrier function, though a more potent humectant could enhance plumping.
- The formula is generally safe for your dry skin, with soothing ingredients like urea and glycerin present and no harsh irritants identified.
- This product provides basic hydration and emollient benefits suitable for dry or flaky skin.
How to apply
- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
People Say
★4.5Overall rating based on 15.0k+ reviewsBased on a very large amount of data, this lotion is a highly regarded staple for dry and combination skin, frequently praised for restoring the moisture barrier and leaving a soft, non-greasy finish. Most users report improved hydration and a healthy glow. A moderate number of users experienced breakouts or found the texture too heavy for oily areas.
Highlights
Effective hydration Mostly Mentioned
- “Keeps my dry patches at bay all day”
- “Skin feels instantly plump and quenched”
- “Restored my moisture barrier after over-exfoliating”
- “Provides all-day comfort without tightness”
Lightweight texture Often Mentioned
- “Absorbs quickly without feeling sticky”
- “Silky consistency that spreads easily”
- “Doesn't feel heavy or mask-like”
- “Sinks in within seconds”
Gentle/fragrance-free Sometimes Noted
- “Great for my sensitive, reactive skin”
- “No strong scents to irritate my nose”
- “Soothing on redness and irritation”
- “Doesn't sting even when my skin is raw”
Makeup compatibility Sometimes Noted
- “Foundation glides on perfectly over it”
- “Doesn't pill under sunscreen or makeup”
- “Creates a smooth, hydrated canvas”
- “My makeup looks less cakey”
Caused breakouts Sometimes Noted
- “Woke up with whiteheads on my chin”
- “Caused deep cystic acne after a week”
- “Too rich, clogged my pores”
- “My skin cleared up once I stopped using it”
Formula change Rarely Noted
- “New formula isn't as good as the original”
- “Caused a reaction unlike the old version”
- “Miss the yellow bottle from 10 years ago”
- “Feels different than I remember”
Greasy residue Rarely Noted
- “Left an oily film on my T-zone”
- “Looked like a greaseball by noon”
- “Sits on top of skin rather than absorbing”
- “Too shiny for daytime use”
Unpleasant scent Rarely Noted
- “Has a weird plastic-like smell”
- “Smells a bit like stale chemicals”
- “No fragrance, but the natural scent is off-putting”
- “Smells medicinal in a bad way”
Sources: lovi.care, ulta.com, sephora.com, clinique.com, amazon.com, makeupalley.com, and more
Questions and answers
How well does Clinique Dramatically Different Moisturizing Lotion+ work for dry skin?
This moisturizer provides moderate hydration for dry skin, using glycerin, petrolatum, and urea to smooth and soften. A product of this type needs stronger moisture-binding ingredients and rich nourishing agents to give dry skin optimal hydration and full barrier support.
Which ingredients make this moisturizer a good fit for dry skin?
Glycerin, petrolatum, and urea make this moisturizer a fit for dry skin by smoothing, hydrating, and supporting the skin barrier. A moisturizer for dry skin needs highly effective soothing ingredients, strong moisture-retaining agents like hyaluronic acid and glycerin, and rich nourishing components to ensure optimal hydration and barrier support.
What does Glycerin do for dry skin?
Glycerin helps dry skin by drawing in moisture and keeping it locked in, which makes the skin feel much softer and smoother. It also supports your natural skin barrier to stop water from escaping easily. A product for dry skin needs extra ingredients like hyaluronic acid and soothing plant extracts to truly calm and hydrate dry patches.
Clinical, Cosmetic and Investigational Dermatology, 2017The British Journal of Dermatology, 2008
What does Hyaluronic Acid do for dry skin?
Hyaluronic acid draws moisture into dry skin, giving an immediate and lasting boost in hydration that helps smooth out fine lines and soften rough patches. It is very gentle and unlikely to cause irritation while improving overall skin smoothness and plumpness.
Dermatology and Therapy, 2021Journal of Drugs in Dermatology, 2011
Where does this moisturizer go in a skincare routine for dry skin?
This moisturizer goes after your hydrating toner in the morning and after your treatment in the evening. Regular use of a moisturizer helps improve visual dryness and keeps dry skin feeling smooth.
Can I use this moisturizer with retinol, and in what order?
You can use this moisturizer with retinol by applying the retinol first and following with the moisturizer. This helps keep dry skin soft and smooth while lowering the likelihood of irritation during treatment.
How often should I use this moisturizer?
You can use this moisturizer twice a day, in the morning and evening, to help keep your dry skin smooth and comfortable. Daily use of such moisturizers helps improve skin moisture and supports the skin barrier.
Can this moisturizer clog pores, cause breakouts or purging for dry skin?
This moisturizer may cause breakouts for some people with dry skin, as a moderate number of reviewers complain about this issue. To better prevent breakouts while keeping dry skin hydrated, a product of this type needs non-clogging ingredients and lightweight moisturizers that balance moisture without feeling heavy.
Can I use this moisturizer around the eyes or on my body?
You can use this moisturizer on your body and around the eyes, as its formula provides basic hydration and soothing benefits that are generally safe for dry skin. Dry skin types need richer hydrators with stronger water-holding ingredients and barrier-supporting lipids to fully smooth and plump.
Is this moisturizer fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical application of sesame oil combined with standard care significantly reduced infusion-related phlebitis in adults compared to a control condition, with a risk ratio of 0.54.
Complementary Therapies in Medicine, 2025Sesamol loaded silver nanoparticles gel showed a twofold increase in skin permeation and higher antioxidant activity compared to conventional formulations, demonstrating potential for topical wound healing delivery.
Current Pharmaceutical Design, 2024Treatment with moderately ozonated sesame oil accelerates cutaneous wound closure and enhances cell response, angiogenesis, and VEGF and cyclin D1 expression in SKH1 mice compared to oil with lower or higher peroxide values and controls.
Wound Repair and Regeneration, 2011Transgenic cucumber expressing poly-γ-glutamic acid synthesis genes increased water content by 6-14%, reduced water loss by 11-12%, decreased facial wrinkles and roughness by 19.58% and 24.97%, decreased skin melanin by 5.27%, and improved facial elasticity in human skin and zebrafish compared to controls.
International Journal of Biological Macromolecules, 2024Copper Oxide nanoparticles synthesized using cucumber extract exhibited antibacterial, antifungal, UV protection, and reactive-oxygen species inhibition properties with low cellular toxicity and skin-rejuvenating effects when incorporated into skin cream.
Endocrine, Metabolic & Immune Disorders Drug Targets, 2021Topical treatment with Holothuria parva extract gel showed significant wound contraction compared to the negative control in full-thickness wounded rats.
The International Journal of Lower Extremity Wounds, 2024
Why other moisturizers fit dry skin better
Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers.
International Journal of Medical Sciences, 2021Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.
Indian Journal of Pharmaceutical Sciences, 2016Topical oil-in-water and water-in-oil emulsions containing glyceryl glucoside, natural moisturizing factors, and ceramide significantly improved skin hydration and barrier function while reducing visible dryness and tactile roughness in subjects with very dry skin compared to untreated sites and vehicles.
The Journal of Clinical and Aesthetic Dermatology, 2012
Ingredients
Water, Mineral Oil, Paraffinum Liquidum, Huile Minérale, Glycerin, Petrolatum, Stearic Acid, Glyceryl Stearate, Sesamum Indicum Oil, Urea, Lanolin Alcohol, Triethanolamine, Hordeum Vulgare Extract, Extrait Dorge, Cucumis Sativus Fruit Extract, Helianthus Annuus Seedcake Sunflower Seedcake, Propylene Glycol Dicaprate, Sodium Hyaluronate, Butylene Glycol, Pentylene Glycol, Trisodium Edta, Phenoxyethanol, Ci 15985, Yellow 5 Ci 19140, Red 33 Ci 17200
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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