Perricone MD Cold Plasma Plus+ Sub-D/Neck for combination skin
Dmae
Niacinamide
Tetrahexyldecyl Ascorbate
Acetyl Tetrapeptide-9
Glycerin
High
- AverageCombination Skin Fit
- AverageEffectiveness
- ExcellentSafety
A great choice for combination skin; a few sunscreens fit it even better.
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent moisturizing for your combination skin, as glycerin and dimethicone provide hydration and smoothness, while niacinamide helps control oil and offers antioxidant benefits.
- Bisabolol further supports skin comfort by soothing potential irritation, ensuring a gentle yet effective experience.
- The product is safe for your skin, containing no harsh ingredients and including beneficial components for overall skin health.
How to apply
- Apply this moisturizing sunscreen AM daily to protect your skin and control shine. Reapply as needed throughout the day.
- Use it as the final step of your morning routine after applying your moisturizer. It combines hydration and sun protection in one.
- Gently smooth a nickel-sized amount evenly over your face, avoiding harsh rubbing. Let it absorb fully before putting on makeup.
- Apply it directly to clean, dry skin for the best oil-controlling finish. Ensure your face is completely dry so the product sets properly.
- Avoid the immediate eye area during application. Do a patch test before your first use to check for any sensitivity.
People Say
★4.3Overall rating based on 2.2k+ reviewsBased on a very large amount of data, users frequently report visible improvements in skin texture and firmness along the jawline and neck, describing the skin as smoother and more hydrated. A significant number of reviewers consistently complain about a strong, unpleasant scent often compared to pickles or fish, and some experience issues with the product pilling under makeup.
Highlights
Unpleasant smell Mostly Mentioned
- “smells like pickles”
- “fishy odor”
- “scent is unbearable”
- “funky chemical smell”
Improves skin texture Often Mentioned
- “crepiness is gone”
- “skin feels smoother”
- “softens neck lines”
- “texture is refined”
Visibly tightens and firms Often Mentioned
- “jawline looks more defined”
- “helped with sagging skin”
- “tightened my turkey neck”
- “noticed firmness in weeks”
Hydrating formula Sometimes Noted
- “very moisturizing”
- “skin feels hydrated”
- “plumps the skin”
- “great for dry neck”
Lightweight and absorbent Sometimes Noted
- “absorbs quickly”
- “not greasy”
- “lightweight consistency”
- “sinks right in”
High price point Sometimes Noted
- “too expensive”
- “pricey for the amount”
- “not worth the money”
- “cost is prohibitive”
Caused irritation Rarely Noted
- “broke my neck out”
- “caused red rash”
- “skin felt burning”
- “itchy reaction”
Pilling or flaking Rarely Noted
- “rolls off skin”
- “flakes when touched”
- “pills under makeup”
- “residue rubs off”
Sources: lovi.care, perriconemd.com, nordstrom.com, macys.com, ulta.com, dermstore.com, and more
Questions and answers
What makes Perricone MD Sub-D/Neck a great fit for combination skin?
This product is a great fit because glycerin and dimethicone bring hydration and smoothness to your combination skin, while niacinamide helps control oil. Bisabolol also calms potential irritation, keeping the skin comfortable.
Which ingredients make this cream a good fit for combination skin?
This cream is a great fit because glycerin and dimethicone bring much-needed hydration and smoothness, while niacinamide helps control oil. Additionally, bisabolol soothes potential irritation to keep your skin comfortable and balanced.
What does DMAE do for combination skin?
DMAE helps firm combination skin and smooth out fine lines when used daily, though a product of this type needs added hydrating ingredients to keep dry areas soft while balancing oilier zones.
American Journal of Clinical Dermatology, 2005Skin Research and Technology, 2002
What does Niacinamide do for combination skin?
Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Where does this cream go in a skincare routine for combination skin?
This moisturizing spf goes in the morning routine after your hydrating toner and before your sunscreen step. It provides hydration and smoothness while helping control oil, making it a great fit for your skin type.
Can I use this cream with retinol, and in what order?
You can use this cream alongside retinol by applying the retinol first, letting it absorb, and then following with this moisturizer. This helps keep your combination skin smooth and hydrated while minimizing potential dryness or irritation from the retinol.
How often should I use this cream?
This moisturizing spf is a great fit for your combination skin, providing deep hydration and smoothness while helping control oil and soothe potential irritation. Daily use helps maintain skin health and moisture without harsh ingredients.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this cream clog pores, cause breakouts or purging for combination skin?
This cream is unlikely to clog pores or cause breakouts for combination skin, as it has a safe formula with gentle ingredients that keep your skin calm and balanced. It provides great hydration and smoothness while helping to control oil without harsh additives.
Is this cream fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (benzyl alcohol).
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Daily application of 3% DMAE facial gel for 16 weeks safely and efficaciously mitigates forehead lines and periorbital fine wrinkles, improves lip shape and fullness and overall aging skin appearance, and increases skin firmness compared to placebo.
American Journal of Clinical Dermatology, 2005A gel containing 3% 2-dimethylaminoethanol (DMAE) increased skin firmness, demonstrated by increased shear wave velocity in 30 volunteers compared to a formulation without DMAE.
Skin Research and Technology, 2002A DMAE-based formulation increased dermal and collagen fiber thickness in hairless mice and enhanced stratum corneum water content in human forearm skin compared to control formulations, without significantly modifying mechanical properties.
Die Pharmazie, 2009Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline.
Journal of Cosmetic and Laser Therapy, 2006Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.
Journal of Cosmetic Dermatology, 2022The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012
Ingredients
Water, Dimethicone, Cyclopentasiloxane, Glycerin, Niacinamide, Ethylhexyl Methoxycrylene, Pentylene Glycol, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Polyester-8, Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Tetrahexyldecyl Ascorbate, Thioctic Acid, Acetyl Tetrapeptide-9, Diethylhexyl Syringylidenemalonate, Hydrogenated Lecithin, Bisabolol, Xanthan Gum, Hydrogenated Phosphatidylcholine, Mannitol, Benzyl Alcohol, Stearic Acid, Isohexadecane, Polysilicone-11, Polysorbate 60, Sorbitan Isostearate, Caprylic Capric Triglyceride, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate, Aluminum Hydroxide
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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