numbuzin Goodbye Blemish Serum for acne-prone skin
Niacinamide
Hippophae Rhamnoides Extract
Curcuma Longa Root Extract
Centella Asiatica Extract
Ascorbic AcidHigh
- HighCombination Skin Fit
- HighEffectiveness
- HighSafety
A great choice for acne-prone skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- This serum is highly suitable for your combination skin, as niacinamide helps regulate sebum production while multiple forms of vitamin C and Hippophae Rhamnoides Extract work to brighten your skin tone and target inflammation associated with acne and blemishes.
- The inclusion of Centella Asiatica Extract and Chamomilla Recutita Flower Extract provides soothing benefits, complementing the active ingredients and enhancing overall skin comfort.
- The product has a very good safety profile, with no harsh ingredients and a focus on calming components, making it safe for your skin.
How to apply
- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
People Say
★4.6Overall rating based on 400+ reviewsUsers with acne-prone and sensitive skin frequently praise this serum for its lightweight, gel-like texture that effectively soothes inflammation and gradually fades post-acne hyperpigmentation. While the majority report a brighter, more even complexion without irritation, a subset of users notes that visible results require patience and consistent use over several weeks.
Highlights
Lightweight texture Mostly Mentioned
- “absorbs instantly”
- “non-greasy finish”
- “spreads like butter”
- “refreshing gel consistency”
Fades dark spots Often Mentioned
- “faded my dark spots”
- “fades pimple marks faster”
- “even out my tone”
- “helped with brightening”
Gentle formula Often Mentioned
- “sensitive skin approved”
- “mild formula”
- “no stinging”
- “didn't irritate my skin”
Soothing and calming Often Mentioned
- “calms down redness”
- “soothes sensitive skin”
- “reduced inflammation”
- “keeps acne at bay”
Slow results Sometimes Noted
- “didn't notice much”
- “takes patience”
- “gradual process”
- “hard to see results”
Caused breakouts Rarely Noted
- “gave me pimple”
- “broke me out”
- “caused small breakouts”
- “skin disliked it”
Price vs size Rarely Noted
- “expensive for a serum”
- “small bottle”
- “pricey for the amount”
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Questions and answers
What makes Numbuzin Goodbye Blemish Serum a great fit for acne-prone skin?
Numbuzin Goodbye Blemish Serum is a great fit because niacinamide helps balance oil, while vitamin C and fruit extracts target inflammation and brighten dark spots. Centella Asiatica extract and chamomile add extra comfort, and the gentle formula is unlikely to irritate your skin.
Postepy Dermatologii I Alergologii, 2014Indian Journal of Pharmaceutical Sciences, 2016
Which ingredients make this serum a good fit for acne-prone skin?
This serum is a great fit for your acne-prone skin because niacinamide helps balance oil, while vitamin C and seabuckthorn extract target redness and dark spots. Centella asiatica and turmeric extracts also help calm irritation and keep your skin comfortable.
Postepy Dermatologii I Alergologii, 2014Indian Journal of Pharmaceutical Sciences, 2016
What does Niacinamide do for acne-prone skin?
Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
What does Sea Buckthorn Extract do for acne-prone skin?
Sea buckthorn extract helps balance acne-prone skin by reducing excess oil production. Clinical evaluation shows that topical emulsions containing this extract significantly decrease skin sebum levels in people with mild to moderate acne.
Where does this serum go in a skincare routine for acne-prone skin?
This serum goes in the evening routine, as treatments with active ingredients are placed at night for simplicity and extra safety around sun exposure. It has a very good safety profile and is unlikely to irritate your skin.
Can I use this serum with retinol, and in what order?
You can use this serum with retinol by applying the treatment after your cleanser and before your moisturizer, but it is best to alternate nights or use one in the morning and one at night to keep your skin calm. This helps you get the brightening and soothing benefits without overwhelming your skin with too many strong actives at once.
How often should I use this serum?
You can use Numbuzin Goodbye Blemish Serum in your evening routine, applying it after your cleansing toner and before your moisturizer. It is unlikely to irritate your acne-prone skin, as it features a gentle formula with soothing ingredients like centella asiatica and niacinamide to help calm redness and control oil.
Postepy Dermatologii I Alergologii, 2014Indian Journal of Pharmaceutical Sciences, 2016
Can this serum clog pores, cause breakouts or purging for acne-prone skin?
This serum is unlikely to cause breakouts for acne-prone skin since it features a very safe formula centered on calming ingredients and niacinamide to help regulate oily skin. While a small number of reviewers report breakouts, the product's focus on soothing plant extracts helps keep skin comfortable.
Postepy Dermatologii I Alergologii, 2014Indian Journal of Pharmaceutical Sciences, 2016
Is this serum fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (citral and limonene).
What the research says
Topical emulsions containing Hippophae rhamnoides and Cassia fistula plant extracts significantly reduced skin sebum contents compared to placebo in patients with grade I and grade II acne vulgaris.
Postepy Dermatologii I Alergologii, 2014A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.
Journal of Cosmetic Dermatology, 2020Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.
Indian Journal of Pharmaceutical Sciences, 2016Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.
Molecules, 2023Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical application of a sea buckthorn fruit extract formulation significantly reduced skin sebum secretion in 10 healthy human volunteers compared to the control base over an 8-week period.
Journal of Pharmacy & Bioallied Sciences, 2010Topical application of a 5% Hippophae rhamnoides oil-in-water emulsion significantly improved skin hydration (p=0.0003) and transepidermal water loss (p=0.0087) compared to a placebo base formulation in 13 healthy male subjects over 84 days.
Pakistan Journal of Pharmaceutical Sciences, 2014Sea buckthorn seed oil prevents UV-induced disturbances in redox balance and lipid metabolism in human keratinocytes and fibroblasts by reducing reactive oxygen species and lipid peroxidation products while enhancing antioxidant levels.
Antioxidants, 2018Topical application of curcumin or turmeric treats various skin conditions by leveraging antioxidant, anti-inflammatory, and antimicrobial properties.
Skin Pharmacology and Physiology, 2023Topical formulations of curcumin target oxidative damage and inflammation to improve wound healing in animal models.
Drug Discovery Today, 2017A curcumin-loaded spanlastic anti-aging gel utilizing formula F5 incorporated into 2% HPMC E50 demonstrated sustained release action, compatibility, and the ability to penetrate skin layers to a depth of about 112.5 um without signs of irritation.
Saudi Pharmaceutical Journal, 2024Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.
Journal of Alternative and Complementary Medicine, 2020A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.
Journal of Cosmetic Dermatology, 2022
Ingredients
Hippophae Rhamnoides Extract, Butylene Glycol, Methyl Gluceth-20, Dipropylene Glycol, Glycerin, 1,2-Hexanediol, Niacinamide, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Melia Azadirachta Leaf Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Lemon Peel Oil, Citrus Aurantium Dulcis Peel Oil, Citrus Aurantifolia Oil, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Centella Asiatica Extract, Ascorbyl Glucoside, Ascorbic Acid, 3-O-Ethyl Ascorbic Acid, Panthenol, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycereth-26, Ammonium Acryloyldimethyltaurate Vp Copolymer, Polyglyceryl-10 Laurate, Carbomer, Allantoin, Tromethamine, Water, Hydrolyzed Jojoba Esters, Disodium Edta, Citral, Limonene
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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