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NATURIUM Azelaic Topical Acid 10% for combination skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

NATURIUM Azelaic Topical Acid 10%

High

  • SuperiorCombination Skin Fit
  • HighEffectiveness
  • ExcellentSafety

A great choice for combination skin; a few serums fit it even better.

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Excellent suitability for your combination skin and uneven skin tone is provided by potassium azeloyl diglycinate and niacinamide, which help regulate sebum and reduce acne lesions.
  • Glycerin and Tocopherol offer antioxidant support and hydration, complementing the primary actives for overall skin health.
  • The formula is safe for your skin, containing soothing ingredients and no harsh components.

How to apply

  • Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
  • Apply the serum after cleansing and toner, and right before your moisturizer.
  • Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
  • Apply the serum on clean and dry skin since your skin is not sensitive.
  • Always do a patch test before using the serum for the first time, and avoid the eye area .

People Say

★4.4Overall rating based on 600+ reviews

Most users report improved skin texture and a brighter complexion without experiencing irritation. A smaller number of users noted initial breakouts or found the scent to be unpleasant.

Highlights

  • Improves texture Mostly Mentioned
    • “face is so smooth”
    • “visibly reduced dark spots”
    • “brighter looking skin”
  • Clears acne Often Mentioned
    • “decreased congestion”
    • “nodules gone”
    • “acne improving so much”
  • Gentle and non-irritating Often Mentioned
    • “zero irritation”
    • “comfortable and hydrated”
    • “suitable for sensitive skin”
  • Reduces redness Often Mentioned
    • “calms red, pain and cysts”
    • “reduction in baseline redness”
  • Elegant texture Sometimes Noted
    • “soaks in immediately”
    • “leaves no residue”
    • “layers well”
  • Unpleasant smell Sometimes Noted
    • “smells like Elmer's glue”
    • “smells like old spit”
    • “awful smell”
  • Drying or sticky Rarely Noted
    • “little drying”
    • “leaves a very sticky feeling”
    • “not moisturizing enough”
  • Initial breakouts Rarely Noted
    • “broke me out”
    • “purging window”
    • “five/six spots at a time”
  • Slow results Rarely Noted
    • “plateaued after a few weeks”
    • “didn't completely clear skin”
    • “too soon to tell”

Sources: lovi.care, naturium.com, target.com, ulta.com, thingtesting.com, skinsort.com, and more

Questions and answers

What makes Naturium Azelaic Topical Acid 10% a great fit for combination skin?

Naturium Azelaic Topical Acid 10% is a great fit because potassium azeloyl diglycinate and niacinamide help regulate oil in oily areas and soothe uneven skin tone. Glycerin and tocopherol add gentle hydration and antioxidant support without feeling heavy on your face.

Which ingredients make this cream a good fit for combination skin?

Potassium azeloyl diglycinate and niacinamide make this a great fit for your combination skin because they help balance oily areas and soothe acne spots. Glycerin and tocopherol further support your skin with hydration and antioxidant benefits, while the formula remains gentle and safe.

What does Azelaic Acid do for combination skin?

Azelaic acid helps combination skin by calming redness, clearing breakouts, and fading dark spots while keeping the skin smooth. It is unlikely to irritate dry areas while working on oily spots. Combination skin of this type needs a balanced routine with gentle exfoliants and soothing hydrators.

Postepy Dermatologii I Alergologii, 2023Journal of Drugs in Dermatology, 2015

What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.

The British Journal of Dermatology, 2002Antioxidants, 2021

Where does this cream go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and before moisturizing, starting once a week and slowly building up if your skin tolerates it well.

Can I use this cream with retinol, and in what order?

You can use this treatment alongside a retinol by applying your retinol at night and using this azelaic acid on alternate nights or in the morning to keep your skin calm and clear. This formula contains soothing ingredients and no harsh components, making it safe for combination skin when introduced gradually.

How often should I use this cream?

This treatment is great for your combination skin when used in your evening routine, starting at once a week and slowly increasing frequency if your skin tolerates it well. The formula is safe for your skin, containing soothing ingredients and no harsh components.

Can this cream clog pores, cause breakouts or purging for combination skin?

This treatment is unlikely to clog pores or cause major breakouts for combination skin, as it contains soothing ingredients and no harsh components. Reviewers report only a low chance of initial breakouts, and ingredients like niacinamide and potassium azeloyl diglycinate help regulate sebum to keep skin clear.

Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.

    Journal of Cosmetic Dermatology, 2020

  • Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine.

    Journal of Pharmacy & Pharmaceutical Sciences, 2015

  • Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne.

    Pharmaceutics, 2021

  • Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo.

    Dermatology and Therapy, 2024

  • Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks.

    Journal of the European Academy of Dermatology and Venereology, 2023

  • Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

    Journal of Cosmetic Dermatology, 2021

  • Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

    The Journal of Investigative Dermatology, 2008

  • Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

    Dermatologic Surgery, 2005

  • Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

    Experimental Dermatology, 2003

  • Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

    Journal of Periodontology, 2009

  • Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

    Journal of Cosmetic Dermatology, 2022

  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011

  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022

  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019

Ingredients

Water, Propanediol, Potassium Azeloyl Diglycinate, Polyacrylate Crosspolymer-6, Niacinamide, Ethyl Ascorbic Acid, Caprylyl Glycol, Coffea Arabica Seed Extract Coffee Seed Extract, Sodium Hyaluronate, Phenylpropanol, Phenoxyethanol, Citric Acid, Potassium Chloride, Glycerin, Chlorphenesin, Tocopherol, Potassium Sorbate, Sodium Benzoate

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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How does it fit your skin?

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QR code: get the Lovi app
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