Natura Bissé C+C Vitamin Complex for oily acne-prone skin
Ascorbic Acid
Vitamin E
Rosa Canina Oil Fruit
Hydrolyzed CollagenLow
- AverageOily Skin Fit
- AverageEffectiveness
- ConcerningSafety
A weak match for oily acne-prone skin; the serums alongside fit it better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate skin brightening for your oily skin due to Sodium Ascorbyl Phosphate, which helps even skin tone, but it lacks sufficient ingredients for optimal oil control.
- While it provides general hydration and soothing benefits, these are largely supportive and not directly targeted at your primary concerns of acne, blemishes, and breakouts.
How to apply
- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
People Say
★4.5Overall rating based on 100+ reviewsBased on limited data, users consistently praise this serum for its potent brightening abilities, noting that it effectively revitalizes dull, tired-looking skin and improves overall radiance. The lightweight, fast-absorbing texture is a hit, though some users with sensitive skin caution against potential irritation due to the high concentration of Vitamin C and strong citrus fragrance.
Highlights
Brightens dull skin Often Mentioned
- “Instant glow”
- “revitalizes complexion”
- “looks less tired”
- “radiant finish”
High price Often Mentioned
- “Very expensive”
- “pricey investment”
- “luxury cost”
- “wallet hurting”
Lightweight texture Sometimes Noted
- “Absorbs immediately”
- “non-greasy”
- “silky feel”
- “light fluid”
Pleasant scent Sometimes Noted
- “Fresh citrus smell”
- “smells like oranges”
- “uplifting fragrance”
- “energizing scent”
Potential irritation Sometimes Noted
- “Stung slightly”
- “redness on application”
- “too strong for sensitive skin”
- “tingling sensation”
Firming effect Rarely Noted
- “Skin feels tighter”
- “improves elasticity”
- “plumper look”
- “smoother texture”
Availability issues Rarely Noted
- “Hard to find”
- “often out of stock”
- “discontinued in some stores”
- “confusing product name”
Strong fragrance Rarely Noted
- “Scent is overpowering”
- “too much perfume”
- “fragrance lingers”
- “smell is intense”
Sources: lovi.care, nordstrom.com, dermstore.com, bloomingdales.com, influenster.com, whatsinmyjar.com, and more
Questions and answers
Why is Natura Bissé C+C Vitamin Complex a weak match for oily acne-prone skin?
This treatment is a weak match because it lacks enough ingredients for oil control and does not target acne and breakouts directly. Oily acne-prone skin needs products with ingredients like niacinamide and propolis that manage excess oil and address blemishes without causing irritation.
Which ingredients make this serum a poor fit for oily acne-prone skin?
This treatment is a weak match for your skin because it lacks enough ingredients for oil control and targeting breakouts, even though it contains helpful brightening agents like Sodium Ascorbyl Phosphate. A product of this type needs effective ingredients like niacinamide and propolis that manage excess oil and smooth texture without causing irritation or breakouts.
What does Vitamin C do for oily acne-prone skin?
Vitamin C helps brighten skin, smooth out texture, and improve uneven spots for oily acne-prone skin. It may also help fade marks left behind by blemishes.
Journal of Cosmetic Dermatology, 2020Journal of Cosmetic Dermatology, 2023
What does Vitamin E do for oily acne-prone skin?
Vitamin E helps reduce oiliness, redness, and dark spots on oily acne-prone skin while improving moisture. It also helps calm irritation and smooth the skin when used consistently.
Journal of Cosmetic Dermatology, 2024Giornale Italiano Di Dermatologia E Venereologia, 2014
Where does this serum go in a skincare routine for oily acne-prone skin?
This treatment goes in the evening routine after cleansing and before moisturizing, though it is a weak match for your oily acne-prone skin. A product of this type needs dedicated oil-controlling and breakout-targeting ingredients to properly suit this skin type.
Can I use it with retinol, and in what order?
How often should I use this serum?
You can use this serum in the evening as part of your routine for oily acne-prone skin. Because it is a weak match for your skin, an oily acne-prone skin type needs a product of this type that features targeted oil-controlling and breakout-clearing ingredients.
Can it clog pores, cause breakouts or purging for oily acne-prone skin?
This treatment may not be the best match because it lacks sufficient ingredients for optimal oil control and does not target acne or blemishes. Oily acne-prone skin needs a product of this type that features targeted oil-balancing ingredients and lightweight hydrators to help keep pores clear.
Is this serum fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (parfum, limonene, and linalool).
What the research says
The tetrapeptide PKEK exerts skin whitening effects by reducing UVB-stimulated mRNA expression of pigmentation-inducing mediators like POMC and tyrosinase, and significantly fades facial pigment spots when combined with sodium ascorbyl phosphate.
Experimental Dermatology, 2012Combined ascorbyl palmitate and sodium ascorbyl phosphate treatment significantly reduced facial sebum secretions in healthy female volunteers compared to a placebo control over 90 days.
Drug Research, 2017Topical application of tocopherol succinate ethosomal gel decreased erythema, melanin, and sebum levels while improving moisture content and skin elasticity in 34 human women.
Journal of Cosmetic Dermatology, 2024Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.
Journal of Cosmetic Dermatology, 2022Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.
Journal of Cosmetic Dermatology, 2025Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.
Contemporary Clinical Trials Communications, 2021Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.
Journal of Cosmetic Dermatology, 2024Topical treatments containing rosehip extract may reduce the size and erythema of postsurgical scars through macrophage polarization and inflammatory cytokine inhibition, though current clinical evidence remains insufficient to recommend its routine use.
Journal of Cosmetic Dermatology, 2024Sunflower and rosehip oil nanoemulsions prepared with a mix of phospholipids and synthetic emulsifiers permeated intact skin to the dermis and showed a more prominent healing effect in a human organotypic skin explant culture wound model compared to nanoemulsions prepared only with phospholipids.
Pharmaceutics, 2023A nanoemulsion containing 1 mg/mL kojic dipalmitate and 5% rosehip oil demonstrated high incorporation efficiency, suitable physicochemical stability, antioxidant and depigmenting efficacy close to 1 mM ascorbic acid, and no cytotoxicity at concentrations from 0.06% to 1% in vitro.
Pharmaceutics, 2023Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris.
Journal of Cosmetic Dermatology, 2022Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks.
International Journal of Molecular Sciences, 2022Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers.
Marine Drugs, 2023
Why other serums fit oily acne-prone skin better
A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.
Clinical Pharmacology, 2018Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo.
BioMed Research International, 2022
Ingredients
Water, Sodium Ascorbyl Phosphate, Sodium Acrylates Copolymer, Propanediol, Glycerin, Hydrogenated Polyisobutene, Rosa Canina Oil Fruit, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Citric Acid, Tocopheryl Acetate, Anogeissus Leiocarpus Bark Extract, Helianthus Annuus Seed Oil Sunflower Seed Oil, Hydrolyzed Collagen, Sodium Chondroitin Sulfate, Prunus Amygdalus Dulcis Oil, Polyglyceryl-10 Stearate, Ethylhexylglycerin, Polysorbate 60, Sorbitan Stearate, Disodium Edta, Tocopherol, Potassium Sorbate, Phenoxyethanol, Parfum, Limonene, Linalool, Citrus Nobilis Oil Mandarin Orange Oil, Citrus Aurantium Dulcis Oil, Amyl Cinnamal, Yellow 5 Ci 19140
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-
Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-
Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-
Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-
Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-
Medical Board
Cosmetic chemist, SCS, IFSCC member
-
Medical Board, Medical Advisor
Dermatology MD
-
Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-
Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.